Genes Phenotypes

Gene: Smpd4

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Name
sphingomyelin phosphodiesterase 4
MGI ID
MGI:1924876
Synonyms
neutral membrane (neutral sphingomyelinase-3) 4122402O22Rik
Viability
Homozygous - Subviable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (2) Measurements chart (405) All data table (1012)
Expression & images (45) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, incomplete penetrance Smpd4tm2b(KOMP)Wtsi HOM Early adult 0.00
male infertility Smpd4tm2b(KOMP)Wtsi HOM Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/2) N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (1/2) N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Smpd4tm2b(KOMP)Wtsi
hypothalamus, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
trigeminal V nerve, peripheral nervous system, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
trachea, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
cartilage tissue, rib, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
heart, HET, Female, WTSI

View all 13 images

Smpd4tm2b(KOMP)Wtsi
trachea, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
cartilage tissue, rib, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
heart, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
oviduct, uterus, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
adrenal gland, HET, Female, WTSI

View all 11 images

Smpd4tm2b(KOMP)Wtsi
hypothalamus, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
trigeminal V nerve, peripheral nervous system, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
spinal cord, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
oviduct, uterus, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
testis, HET, Male, WTSI
Smpd4tm2b(KOMP)Wtsi
prostate gland, HET, Male, WTSI
Smpd4tm2b(KOMP)Wtsi
kidney, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
lower urinary tract, urinary bladder, HET, Male, WTSI
Smpd4tm2b(KOMP)Wtsi
heart, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
adrenal gland, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
prostate gland, HET, Male, WTSI
Smpd4tm2b(KOMP)Wtsi
thymus, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
cartilage tissue, rib, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
trachea, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
cartilage tissue, rib, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
28 Images
X-ray: XRay Images Whole Body Dorso Ventral
42 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Forepaw
14 Images
DSS Histology
8 Images
Eye Morphology: Images Slit Lamp
2 Images
Anti-nuclear antibody assay
6 Images
Legacy Phenotype Associated Images
Smpd4tm2b(KOMP)Wtsi
HET, Male, WTSI
Smpd4tm2b(KOMP)Wtsi
HET, Male, WTSI
Smpd4tm2b(KOMP)Wtsi
HET, Male, WTSI
Smpd4tm2b(KOMP)Wtsi
HET, Male, WTSI
Smpd4tm2b(KOMP)Wtsi
HET, Male, WTSI

View all 70 images

Smpd4tm2b(KOMP)Wtsi
TS20 liver, HET, Male, WTSI
Smpd4tm2b(KOMP)Wtsi
TS20 maxillary process, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
TS20 forelimb, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
TS20 stomach, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
TS20 chorioallantoic placenta, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
HOM, Unsexed, WTSI
Smpd4tm2b(KOMP)Wtsi
HOM, Unsexed, WTSI
Smpd4tm2b(KOMP)Wtsi
narrow eye opening, HET, Female, WTSI
Smpd4tm2b(KOMP)Wtsi
abnormal cornea morphology, HET, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Smpd4tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Smpd4tm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Smpd4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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