Gene: Ankrd11

Name
ankyrin repeat domain 11
MGI ID
MGI:1924337
Synonyms
Yod 2410104C19Rik 3010027A04Rik 9530048I21Rik
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating HDL cholesterol level Ankrd11tm1b(EUCOMM)Wtsi HET postnatal 1.80×10-05
abnormal bone mineralization Ankrd11Yod HET postnatal 5.76×10-10
increased circulating cholesterol level Ankrd11tm1b(EUCOMM)Wtsi HET postnatal 7.60×10-05
decreased bone mineral density Ankrd11Yod HET postnatal 5.99×10-14
increased or absent threshold for auditory brainstem response Ankrd11tm1b(EUCOMM)Wtsi HET postnatal 0.00
decreased startle reflex Ankrd11tm1b(EUCOMM)Wtsi HET postnatal 1.34×10-09
increased lean body mass Ankrd11Yod HET postnatal 2.05×10-07
abnormal bone structure Ankrd11Yod HET postnatal 2.60×10-06
absent startle reflex Ankrd11tm1b(EUCOMM)Wtsi HET postnatal 2.47×10-16
abnormal vitreous body morphology Ankrd11tm1b(EUCOMM)Wtsi HET postnatal 2.18×10-05
abnormal response to new environment Ankrd11Yod HET postnatal 6.52×10-05
decreased body length Ankrd11tm1b(EUCOMM)Wtsi HET postnatal 1.10×10-06
decreased body weight Ankrd11Yod HET postnatal 2.55×10-12
decreased bone mineral density Ankrd11tm1b(EUCOMM)Wtsi HET postnatal 1.24×10-05
preweaning lethality, complete penetrance Ankrd11tm1b(EUCOMM)Wtsi HOM n/a 0.00
mammalian phenotype Ankrd11Yod HET postnatal 1.95×10-07
increased total body fat amount Ankrd11Yod HET postnatal 3.15×10-07
abnormal embryo development Ankrd11tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
decreased circulating amylase level Ankrd11Yod HET postnatal 3.34×10-06
abnormal retinal vasculature morphology Ankrd11Yod HET postnatal 1.43×10-05

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Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Ear 2  (1/485)  (2/2) N/A
Embryo 2  (1/485)  (2/2) N/A
Eye 2  (1/485)  (2/2) N/A
Foot 2  (1/485)  (2/2) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485)  (2/2) N/A
Hand 2  (1/485)  (2/2) N/A
Head 2  (5/485)  (2/2) N/A
Heart 2  (1/485)  (2/2) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485)  (2/2) N/A
Liver 2  (1/485)  (2/2) N/A
Lung 2  (1/485)  (2/2) N/A
Mandibular process 2  (1/485)  (2/2) N/A
Maxillary process 2  (1/485)  (2/2) N/A
Midbrain 2  (1/485) N/A
Oral cavity 2  (1/485)  (2/2) N/A
Skin 2  (1/485)  (2/2) N/A
Tail 2  (1/485)  (1/2) N/A
Tail somite 2  (1/485)  (1/2) N/A

 Associated Images

Gross Morphology Embryo E9.5
3 Images
X-ray: XRay Images Dorso Ventral
10 Images
Embryo LacZ: LacZ images wholemount
2 Images
X-ray: XRay Images Lateral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Ankrd11tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ankrd11tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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