Genes Phenotypes

Gene: Daam2

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Name
dishevelled associated activator of morphogenesis 2
MGI ID
MGI:1923691
Synonyms
2310016D11Rik
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (12) Measurements chart (392) All data table (862)
Expression & images (67) Disease models (0) Histopathology (1) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal bone structure Daam2tm1a(KOMP)Wtsi HOM Early adult 3.11×10-05
increased circulating phosphate level Daam2tm1b(KOMP)Wtsi HOM Early adult 3.20×10-05
abnormal cranium morphology Daam2tm1a(KOMP)Wtsi HOM Early adult 5.22×10-09
abnormal snout morphology Daam2tm1b(KOMP)Wtsi HOM Early adult 3.21×10-10
long snout Daam2tm1a(KOMP)Wtsi HOM Early adult 2.27×10-09
decreased body length Daam2tm1a(KOMP)Wtsi HOM Early adult 1.47×10-13
increased circulating alkaline phosphatase level Daam2tm1a(KOMP)Wtsi HOM Early adult 8.03×10-07
abnormal maxilla morphology Daam2tm1a(KOMP)Wtsi HOM Early adult 2.34×10-05
decreased lean body mass Daam2tm1a(KOMP)Wtsi HOM Early adult 8.22×10-05
abnormal maxilla morphology Daam2tm1b(KOMP)Wtsi HOM Early adult 1.63×10-08
abnormal snout morphology Daam2tm1a(KOMP)Wtsi HOM Early adult 4.65×10-10
decreased circulating insulin level Daam2tm1a(KOMP)Wtsi HOM Early adult 8.21×10-06

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (1/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (2)
Heart expression
MA:0000072
digestive system (3)
Gall Bladder expression
MA:0000356
endocrine system (2)
Adrenal gland expression
MA:0000116
integumental system (1)
Skin expression
MA:0000151
musculoskeletal system (2)
Cartilage tissue expression
Bone expression
MA:0000104
MA:0001459
nervous system (5)
Cartilage tissue expression
Bone expression
Spinal cord expression
MA:0000104
MA:0001459
MA:0000216
postnatal mouse (18)
Adrenal gland expression
MA:0000116
reproductive system (2)
Ovary expression
Oviduct expression
Uterus expression
MA:0000384
MA:0000385
MA:0000389
respiratory system (2)
Lung expression
MA:0000415
set of connective tissues (2)
Cartilage tissue expression
Bone expression
MA:0000104
MA:0001459
trunk (11)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (2/4) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505)  (4/4) N/A
Eye 2  (1/504)  (3/4) N/A
Foot 2  (1/504)  (2/4) N/A
Forebrain 2  (1/504)  (1/4) N/A
Forelimb 2  (1/504)  (4/4) N/A
Hand 2  (1/503)  (2/4) N/A
Head 2  (5/504)  (4/4) N/A
Heart 2  (1/504)  (2/4) N/A
Hindbrain 2  (6/504)  (2/4) N/A
Hindlimb 2  (1/503)  (4/4) N/A
Liver 2  (1/504)  (2/4) N/A
Lung 2  (1/500)  (2/4) N/A
Mandibular process 2  (1/504)  (2/4) N/A
Maxillary process 2  (1/504)  (2/4) N/A
Midbrain 2  (1/504)  (1/4) N/A
Oral cavity 2  (1/504)  (1/4) N/A
Skin 2  (1/504)  (1/4) N/A
Tail 2  (1/504)  (4/4) N/A
Tail somite 2  (1/504)  (2/4) N/A

 Associated Images

Brain Histopathology: Hippocampal section
3 Images
Brain Histopathology: Cerebellar Section
3 Images
Brain Histopathology: Striatal Section
3 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
53 Images
X-ray: XRay Images Whole Body Lateral Orientation
39 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
25 Images
Adult LacZ: LacZ Images Wholemount
18 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
Legacy Phenotype Associated Images
Daam2tm1a(KOMP)Wtsi
HOM, Male, WTSI
Daam2tm1a(KOMP)Wtsi
HOM, Male, WTSI
Daam2tm1a(KOMP)Wtsi
HOM, Male, WTSI
Daam2tm1a(KOMP)Wtsi
HOM, Male, WTSI
Daam2tm1a(KOMP)Wtsi
HOM, Female, WTSI

View all 70 images

Daam2tm1a(KOMP)Wtsi
HOM, Male, WTSI
Daam2tm1a(KOMP)Wtsi
primary motor cortex, decreased primary motor cortex size, HOM, Male, WTSI
Daam2tm1a(KOMP)Wtsi
HOM, Male, WTSI
Daam2tm1a(KOMP)Wtsi
HOM, Male, WTSI
Daam2tm1a(KOMP)Wtsi
primary motor cortex, decreased primary motor cortex size, HOM, Male, WTSI

View all 9 images

Daam2tm1a(KOMP)Wtsi
abnormal retinal pigmentation, HOM, Female, WTSI
Daam2tm1a(KOMP)Wtsi
abnormal cornea morphology, HOM, Female, WTSI
Daam2tm1a(KOMP)Wtsi
abnormal retinal blood vessel morphology, HOM, Male, WTSI
Daam2tm1a(KOMP)Wtsi
abnormal cornea morphology, HOM, Female, WTSI
Daam2tm1a(KOMP)Wtsi
back skin, HOM, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Brain - developmental and structural abnormality Daam2tm1a(KOMP)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Daam2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Daam2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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