Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
dual serine/threonine and tyrosine protein kinase
Synonyms:
A930019K20Rik,  C430014H23Rik

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Dstyk mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Dstyk by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Congenital Anomalies Of Kidney And Urinary Tract 1
OMIM:610805
Autosomal Recessive Spastic Paraplegia Type 23
ORPHA:101003
Spastic Paraplegia 23, Autosomal Recessive
OMIM:270750

The table below shows human diseases predicted to be associated to Dstyk by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Monoamine Oxidase A Deficiency
Cognitive impairment ORPHA:3057
Congenital Anomalies Of Kidney And Urinary Tract 1
OMIM:610805
Autosomal Recessive Spastic Paraplegia Type 23
ORPHA:101003
Spastic Paraplegia 23, Autosomal Recessive
OMIM:270750

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Dstyk

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Dstyk.

No publications found that use IMPC mice or data for Dstyk.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Dstyktm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Dstyktm1e(EUCOMM)Wtsi Targeted, non-conditional allele ES Cells

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