Gene: Jade1 MGI:1925835

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Gene Summary

Name:
jade family PHD finger 1
Synonyms:
D530048A03Rik,  Phf17

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
male infertility Jade1tm1b(KOMP)Wtsi HOM Early adult 0.00
female infertility Jade1tm1b(KOMP)Wtsi HOM Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Jade1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Jade1 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Oocyte Maturation Defect 2
OMIM:616780
Female Infertility Due To Oocyte Meiotic Arrest
ORPHA:488191
Spermatogenic Failure 5
OMIM:243060
Oocyte Maturation Defect 9
OMIM:619011
Oocyte Maturation Defect 8
OMIM:619009
Oocyte Maturation Defect 6
OMIM:618353
Oocyte Maturation Defect 7
OMIM:618550
Preimplantation Embryonic Lethality 1
OMIM:616814
Progesterone Resistance
OMIM:264080
Spermatogenic Failure 3
OMIM:606766
Oocyte Maturation Defect 1
OMIM:615774
Oocyte Maturation Defect 3
OMIM:617712
Spermatogenic Failure 27
OMIM:617965
Spermatogenic Failure 17
OMIM:617214
Oocyte Maturation Defect 4
OMIM:617743
Oocyte Maturation Defect 5
OMIM:617996
Preimplantation Embryonic Lethality 2
OMIM:617234
Premature Ovarian Failure 19
OMIM:619245
Spermatogenic Failure 55
OMIM:619380
Spermatogenic Failure 36
OMIM:618420
Spermatogenic Failure 52
OMIM:619202
Hydatidiform Mole, Recurrent, 3
OMIM:618431
Spermatogenic Failure 31
OMIM:618112
Spermatogenic Failure 53
OMIM:619258
Spermatogenic Failure 1
OMIM:258150
Nondisjunction
OMIM:158250
Spermatogenic Failure 48
OMIM:619108
Spermatogenic Failure 43
OMIM:618751
Spermatogenic Failure 45
OMIM:619094
Spermatogenic Failure 49
OMIM:619144
Deafness-Infertility Syndrome
OMIM:611102
Spermatogenic Failure 7
OMIM:612997
Spermatogenic Failure 46
OMIM:619095
Spermatogenic Failure 44
OMIM:619044
Hydatidiform Mole, Recurrent, 4
OMIM:618432
Spermatogenic Failure 47
OMIM:619102
Spermatogenic Failure 50
OMIM:619145
Spermatogenic Failure 40
OMIM:618664
Deafness-Infertility Syndrome
ORPHA:94064
Spermatogenic Failure, X-Linked, 3
OMIM:301059
Spermatogenic Failure 11
OMIM:615081
Spermatogenic Failure 10
OMIM:614822
Spermatogenic Failure 41
OMIM:618670
Male Infertility Due To Acephalic Spermatozoa
ORPHA:529970
Oocyte Maturation Defect 10
OMIM:619176
Spermatogenic Failure 32
OMIM:618115
Spermatogenic Failure 23
OMIM:617707
Spermatogenic Failure 22
OMIM:617706
Spermatogenic Failure 42
OMIM:618745
Spermatogenic Failure 39
OMIM:618643
Spermatogenic Failure 18
OMIM:617576
Spermatogenic Failure 33
OMIM:618152
Spermatogenic Failure 34
OMIM:618153
Spermatogenic Failure 20
OMIM:617593
Spermatogenic Failure 19
OMIM:617592
Spermatogenic Failure 35
OMIM:618341
Spermatogenic Failure 54
OMIM:619379
Partial Chromosome Y Deletion
ORPHA:1646
Spermatogenic Failure 26
OMIM:617961
Spermatogenic Failure 6
OMIM:102530
Endometriosis, Susceptibility To, 1
OMIM:131200
Spermatogenic Failure, X-Linked, 2
OMIM:309120
Deafness, Autosomal Recessive 32, With Or Without Immotile Sperm
OMIM:608653
Spermatogenic Failure 16
OMIM:617187
Spermatogenic Failure 21
OMIM:617644
Isochromosomy Yp
ORPHA:98797
Spermatogenic Failure 12
OMIM:615413
Persistent Mullerian Duct Syndrome, Types I And Ii
OMIM:261550
Spermatogenic Failure 38
OMIM:618433
Asherman Syndrome
ORPHA:137686
Premature Ovarian Failure 6
OMIM:612310
Azoospermia, Obstructive, With Nephrolithiasis
OMIM:301060
Isochromosomy Yq
ORPHA:98798
Prolactin Deficiency, Isolated
OMIM:264110
Spinocerebellar Ataxia Type 32
ORPHA:276183
Fragile Site, Distamycin A Type, Rare, Fra(16)(Q22.1)
OMIM:136580
Congenital Bilateral Absence Of Vas Deferens
ORPHA:48
Heterotaxy, Visceral, 9, Autosomal, With Male Infertility
OMIM:618948
Ciliary Dyskinesia, Primary, 45
OMIM:618801
Ring Chromosome Y Syndrome
ORPHA:261529
Familial Male-Limited Precocious Puberty
ORPHA:3000
Ciliary Dyskinesia, Primary, 34
OMIM:617091
Ciliary Dyskinesia, Primary, 9
OMIM:612444
Ciliary Dyskinesia, Primary, 18
OMIM:614874
Blepharophimosis, Ptosis, And Epicanthus Inversus
OMIM:110100
Familial Isolated Hypoparathyroidism Due To Agenesis Of Parathyroid Gland
ORPHA:2239
Classic Galactosemia
ORPHA:79239
Ciliary Dyskinesia, Primary, 14
OMIM:613807
Primary Ciliary Dyskinesia
ORPHA:244
Aromatase Deficiency
ORPHA:91
Androgen Insensitivity Syndrome
ORPHA:754
Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome Plus
ORPHA:572333
47,Xyy Syndrome
ORPHA:8
Complete Androgen Insensitivity Syndrome
ORPHA:99429
Partial Androgen Insensitivity Syndrome
ORPHA:90797
Ciliary Dyskinesia, Primary, 1
OMIM:244400
Congenital Adrenal Hyperplasia Due To 17-Alpha-Hydroxylase Deficiency
ORPHA:90793
Fanconi Anemia, Complementation Group A
OMIM:227650
Turner Syndrome Due To Structural X Chromosome Anomalies
ORPHA:99413
Turner Syndrome
ORPHA:881
Mosaic Monosomy X
ORPHA:99228
Monosomy X
ORPHA:99226
46,Xy Partial Gonadal Dysgenesis
ORPHA:251510
Bloom Syndrome
ORPHA:125
45,X/46,Xy Mixed Gonadal Dysgenesis
ORPHA:1772
Cystinosis, Nephropathic
OMIM:219800
Cystic Fibrosis
OMIM:219700
Noonan Syndrome 1
OMIM:163950

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Jade1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Jade1.

No publications found that use IMPC mice or data for Jade1.

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MGI Allele Allele Type Produced
Jade1tm119139(L1L2_Pgk_P) Targeting vectors
Jade1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Jade1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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