Gene: Tnip1

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Name
TNFAIP3 interacting protein 1
MGI ID
MGI:1926194
Synonyms
A20-binding inhibitor of NF-kappa B activation VAN ABIN1 Nef
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 4.59×10-08
decreased circulating iron level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.58×10-11
increased spleen weight Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 2.16×10-08
decreased circulating HDL cholesterol level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 2.15×10-20
decreased circulating fructosamine level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.19×10-20
decreased circulating glucose level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 7.20×10-06
prolonged RR interval Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 4.69×10-05
increased circulating potassium level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 4.59×10-05
decreased circulating cholesterol level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.01×10-08
decreased circulating serum albumin level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 2.36×10-11

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2) N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Oral epithelium 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (1/2) N/A
Trachea 2 No N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tnip1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tnip1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Tnip1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Tnip1tm33632(L1L2_gt1) Targeting vectors