Churc1 | churchill domain containing 1
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system
15 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:78Adult tissues
27Embryo tissues
enlarged thymus | 1 supporting dataset | Churc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
abnormal thymus morphology | 1 supporting dataset | Churc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
enlarged heart | 1 supporting dataset | Churc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
abnormal spleen morphology | 1 supporting dataset | Churc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
abnormal heart morphology | 1 supporting dataset | Churc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
increased effector memory T-helper cell number | 1 supporting dataset | Churc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.07x10-7 | ||
abnormal eye morphology | 1 supporting dataset | Churc1tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
| | | | | | | | | |
adrenal gland | heterozygote | Section images | 0% (0/2) | 0.7% (4/570) |
aorta | heterozygote | Section images | 100% (2/2) | 0.19% (1/533) |
blood | heterozygote | n/a | n/a | 0% (0/17) |
bone | heterozygote | Section images | 50% (1/2) | 0% (0/394) |
bone marrow | heterozygote | n/a | n/a | 0% (0/22) |
brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
brainstem | heterozygote | Section images | 100% (2/2) | 0.41% (2/490) |
brown adipose tissue | heterozygote | Section images | 0% (0/2) | 0% (0/588) |
cartilage tissue | heterozygote | Section images | 0% (0/2) | 0.22% (1/454) |
cecum | heterozygote | Section images | 100% (2/2) | 7.75% (22/284) |
External links
No external links available for Churc1.
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Churc1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Churc1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Churc1tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Churc1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
Churc1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |