Genes Phenotypes

Gene: Tnip1

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Name
TNFAIP3 interacting protein 1
MGI ID
MGI:1926194
Synonyms
A20-binding inhibitor of NF-kappa B activation VAN ABIN1 Nef
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (10) Measurements chart (161) All data table (254)
Expression & images (46) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 4.59×10-08
decreased circulating iron level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.58×10-11
increased spleen weight Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 2.16×10-08
decreased circulating HDL cholesterol level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 2.15×10-20
decreased circulating fructosamine level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.19×10-20
decreased circulating glucose level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 7.20×10-06
prolonged RR interval Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 4.69×10-05
increased circulating potassium level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 4.59×10-05
decreased circulating cholesterol level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.01×10-08
decreased circulating serum albumin level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 2.36×10-11

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Oral epithelium 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (1/2) N/A
Trachea 2 No N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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MGI Allele Allele Type Produced
Tnip1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tnip1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Tnip1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Tnip1tm33632(L1L2_gt1) Targeting vectors