Sec24a | SEC24 homolog A, COPII coat complex component
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Skeleton
16 No significant impact
5 Not tested
Data collections
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
decreased body weight | 3 supporting datasets | Sec24atm1a(KOMP)Wtsi | homozygote | Early adult | 8.17x10-7 | ||
increased circulating alanine transaminase level | 1 supporting dataset | Sec24atm1a(KOMP)Wtsi | homozygote | Early adult | 1.21x10-12 | ||
decreased circulating cholesterol level | 1 supporting dataset | Sec24atm1a(KOMP)Wtsi | homozygote | Early adult | 3.62x10-10 | ||
decreased circulating HDL cholesterol level | 1 supporting dataset | Sec24atm1a(KOMP)Wtsi | homozygote | Early adult | 1.08x10-9 | ||
increased bone mineral density | 1 supporting dataset | Sec24atm1a(KOMP)Wtsi | homozygote | Early adult | 3.34x10-5 | ||
increased lactate dehydrogenase level | 1 supporting dataset | Sec24atm1a(KOMP)Wtsi | homozygote | Early adult | 2.08x10-5 | ||
increased blood urea nitrogen level | 1 supporting dataset | Sec24atm1a(KOMP)Wtsi | homozygote | Early adult | 1.84x10-5 | ||
decreased circulating LDL cholesterol level | 1 supporting dataset | Sec24atm1a(KOMP)Wtsi | homozygote | Early adult | 3.23x10-5 |
| | | | | | | | | |
External links
No external links available for Sec24a.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Sec24atm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Sec24atm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |