Ddx52 | DExD box helicase 52

GeneMGI:1925644Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 52, 2700029C06Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetDdx52tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased startle reflex1 supporting datasetDdx52tm1a(EUCOMM)WtsiheterozygoteEarly adult1.44x10-5 
increased circulating phosphate level1 supporting datasetDdx52tm1a(EUCOMM)WtsiheterozygoteEarly adult3.24x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ddx52tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ddx52tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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