Gene: Sorbs2

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Name
sorbin and SH3 domain containing 2
MGI ID
MGI:1924574
Synonyms
9430041O17Rik 2010203O03Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal retina morphology Sorbs2tm1.1(KOMP)Mbp HOM Early adult 1.81×10-06
decreased circulating glucose level Sorbs2tm1.1(KOMP)Mbp HOM Early adult 2.59×10-06
increased heart rate Sorbs2tm1.1(KOMP)Mbp HOM   Early adult 2.63×10-05
decreased exploration in new environment Sorbs2tm1.1(KOMP)Mbp HOM Early adult 2.09×10-06
shortened PQ interval Sorbs2tm1.1(KOMP)Mbp HOM   Early adult 3.98×10-06
shortened PR interval Sorbs2tm1.1(KOMP)Mbp HOM   Early adult 1.18×10-05
shortened ST segment Sorbs2tm1.1(KOMP)Mbp HOM Early adult 7.11×10-05
increased mean corpuscular hemoglobin Sorbs2tm1.1(KOMP)Mbp HOM   Early adult 4.23×10-05
shortened RR interval Sorbs2tm1.1(KOMP)Mbp HOM   Early adult 2.14×10-06
increased circulating sodium level Sorbs2tm1.1(KOMP)Mbp HOM Early adult 3.88×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (4/583) N/A
Aorta 1 No  (1/583)  (1/1)  Section images
Brain 1 No  (4/583) N/A
Brainstem 1 No  (2/583) N/A
Brown adipose tissue 1 No N/A
Cartilage tissue 1 No  (1/583) N/A
Cerebellum 1 No  (3/583) N/A
Cerebral cortex 1 No  (2/583) N/A
Epididymis 1 No  (18/132) N/A
Esophagus 1 No  (7/407) N/A
Eye 1 No N/A
Heart 1 No  (2/583)  (1/1)  Section images
Hippocampus 1 No  (3/583) N/A
Hypothalamus 1 No  (2/583) N/A
Kidney 1 No  (21/583)  (1/1)  Section images
Large intestine 1 No  (10/583) N/A
Liver 1 No N/A
Lower urinary tract 1 No  (1/583) N/A
Lung 1 No  (2/583) N/A
Lymph node 1 No  (1/583) N/A
Mammary gland 1 No N/A
Midbrain 1 No N/A
Olfactory lobe 1 No  (2/583) N/A
Ovary 1 No  (1/583) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/583) N/A
Peripheral nervous system 1 No  (2/583) N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No  (1/583) N/A
Prostate gland 1 No  (12/583) N/A
Skeletal muscle 1 No N/A
Skin 1 No  (1/583) N/A
Small intestine 1 No  (9/583) N/A
Spinal cord 1 No  (3/583)  (1/1) N/A
Spleen 1 No  (3/583) N/A
Stomach 1 No  (13/583)  (1/1)  Section images
Striatum 1 No  (3/583) N/A
Submandibular gland 1 No  (2/130)  (1/1)  Section images
Testis 1 No  (6/583)  (1/1)  Section images
Thalamus 1 No N/A
Thymus 1 No  (1/583) N/A
Thyroid gland 1 No  (17/583) N/A
Trachea 1 No  (3/583) N/A
Urinary bladder 1 No N/A
Uterus 1 No N/A
Vascular system 1 No  (1/1)  Section images
Vesicular gland 1 No N/A
White adipose tissue 1 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (2/3) N/A
2  (1/60) Image Only N/A
2  (1/505) N/A
2  (1/506)  (2/3)  Wholemount images
2  (1/505) N/A
2  (1/505) N/A
2  (1/505)  (2/3) N/A
2  (1/505) N/A
2  (1/61) N/A
2  (1/505) N/A
2  (5/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (6/505)  (2/3) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/503) Image Only N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505)  (2/3) N/A
2  (1/75) N/A
2  (1/503) N/A
2  (1/505) Image Only N/A
2  (1/72)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505) N/A

 Associated Images

Eye Morphology: Images Ophthalmoscopy
28 Images
Original Image
Adult LacZ: LacZ Images Section
7 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
Sleep Wake: Wake state (bmp file)
10 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Combined SHIRPA and Dysmorphology
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Sorbs2tm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Sorbs2tm1.1(KOMP)Mbp Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Sorbs2tm443565(L1L2_Bact_P) Targeting vectors

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