Genes Phenotypes

Gene: Daam2

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Name
dishevelled associated activator of morphogenesis 2
MGI ID
MGI:1923691
Synonyms
2310016D11Rik
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (10) Measurements chart (390) All data table (506)
Expression & images (67) Disease models (0) Histopathology (1) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased body length Daam2tm1a(KOMP)Wtsi HOM postnatal 8.20×10-11
abnormal snout morphology Daam2tm1a(KOMP)Wtsi HOM postnatal 7.06×10-10
abnormal maxilla morphology Daam2tm1a(KOMP)Wtsi HOM postnatal 2.42×10-05
abnormal bone structure Daam2tm1a(KOMP)Wtsi HOM postnatal 3.32×10-05
abnormal snout morphology Daam2tm1b(KOMP)Wtsi HOM postnatal 5.02×10-10
abnormal maxilla morphology Daam2tm1b(KOMP)Wtsi HOM postnatal 2.24×10-08
increased circulating phosphate level Daam2tm1b(KOMP)Wtsi HOM postnatal 2.14×10-05
increased circulating alkaline phosphatase level Daam2tm1a(KOMP)Wtsi HOM postnatal 8.35×10-07
decreased circulating insulin level Daam2tm1a(KOMP)Wtsi HOM postnatal 1.83×10-05
abnormal cranium morphology Daam2tm1a(KOMP)Wtsi HOM postnatal 4.89×10-09

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (1/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (2)
Heart expression
MA:0000072
digestive system (3)
Gall Bladder expression
MA:0000356
endocrine system (2)
Adrenal gland expression
MA:0000116
integumental system (1)
Skin expression
MA:0000151
musculoskeletal system (2)
Cartilage tissue expression
Bone expression
MA:0000104
MA:0001459
nervous system (5)
Cartilage tissue expression
Bone expression
Spinal cord expression
MA:0000104
MA:0001459
MA:0000216
postnatal mouse (18)
Adrenal gland expression
MA:0000116
reproductive system (2)
Ovary expression
Oviduct expression
Uterus expression
MA:0000384
MA:0000385
MA:0000389
respiratory system (2)
Lung expression
MA:0000415
set of connective tissues (2)
Cartilage tissue expression
Bone expression
MA:0000104
MA:0001459
trunk (11)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/4) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485)  (3/4) N/A
Foot 2  (1/485)  (4/4) N/A
Forebrain 2  (1/485)  (1/4) N/A
Forelimb 2  (1/485)  (4/4) N/A
Hand 2  (1/485)  (4/4) N/A
Head 2  (5/485)  (3/4) N/A
Heart 2  (1/485)  (2/4) N/A
Hindbrain 2  (6/485)  (2/4) N/A
Hindlimb 2  (1/485)  (4/4) N/A
Liver 2  (1/485)  (2/4) N/A
Lung 2  (1/485)  (2/4) N/A
Mandibular process 2  (1/485)  (2/4) N/A
Maxillary process 2  (1/485)  (2/4) N/A
Midbrain 2  (1/485)  (1/4) N/A
Oral cavity 2  (1/485)  (1/4) N/A
Skin 2  (1/485)  (1/4) N/A
Tail 2  (1/485)  (4/4) N/A
Tail somite 2  (1/485)  (2/4) N/A

 Associated Images

Brain Histopathology: Hippocampal section
3 Images
Brain Histopathology: Cerebellar Section
3 Images
Brain Histopathology: Striatal Section
3 Images
X-ray: XRay Images Dorso Ventral
53 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
25 Images
Adult LacZ: LacZ Images Wholemount
18 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Lateral Orientation
39 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Brain - developmental and structural abnormality Daam2tm1a(KOMP)Wtsi HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Daam2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Daam2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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