Gene: Orai1

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Name
ORAI calcium release-activated calcium modulator 1
MGI ID
MGI:1925542
Synonyms
D730049H07Rik Tmem142a
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Orai1tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
unresponsive to tactile stimuli Orai1tm1b(EUCOMM)Hmgu HOM E18.5 0.00
unresponsive to tactile stimuli Orai1tm1b(EUCOMM)Hmgu HET E18.5 0.00
abnormal embryo size Orai1tm1b(EUCOMM)Hmgu HOM E18.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Wholemount images
Aorta 2 No  (1/583)  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583)  (2/2)  Wholemount images
Cecum 1 No  (12/371) N/A
Cerebellum 2 No  (3/583)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/583)  Wholemount images
Hippocampus 2 No  (3/583)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2) N/A
Large intestine 2 No  (10/583)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/583)  (2/2)  Wholemount images
Lung 2 No  (2/583)  (2/2) N/A
Lymph node 2 No  (1/583)  (2/2) N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No  (2/2)  Wholemount images
Olfactory lobe 2 No  (2/583)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/583)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/583)  (2/2)  Wholemount images
Parathyroid gland 2 No  (1/563)  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (1/2)  Wholemount images
Prostate gland 2 No  (12/583)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (2/2)  Wholemount images
Small intestine 2 No  (9/583)  (2/2)  Wholemount images
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583)  (2/2)  Wholemount images
Striatum 2 No  (3/583)  (2/2)  Wholemount images
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583)  (2/2)  Wholemount images
Trachea 2 No  (3/583)  (2/2)  Wholemount images
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2)  Wholemount images
Vas deferens 2 No  (15/382)  (1/2)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
1  (1/60)  (1/1) N/A
1  (1/64)  (1/1) N/A
1  (6/505)  (1/1) N/A
1  (1/73)  (1/1) N/A
1  (1/64)  (1/1) N/A
1  (1/60)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/506)  (1/1) N/A
1  (1/71)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/55)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/302)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/61)  (1/1) N/A
1  (1/59)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (5/505)  (1/1) N/A
1  (1/60)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/60)  (1/1) N/A
1  (6/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/64)  (1/1) N/A
1  (1/64)  (1/1) N/A
1  (1/58)  (1/1) N/A
1  (1/503)  (1/1) N/A
1  (1/302)  (1/1) N/A
1  (1/503)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/55)  (1/1) N/A
1  (1/55) N/A
1  (1/55)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/60)  (1/1) N/A
1  (1/75)  (1/1) N/A
1  (1/60)  (1/1) N/A
1  (1/503)  (1/1) N/A
1  (1/60)  (1/1) N/A
1  (1/55)  (1/1) N/A
1  (1/55)  (1/1) N/A
1  (1/56)  (1/1) N/A
1  (1/64)  (1/1) N/A
1  (1/57)  (1/1) N/A
1  (1/75)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/72)  (1/1) N/A
1  (1/55)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/55)  (1/1) N/A
1  (1/55)  (1/1) N/A
1  (1/59)  (1/1) N/A
1  (1/60)  (1/1) N/A
1  (1/60)  (1/1) N/A
1  (1/60)  (1/1) N/A
1  (1/302)  (1/1) N/A
1  (1/302)  (1/1) N/A
1  (1/59)  (1/1) N/A
1  (1/71)  (1/1) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Adult LacZ: LacZ Images Wholemount
19 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Forepaw
10 Images
Immunophenotyping: Panel A FCS file(s)
6 Images
Immunophenotyping: Panel B FCS file(s)
6 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Orai1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Orai1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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