Itm2c | integral membrane protein 2C

GeneMGI:1927594Synonyms: 3110038L02Rik, Bricd2c, +2 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Limbs/digits/tail Skeleton Mortality/aging

15 No significant impact

5 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal cholesterol homeostasis1 supporting datasetItm2cem2(IMPC)TcphomozygoteEarly adult2.47x10-6 
short tibia1 supporting datasetItm2cem2(IMPC)TcphomozygoteEarly adult6.78x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetItm2ctm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Itm2cem2(IMPC)TcpIndelmouse
Itm2ctm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Itm2ctm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Itm2ctm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Itm2ctm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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