Gene: Wdr12

Name
WD repeat domain 12
MGI ID
MGI:1927241
Synonyms
Ytm1p 4933402C23Rik Ytm1
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Wdr12tm1.1(KOMP)Vlcg HOM n/a 0.00
decreased coping response Wdr12tm1.1(KOMP)Vlcg HET postnatal 7.57×10-05
embryonic lethality prior to tooth bud stage Wdr12tm1.1(KOMP)Vlcg HOM embryonic day 12.5 0.00
abnormal coat/hair pigmentation Wdr12tm1.1(KOMP)Vlcg HET postnatal 9.40×10-08

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Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Bone marrow 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (1/2) N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2) N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (1/2) N/A
Dorsal root ganglion 1  (1/47)  (1/1) N/A
Ear 2  (1/485)  (2/2) N/A
Embryo 2  (1/485)  (2/2)  Wholemount images
Eye 2  (1/485)  (2/2) N/A
Foot 2  (1/485)  (1/2) N/A
Forebrain 2  (1/485)  (1/2) N/A
Forelimb 2  (1/485)  (2/2) N/A
Fronto-nasal process 1  (1/48) Image Only N/A
Hand 2  (1/485)  (1/2) N/A
Head 2  (5/485)  (2/2) N/A
Heart 2  (1/485)  (2/2) N/A
Hindbrain 2  (6/485)  (1/2) N/A
Hindlimb 2  (1/485)  (2/2) N/A
Liver 2  (1/485)  (2/2) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485)  (2/2) N/A
Maxillary process 2  (1/485)  (2/2) N/A
Midbrain 2  (1/485)  (1/2) N/A
Nose 1  (1/51)  (1/1) N/A
Oral cavity 2  (1/485)  (1/2) N/A
Skin 2  (1/485)  (2/2) N/A
Spinal cord 1  (1/50)  (1/1) N/A
Tail 2  (1/485)  (2/2) N/A
Tail somite 2  (1/485)  (2/2) N/A

 Associated Images

Electroretinography: Cone waveform (pdf format)
4 Images
Electroretinography: Rod waveform (pdf format)
4 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Combined SHIRPA and Dysmorphology
7 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Wdr12tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Wdr12tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Wdr12tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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