Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Lrrc52 by phenotypic similarity.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Lrrc52.
There are 2 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
LRRC52 regulates BK channel function and localization in mouse cochlear inner hair cells. | Proceedings of the National Academy of Sciences of the United States of America (August 2019) | Lrrc52tm1.1(KOMP)Vlcg | 31451634 |
SLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertility. | Proceedings of the National Academy of Sciences of the United States of America (February 2015) | Lrrc52tm1(KOMP)Vlcg Lrrc52tm1.1(KOMP)Vlcg | PMC4345599 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Lrrc52tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | ES Cells |
Lrrc52tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Lrrc52tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | ES Cells |
Lrrc52tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | ES Cells |
Lrrc52tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
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