Trappc9 | trafficking protein particle complex 9

GeneMGI:1923760Synonyms: 2900005P22Rik, TRS130, +3 more

Physiological systems

18 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Integument Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

10 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:19Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased fasting circulating glucose level1 supporting datasetTrappc9tm1a(EUCOMM)WtsihomozygoteEarly adult3.02x10-12 
decreased CD11b-low dendritic cell number1 supporting datasetTrappc9tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased circulating sodium level1 supporting datasetTrappc9tm1a(EUCOMM)WtsihomozygoteEarly adult2.5x10-5 
increased circulating insulin level1 supporting datasetTrappc9tm1a(EUCOMM)WtsihomozygoteEarly adult9.94x10-16 
decreased lean body mass1 supporting datasetTrappc9tm1a(EUCOMM)WtsihomozygoteEarly adult2.12x10-21 
increased Ly6C high monocyte number1 supporting datasetTrappc9tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased red blood cell distribution width1 supporting datasetTrappc9tm1a(EUCOMM)WtsihomozygoteEarly adult4.85x10-6 
decreased grip strength3 supporting datasetsTrappc9tm1a(EUCOMM)WtsihomozygoteEarly adult8.19x10-7 
impaired glucose tolerance1 supporting datasetTrappc9tm1a(EUCOMM)WtsihomozygoteEarly adult2.11x10-9 
decreased KLRG1-positive NK cell number1 supporting datasetTrappc9tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trappc9tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Trappc9tm1c(EUCOMM)WtsiWild type floxed exon (post-Flp)mouse
Trappc9tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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