Gene: Map4k5

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Name
mitogen-activated protein kinase kinase kinase kinase 5
MGI ID
MGI:1925503
Synonyms
KHS MAPKKKK5 GCKR 4432415E19Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased total body fat amount Map4k5tm1b(EUCOMM)Hmgu HOM Early adult 2.64×10-05
abnormal kidney morphology Map4k5tm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal bone structure Map4k5tm1b(EUCOMM)Hmgu HOM Early adult 3.47×10-05
decreased body length Map4k5tm1b(EUCOMM)Hmgu HOM Early adult 3.16×10-11

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Map4k5tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Map4k5tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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