Genes Phenotypes

Gene: Sorbs2

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Name
sorbin and SH3 domain containing 2
MGI ID
MGI:1924574
Synonyms
2010203O03Rik 9430041O17Rik
Viability
Homozygous - Viable
Embryo Screen
N/A
Other links
MGI   Ensembl  
Significant phenotypes (11) Measurements chart (245) All data table (365)
Expression & images (73) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
shortened PQ interval Sorbs2tm1.1(KOMP)Mbp HOM postnatal 4.18×10-08
shortened PR interval Sorbs2tm1.1(KOMP)Mbp HOM postnatal 4.11×10-07
decreased circulating HDL cholesterol level Sorbs2tm1.1(KOMP)Mbp HOM postnatal 1.95×10-05
decreased circulating glucose level Sorbs2tm1.1(KOMP)Mbp HOM postnatal 3.61×10-06
shortened ST segment Sorbs2tm1.1(KOMP)Mbp HOM postnatal 4.97×10-05
decreased circulating free fatty acid level Sorbs2tm1.1(KOMP)Mbp HOM postnatal 5.46×10-05
decreased vertical activity Sorbs2tm1.1(KOMP)Mbp HOM postnatal 2.53×10-06
abnormal retina morphology Sorbs2tm1.1(KOMP)Mbp HOM postnatal 1.51×10-05
decreased circulating cholesterol level Sorbs2tm1.1(KOMP)Mbp HOM postnatal 5.45×10-05
increased heart rate Sorbs2tm1.1(KOMP)Mbp HOM postnatal 3.42×10-05
hypoactivity Sorbs2tm1.1(KOMP)Mbp HOM postnatal 1.70×10-07

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No  (2/2) N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/3) N/A
Dorsal root ganglion 2  (1/47) Image Only N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485)  (2/3) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 2  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485)  (2/3) N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485)  (2/3) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) Image Only N/A
Spinal cord 2  (1/50)  (2/3) N/A
Tail 2  (1/485)  (2/3) N/A
Tail somite 2  (1/485) N/A
embryo or Unassigned (12)
Embryo imageOnly
EMAPA:16039 embryo

 Associated Images

Sleep Wake: Wake state (bmp file)
10 Images
X-ray: XRay Images Dorso Ventral
9 Images
X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Lateral Orientation
9 Images
Embryo LacZ: LacZ images wholemount
12 Images
Combined SHIRPA and Dysmorphology
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Sorbs2tm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Sorbs2tm1.1(KOMP)Mbp Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Sorbs2tm443565(L1L2_Bact_P) Targeting vectors

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