Mthfd1l | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

GeneMGI:1924836Synonyms: Fthfsdc1, 2410004L15Rik

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

19 No significant impact

4 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:1Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetMthfd1ltm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mthfd1ltm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Mthfd1ltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Mthfd1ltm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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Mthfd1ltm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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