Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
activating transcription factor 6
Synonyms:
ESTM49,  9130025P16Rik,  Atf6alpha

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Atf6 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Atf6 by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Cone Rod Dystrophy
ORPHA:1872
Achromatopsia
ORPHA:49382
Achromatopsia 7
OMIM:616517

The table below shows human diseases predicted to be associated to Atf6 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Fatty Liver Disease, Nonalcoholic, Susceptibility To, 2
Hepatic steatosis OMIM:613387
Fatty Liver Disease, Nonalcoholic, Susceptibility To, 1
Hepatic steatosis OMIM:613282
Combined Oxidative Phosphorylation Deficiency 16
Microvesicular hepatic steatosis, Elevated hepatic transaminase OMIM:615395
Hypertriglyceridemia, Transient Infantile
Elevated hepatic transaminase, Hepatic steatosis, Hepatic fibrosis, Hepatomegaly, Splenomegaly OMIM:614480
Immunodeficiency 47
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Hepatomegaly, Prolonged neonatal jau... OMIM:300972
Charcot-Marie-Tooth Disease, Axonal, Type 2Ee
Hepatic steatosis, Elevated hepatic transaminase OMIM:618400
Phosphoenolpyruvate Carboxykinase Deficiency, Mitochondrial
Hepatic steatosis, Hepatic failure OMIM:261650
Congenital Disorder Of Glycosylation, Type Iir
Micronodular cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Hepatomegaly, Jaundice,... OMIM:301045
Mitochondrial Complex Iv Deficiency, Nuclear Type 6
Hepatic steatosis OMIM:615119
Congenital Disorder Of Glycosylation, Type Iip
Hepatic steatosis, Decreased liver function, Elevated hepatic transaminase OMIM:616829
Combined Oxidative Phosphorylation Deficiency 19
Hepatic steatosis OMIM:615595
Liver Failure, Infantile, Transient
Elevated hepatic transaminase, Microvesicular hepatic steatosis, Macrovesicular hepatic steatosis... OMIM:613070
Lipodystrophy, Familial Partial, Type 5
Hepatomegaly, Hepatic steatosis OMIM:615238
Mitochondrial Dna Depletion Syndrome 15 (Hepatocerebral Type)
Cirrhosis, Elevated hepatic transaminase, Microvesicular hepatic steatosis, Cholestasis, Jaundice... OMIM:617156
Growth Retardation, Impaired Intellectual Development, Hypotonia, And Hepatopathy
Hepatic steatosis, Decreased liver function, Elevated hepatic transaminase OMIM:617093
Neutral Lipid Storage Disease With Myopathy
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase OMIM:610717
Patent Ductus Venosus
Hepatic steatosis, Decreased liver function OMIM:601466
Combined Oxidative Phosphorylation Deficiency 34
Hepatomegaly, Hepatic steatosis, Hepatic failure OMIM:617872
Mitochondrial Complex I Deficiency, Nuclear Type 11
Hepatomegaly, Macrovesicular hepatic steatosis OMIM:618234
Hemochromatosis Type 4
Hepatic steatosis, Cirrhosis, Congenital hepatic fibrosis ORPHA:139491
Familial Partial Lipodystrophy, Köbberling Type
Hepatomegaly, Hepatic steatosis, Pancreatitis ORPHA:79084
Lipodystrophy, Familial Partial, Type 4
Hepatic steatosis OMIM:613877
African Iron Overload
Peritonitis, Micronodular cirrhosis, Viral hepatitis, Hepatic steatosis, Hepatocellular carcinoma... ORPHA:139507
Peroxisomal Acyl-Coa Oxidase Deficiency
Hepatomegaly, Elevated hepatic transaminase, Diffuse hepatic steatosis OMIM:264470
Hypermethioninemia Due To Adenosine Kinase Deficiency
Elevated hepatic transaminase, Hepatic steatosis, Cholestasis, Decreased liver function, Portal f... OMIM:614300
Mitochondrial Complex Iv Deficiency, Nuclear Type 4
Hepatomegaly, Hepatic steatosis, Elevated circulating alanine aminotransferase concentration, Ele... OMIM:619048
Short Chain Acyl-Coa Dehydrogenase Deficiency
Hepatic steatosis ORPHA:26792
Morbid Obesity And Spermatogenic Failure
Hepatic steatosis OMIM:615703
Microcephalic Primordial Dwarfism-Insulin Resistance Syndrome
Hepatic steatosis ORPHA:436182
Lipodystrophy, Congenital Generalized, Type 3
Hepatomegaly, Hepatic steatosis, Hepatosplenomegaly, Splenomegaly OMIM:612526
Trappc11-Related Limb-Girdle Muscular Dystrophy R18
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase ORPHA:369840
Acquired Partial Lipodystrophy
Hepatic steatosis ORPHA:79087
Plin1-Related Familial Partial Lipodystrophy
Hepatic fibrosis, Hepatic steatosis ORPHA:280356
Combined Oxidative Phosphorylation Deficiency 21
Hepatic steatosis OMIM:615918
Lysosomal Acid Lipase Deficiency
Elevated circulating aspartate aminotransferase concentration, Cirrhosis, Increased hepatic echog... OMIM:278000
Combined Oxidative Phosphorylation Deficiency 52
Hepatic steatosis, Elevated circulating alanine aminotransferase concentration, Pancreatitis, Ele... OMIM:619386
Mitochondrial Dna Depletion Syndrome 3 (Hepatocerebral Type)
Micronodular cirrhosis, Depletion of mitochondrial DNA in liver, Hepatocellular necrosis, Elevate... OMIM:251880
Infantile Liver Failure Syndrome 3
Elevated hepatic transaminase, Hepatic steatosis, Hepatic bridging fibrosis, Acute hepatic failur... OMIM:618641
Citrullinemia, Type Ii, Adult-Onset
Hepatic steatosis, Hepatocellular carcinoma, Elevated hepatic transaminase, Pancreatitis OMIM:603471
Gracile Syndrome
Elevated hepatic iron concentration, Hepatic steatosis, Cirrhosis, Cholestasis ORPHA:53693
Mitochondrial Dna Depletion Syndrome 6 (Hepatocerebral Type)
Cirrhosis, Elevated hepatic transaminase, Microvesicular hepatic steatosis, Macrovesicular hepati... OMIM:256810
Triokinase And Fmn Cyclase Deficiency Syndrome
Hepatomegaly, Hepatic steatosis, Elevated circulating alanine aminotransferase concentration, Pan... OMIM:618805
Infantile Liver Failure Syndrome 1
Hepatomegaly, Hepatic steatosis, Acute hepatic failure, Elevated hepatic transaminase OMIM:615438
Lipodystrophy, Familial Partial, Type 6
Hepatic steatosis OMIM:615980
Hypercholesterolemia Due To Cholesterol 7Alpha-Hydroxylase Deficiency
Hepatic steatosis, Cholesterol gallstones, Macrovesicular hepatic steatosis, Cholestasis, Hepatit... ORPHA:209902
Wilson Disease
Acute hepatitis, Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Acute hepatic failu... ORPHA:905
Combined Oxidative Phosphorylation Deficiency 12
Hepatomegaly, Macrovesicular hepatic steatosis, Cholestasis OMIM:614924
Carnitine Deficiency, Systemic Primary
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase, Decreased carnitine level in liver OMIM:212140
Adrenomyodystrophy
Hepatic steatosis OMIM:300270
Severe Neurodegenerative Syndrome With Lipodystrophy
Hepatomegaly, Hepatic steatosis, Cirrhosis ORPHA:363400
Parenteral Nutrition-Associated Cholestasis
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Cholelithiasis, Biliary hyperplasia,... ORPHA:567983
Rajab Interstitial Lung Disease With Brain Calcifications 2
Hepatic steatosis, Hepatosplenomegaly, Elevated hepatic transaminase OMIM:619013
Carnitine Palmitoyltransferase I Deficiency
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase OMIM:255120
Glycogen Storage Disease Due To Phosphorylase Kinase Deficiency
Cirrhosis, Elevated hepatic transaminase, Hepatocellular adenoma, Hepatocellular carcinoma, Hepat... ORPHA:370
Ddost-Cdg
Hepatic steatosis, Elevated hepatic transaminase ORPHA:300536
Medium Chain Acyl-Coa Dehydrogenase Deficiency
Hepatomegaly, Hepatic steatosis, Decreased liver function, Elevated hepatic transaminase ORPHA:42
Chanarin-Dorfman Syndrome
Hepatomegaly, Hepatic steatosis OMIM:275630
Acyl-Coa Dehydrogenase, Medium-Chain, Deficiency Of
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase OMIM:201450
3-Hydroxyacyl-Coa Dehydrogenase Deficiency
Fulminant hepatic failure, Hepatic steatosis, Hepatic necrosis OMIM:231530
Carnitine Palmitoyltransferase Ii Deficiency, Infantile
Hepatomegaly, Macrovesicular hepatic steatosis, Elevated hepatic transaminase OMIM:600649
Porphyria Cutanea Tarda
Hepatic lobular inflammation, Elevated hepatic transaminase, Viral hepatitis, Hepatic steatosis, ... ORPHA:101330
Acyl-Coa Dehydrogenase, Very Long-Chain, Deficiency Of
Hepatomegaly, Hepatic steatosis, Periportal fibrosis, Hepatocellular necrosis OMIM:201475
Autoimmune Hepatitis
Acute hepatitis, Cirrhosis, Elevated hepatic transaminase, Viral hepatitis, Hepatocellular carcin... ORPHA:2137
Interstitial Lung And Liver Disease
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Hepatomegaly, Decreased liver function OMIM:615486
Mandibular Hypoplasia, Deafness, Progeroid Features, And Lipodystrophy Syndrome
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase OMIM:615381
Congenital Disorder Of Glycosylation, Type It
Elevated hepatic transaminase, Hepatic steatosis, Intrahepatic cholestasis, Hepatitis, Increased ... OMIM:614921
Lipodystrophy, Familial Partial, Type 3
Hepatic steatosis, Cirrhosis OMIM:604367
Crimean-Congo Hemorrhagic Fever
Jaundice, Elevated hepatic transaminase, Hepatic steatosis ORPHA:99827
Glycogen Storage Disease Due To Liver Phosphorylase Kinase Deficiency
Cirrhosis, Elevated hepatic transaminase, Hepatocellular adenoma, Hepatic steatosis, Cholestasis,... ORPHA:264580
Inclusion Body Myopathy With Paget Disease Of Bone And Frontotemporal Dementia
Hepatic steatosis ORPHA:52430
Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic
Hepatomegaly, Hepatic steatosis, Hepatic failure OMIM:261680
Chylomicron Retention Disease
Hepatic steatosis, Increased hepatocellular lipid droplets, Elevated hepatic transaminase ORPHA:71
Akt2-Related Familial Partial Lipodystrophy
Hepatomegaly, Hepatic steatosis ORPHA:79085
Cidec-Related Familial Partial Lipodystrophy
Hepatomegaly, Hepatic steatosis, Pancreatitis ORPHA:435651
Pparg-Related Familial Partial Lipodystrophy
Cirrhosis, Hepatic steatosis, Hepatomegaly, Pancreatitis, Splenomegaly ORPHA:79083
Carnitine Palmitoyl Transferase Ii Deficiency, Severe Infantile Form
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase, Hepatic failure ORPHA:228305
Mitochondrial Complex Iv Deficiency, Nuclear Type 5
Increased hepatocellular lipid droplets, Microvesicular hepatic steatosis OMIM:220111
Familial Partial Lipodystrophy, Dunnigan Type
Hepatomegaly, Hepatic steatosis, Pancreatitis, Splenomegaly ORPHA:2348
Combined Oxidative Phosphorylation Deficiency 11
Hepatomegaly, Hepatic steatosis, Decreased liver function OMIM:614922
Congenital Generalized Lipodystrophy
Hepatomegaly, Hepatic steatosis, Cirrhosis ORPHA:528
Growth Delay-Intellectual Disability-Hepatopathy Syndrome
Elevated hepatic transaminase, Hepatic steatosis, Cholestasis, Hepatic fibrosis, Hepatic failure,... ORPHA:541423
Multiple Acyl-Coa Dehydrogenase Deficiency
Hepatomegaly, Jaundice, Hepatic steatosis, Hepatic periportal necrosis OMIM:231680
Mitochondrial Neurogastrointestinal Encephalomyopathy
Cirrhosis, Macrovesicular hepatic steatosis, Elevated hepatic transaminase ORPHA:298
3-Methylglutaconic Aciduria, Type V
Microvesicular hepatic steatosis OMIM:610198
Adrenomyodystrophy
Hepatic steatosis ORPHA:977
Citrullinemia Type Ii
Elevated hepatic transaminase, Hepatic steatosis, Hepatocellular carcinoma, Hepatic fibrosis, Hep... ORPHA:247585
Primary Lipodystrophy
Hepatic steatosis, Cirrhosis, Pancreatitis, Splenomegaly ORPHA:90970
Lipe-Related Familial Partial Lipodystrophy
Hepatomegaly, Hepatic steatosis ORPHA:435660
Homocystinuria Due To Cystathionine Beta-Synthase Deficiency
Hepatic steatosis, Pancreatitis OMIM:236200
Mitochondrial Complex I Deficiency, Nuclear Type 20
Elevated hepatic transaminase, Microvesicular hepatic steatosis, Hepatic failure OMIM:611126
Carnitine-Acylcarnitine Translocase Deficiency
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase OMIM:212138
Alstrom Syndrome
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase, Chronic active hepatitis OMIM:203800
19P13.12 Microdeletion Syndrome
Hepatic steatosis ORPHA:254346
Lipodystrophy, Congenital Generalized, Type 4
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase, Splenomegaly OMIM:613327
Neutral Lipid Storage Disease With Ichthyosis
Hepatomegaly, Micronodular cirrhosis, Elevated hepatic transaminase, Hepatic steatosis ORPHA:98907
Hyperinsulinism Due To Short Chain 3-Hydroxylacyl-Coa Dehydrogenase Deficiency
Hepatic necrosis, Hepatic steatosis, Acute hepatic failure, Elevated hepatic transaminase ORPHA:71212
Acyl-Coa Dehydrogenase 9 Deficiency
Hepatic steatosis, Acute hepatic failure, Elevated hepatic transaminase ORPHA:99901
Carnitine Palmitoyltransferase Ii Deficiency, Lethal Neonatal
Elevated hepatic transaminase, Macrovesicular hepatic steatosis, Hepatomegaly, Hepatic calcificat... OMIM:608836
Fructose-1,6-Bisphosphatase Deficiency
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase ORPHA:348
Progeria-Short Stature-Pigmented Nevi Syndrome
Hepatic steatosis, Neoplasm of the pancreas, Elevated hepatic transaminase ORPHA:2959
Acquired Generalized Lipodystrophy
Hepatomegaly, Hepatic steatosis, Cirrhosis, Acute pancreatitis ORPHA:79086
Congenital Disorder Of Glycosylation, Type Ia
Hepatic fibrosis, Hepatic steatosis, Elevated hepatic transaminase, Hepatomegaly OMIM:212065
Combined Oxidative Phosphorylation Deficiency 27
Microvesicular hepatic steatosis OMIM:616672
3-Methylglutaconic Aciduria Type 7
Hepatic steatosis, Elevated hepatic transaminase ORPHA:445038
Mitochondrial Dna Depletion Syndrome 4A (Alpers Type)
Micronodular cirrhosis, Elevated hepatic transaminase, Microvesicular hepatic steatosis, Hepatome... OMIM:203700
Rajab Interstitial Lung Disease With Brain Calcifications 1
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Cholestasis, Decreased liver functio... OMIM:613658
3-Methylcrotonyl-Coa Carboxylase 1 Deficiency
Acute hepatic steatosis OMIM:210200
Mitochondrial Complex Iii Deficiency, Nuclear Type 1
Elevated hepatic transaminase, Microvesicular hepatic steatosis, Cholestasis, Cholangitis, Decrea... OMIM:124000
Autosomal Semi-Dominant Severe Lipodystrophic Laminopathy
Hepatomegaly, Hepatic steatosis, Pancreatitis, Splenomegaly ORPHA:280365
Neurologic, Endocrine, And Pancreatic Disease, Multisystem, Infantile-Onset 1
Hepatic fibrosis, Hepatic steatosis, Pancreatic fibrosis, Hepatomegaly OMIM:616263
Non-Progressive Predominantly Posterior Cavitating Leukoencephalopathy With Peripheral Neuropathy
Hepatomegaly, Decreased liver function, Diffuse hepatic steatosis ORPHA:436271
Carnitine Palmitoyl Transferase Ii Deficiency, Neonatal Form
Hepatomegaly, Hepatic steatosis, Hepatic calcification, Hepatic failure ORPHA:228308
Cimdag Syndrome
Hepatomegaly, Microvesicular hepatic steatosis, Cholelithiasis OMIM:619273
Mucopolysaccharidosis-Plus Syndrome
Hepatomegaly, Macrovesicular hepatic steatosis, Splenomegaly OMIM:617303
Dysbetalipoproteinemia
Hepatomegaly, Hepatic steatosis, Acute pancreatitis ORPHA:412
D-Bifunctional Protein Deficiency
Elevated hepatic transaminase, Hepatic steatosis, Cholestasis, Hepatomegaly, Splenomegaly, Bile d... OMIM:261515
Familial Chylomicronemia Syndrome
Hepatic steatosis, Recurrent pancreatitis, Acute pancreatitis, Jaundice, Hepatosplenomegaly ORPHA:444490
Monosomy 13Q34
Hepatic steatosis ORPHA:96168
Mitochondrial Trifunctional Protein Deficiency
Cholestasis, Chronic hepatic failure, Diffuse hepatic steatosis ORPHA:746
Abetalipoproteinemia
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Hepatic fibrosis, Hepatomegaly ORPHA:14
Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 18
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase OMIM:615356
Hnf1B-Related Autosomal Dominant Tubulointerstitial Kidney Disease
Elevated hepatic transaminase, Hepatic steatosis, Jaundice, Abnormality of exocrine pancreas phys... ORPHA:93111
Pearson Syndrome
Elevated hepatic transaminase, Exocrine pancreatic insufficiency, Hepatic steatosis, Macronodular... ORPHA:699
Arima Syndrome
Hepatic fibrosis, Hepatic steatosis, Hepatomegaly OMIM:243910
Seckel Syndrome 10
Elevated circulating aspartate aminotransferase concentration, Elevated circulating alanine amino... OMIM:617253
Lipodystrophy, Congenital Generalized, Type 1
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Acute pancreatitis, Hepatomegaly, Sp... OMIM:608594
Dilated Cardiomyopathy With Ataxia
Elevated hepatic transaminase, Microvesicular hepatic steatosis ORPHA:66634
3-Hydroxy-3-Methylglutaric Aciduria
Elevated hepatic transaminase, Acute pancreatitis, Hepatomegaly, Jaundice, Lipid accumulation in ... ORPHA:20
Lipodystrophy, Familial Partial, Type 2
Hepatomegaly, Hepatic steatosis, Acute pancreatitis OMIM:151660
Lipodystrophy, Congenital Generalized, Type 2
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Acute pancreatitis, Hepatomegaly, Sp... OMIM:269700
Mitochondrial Complex Iv Deficiency, Nuclear Type 1
Hepatomegaly, Increased hepatocellular lipid droplets, Decreased liver function OMIM:220110
Fructose Intolerance, Hereditary
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Hepatomegaly, Jaundice OMIM:229600
Neonatal Intrahepatic Cholestasis Due To Citrin Deficiency
Elevated hepatic transaminase, Hepatic steatosis, Cholestasis, Hepatomegaly, Jaundice, Hepatosple... ORPHA:247598
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency Type Ib
Hepatocellular adenoma, Hepatocellular carcinoma, Hepatic steatosis, Hepatomegaly, Pancreatitis, ... ORPHA:79259
Neutral Lipid Storage Myopathy
Elevated hepatic transaminase, Chronic pancreatitis, Hepatic steatosis, Hepatomegaly, Cholecystitis ORPHA:98908
Lysosomal Acid Lipase Deficiency
Fatal liver failure in infancy, Microvesicular hepatic steatosis, Elevated hepatic transaminase, ... ORPHA:275761
Fatal Infantile Lactic Acidosis With Methylmalonic Aciduria
Hepatomegaly, Hepatic steatosis, Elevated hepatic transaminase ORPHA:17
Alacrimia-Choreoathetosis-Liver Dysfunction Syndrome
Micronodular cirrhosis, Microvesicular hepatic steatosis, Elevated hepatic transaminase, Nodular ... ORPHA:404454
Visceral Steatosis, Congenital
Hepatic steatosis, Jaundice OMIM:228100
Turner Syndrome Due To Structural X Chromosome Anomalies
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Biliary cirrhosis, Hepatic fibrosis,... ORPHA:99413
Turner Syndrome
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Biliary cirrhosis, Hepatic fibrosis,... ORPHA:881
Mosaic Monosomy X
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Biliary cirrhosis, Hepatic fibrosis,... ORPHA:99228
Monosomy X
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Biliary cirrhosis, Hepatic fibrosis,... ORPHA:99226
Aromatase Deficiency
Hepatic steatosis ORPHA:91
1P36 Deletion Syndrome
Hepatic steatosis, Abnormality of the spleen, Abnormality of the liver, Annular pancreas ORPHA:1606
Mandibuloacral Dysplasia Progeroid Syndrome
Hepatomegaly, Macrovesicular hepatic steatosis, Elevated hepatic transaminase OMIM:619127
Atypical Werner Syndrome
Hepatic steatosis ORPHA:79474
Growth Restriction, Hypoplastic Kidneys, Alopecia, And Distinctive Facies
Hepatic steatosis OMIM:619321
Wiedemann-Rautenstrauch Syndrome
Hepatic steatosis ORPHA:3455
Homozygous Familial Hypercholesterolemia
Hepatic steatosis ORPHA:391665
Alström Syndrome
Cirrhosis, Elevated hepatic transaminase, Hepatic steatosis, Abnormal liver physiology, Hepatomeg... ORPHA:64
Cone Rod Dystrophy
ORPHA:1872
Achromatopsia
ORPHA:49382
Achromatopsia 7
OMIM:616517

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Atf6

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Atf6.

No publications found that use IMPC mice or data for Atf6.

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MGI Allele Allele Type Produced
Atf6tm44878(L1L2_Pgk_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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