Cog2 | component of oligomeric golgi complex 2

GeneMGI:1923582Synonyms: 2700012E02Rik, Cog2, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Mortality/aging

17 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

decreased circulating aspartate transaminase level1 supporting datasetCog2tm1a(KOMP)WtsiheterozygoteEarly adult1.04x10-7 
preweaning lethality, complete penetrance1 supporting datasetCog2tm1a(KOMP)WtsihomozygoteEarly adultN/A * 
increased circulating free fatty acids level1 supporting datasetCog2tm1a(KOMP)WtsiheterozygoteEarly adult9.85x10-5 
decreased body weight2 supporting datasetsCog2tm1a(KOMP)WtsiheterozygoteEarly adult6.47x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cog2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Cog2tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Cog2tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cog2tm3a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cog2tm42369(L1L2_Pgk_PM)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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