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Genes Phenotypes

Gene: Tnip1

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Name
TNFAIP3 interacting protein 1
MGI ID
MGI:1926194
Synonyms
ABIN1 A20-binding inhibitor of NF-kappa B activation VAN Nef
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (24) Measurements chart (160) All data table (332)
Expression & images (67) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 9.59×10-19
decreased circulating cholesterol level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 3.70×10-12
decreased circulating HDL cholesterol level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 8.61×10-17
decreased circulating iron level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 2.53×10-12
decreased erythrocyte cell number Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 6.00×10-17
increased neutrophil cell number Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 4.50×10-08
decreased circulating glucose level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.05×10-05
decreased circulating serum albumin level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 2.71×10-12
increased mean platelet volume Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.62×10-10
increased circulating aspartate transaminase level Tnip1tm1b(EUCOMM)Hmgu HOM   Early adult 1.64×10-05
decreased lymphocyte cell number Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 2.10×10-13
increased spleen weight Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.69×10-18
increased large unstained cell number Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 7.06×10-06
increased red blood cell distribution width Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 2.49×10-19
increased monocyte cell number Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.60×10-14
increased circulating potassium level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.01×10-05
decreased hemoglobin content Tnip1tm1b(EUCOMM)Hmgu HOM   Early adult 2.06×10-05
thrombocytopenia Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 1.94×10-17
decreased heart rate Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 9.20×10-05
decreased circulating fructosamine level Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 3.73×10-21
decreased hematocrit Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 7.59×10-15
prolonged RR interval Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 4.22×10-06
increased basophil cell number Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 4.60×10-05
shortened QT interval Tnip1tm1b(EUCOMM)Hmgu HOM Early adult 3.98×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Bone 2 No N/A
Brain 2 No  (3/590)  (2/2)  Wholemount images
Brainstem 2 No  (2/590)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/590)  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590)  (2/2)  Wholemount images
Hippocampus 2 No  (3/590)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/590)  (2/2)  Wholemount images
Kidney 2 No  (20/590)  (2/2)  Wholemount images
Large intestine 2 No  (10/590)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/590)  (2/2)  Wholemount images
Lung 2 No  (1/590)  (2/2)  Wholemount images
Lymph node 2 No  (2/2)  Wholemount images
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/590)  (2/2)  Wholemount images
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/590)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/590)  (2/2)  Wholemount images
Spinal cord 2 No  (2/590)  (2/2)  Wholemount images
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590)  (2/2)  Wholemount images
Striatum 2 No  (3/590)  (2/2)  Wholemount images
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (16/590)  (1/2)  Wholemount images
Trachea 2 No  (2/590) N/A
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (2)
Heart expression
MA:0000072
digestive system (4)
Large Intestine expression
MA:0000333
endocrine system (1)
Thyroid gland expression
Parathyroid gland expression
MA:0000128
MA:0000129
immune system (3)
Lymph Node expression
MA:0000139
integumental system (1)
Skin expression
MA:0000151
nervous system (4)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Striatum expression
MA:0000191
MA:0000891
MA:0000168
MA:0000185
postnatal mouse (19)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Striatum expression
MA:0000191
MA:0000891
MA:0000168
MA:0000185
reproductive system (2)
Ovary expression
Oviduct expression
Uterus expression
MA:0000384
MA:0000389
MA:0000385
respiratory system (2)
Lung expression
MA:0000415
trunk (10)
Heart expression
MA:0000072
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/506) Image Only N/A
Ear 1  (1/506) Image Only N/A
Embryo 1  (1/507) Image Only N/A
Eye 1  (1/506) Image Only N/A
Foot 1  (1/506) Image Only N/A
Forebrain 1  (1/506) Image Only N/A
Forelimb 1  (1/506) Image Only N/A
Hand 1  (1/506) Image Only N/A
Head 1  (5/506) Image Only N/A
Heart 1  (1/506) Image Only N/A
Hindbrain 1  (6/506) Image Only N/A
Hindlimb 1  (1/506) Image Only N/A
Liver 1  (1/504) Image Only N/A
Lung 1  (1/504) Image Only N/A
Mandibular process 1  (1/506) Image Only N/A
Maxillary process 1  (1/506) Image Only N/A
Midbrain 1  (1/506) Image Only N/A
Oral cavity 1  (1/504) Image Only N/A
Skin 1  (1/506) Image Only N/A
Tail 1  (1/506) Image Only N/A
Tail somite 1  (1/506) Image Only N/A

 Associated Images

thumbnail
Adult LacZ: LacZ Images Wholemount
19 Images
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Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tnip1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Tnip1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tnip1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Tnip1tm33632(L1L2_gt1) Targeting vectors