Gene: Diaph3

Name
diaphanous related formin 3
MGI ID
MGI:1927222
Synonyms
Diap3 4930417P13Rik Drf3 p134MDia2 mDia2
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased mean corpuscular hemoglobin concentration Diaph3tm1b(KOMP)Mbp HET postnatal 1.32×10-06
abnormal craniofacial morphology Diaph3tm1b(KOMP)Mbp HOM embryonic day 12.5 0.00
decreased mean corpuscular volume Diaph3tm1b(KOMP)Mbp HET postnatal 7.50×10-06
embryonic growth retardation Diaph3tm1b(KOMP)Mbp HOM embryonic day 9.5 0.00
embryonic lethality prior to tooth bud stage Diaph3tm1b(KOMP)Mbp HOM embryonic day 12.5 0.00
decreased circulating triglyceride level Diaph3tm1b(KOMP)Mbp HET postnatal 2.21×10-08
decreased blood urea nitrogen level Diaph3tm1b(KOMP)Mbp HET postnatal 4.98×10-06
abnormal pericardium morphology Diaph3tm1b(KOMP)Mbp HOM embryonic day 12.5 0.00
pallor Diaph3tm1b(KOMP)Mbp HOM embryonic day 12.5 0.00
embryonic growth retardation Diaph3tm1b(KOMP)Mbp HOM embryonic day 12.5 0.00
preweaning lethality, complete penetrance Diaph3tm1b(KOMP)Mbp HOM n/a 0.00
embryonic growth retardation Diaph3tm1b(KOMP)Mbp HET embryonic day 12.5 0.00
abnormal embryo turning Diaph3tm1b(KOMP)Mbp HOM embryonic day 9.5 0.00
decreased circulating free fatty acid level Diaph3tm1b(KOMP)Mbp HET postnatal 7.28×10-10
abnormal embryo size Diaph3tm1b(KOMP)Mbp HOM embryonic day 9.5 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes
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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (1/3) N/A
Dorsal root ganglion 2  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485)  (2/3) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 2  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (1/3) N/A
Heart 2  (1/485)  (2/3) N/A
Hindbrain 2  (6/485)  (1/3) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) Image Only N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50)  (1/3) N/A
Tail 2  (1/485)  (1/3) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Gross Morphology Embryo E9.5
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Sleep Wake: Wake state (bmp file)
13 Images
X-ray: XRay Images Forepaw
10 Images
Embryo LacZ: LacZ images wholemount
12 Images
Electroretinography 2: Rod and cone PDF
6 Images
Gross Morphology Embryo E12.5
4 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Diaph3tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Diaph3tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice
Diaph3tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Diaph3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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