Gene: Cyrib

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased exploration in new environment Cyribtm1b(KOMP)Wtsi HET Early adult 1.87×10-05
abnormal embryo size Cyribtm1b(KOMP)Wtsi HOM E15.5 0.00
decreased circulating sodium level Cyribtm1b(KOMP)Wtsi HET Early adult 3.93×10-07
preweaning lethality, incomplete penetrance Cyribtm1b(KOMP)Wtsi HOM Early adult 0.00
increased circulating potassium level Cyribtm1b(KOMP)Wtsi HET Early adult 8.37×10-05
male infertility Cyribtm1b(KOMP)Wtsi HOM Early adult 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1  (1/65) N/A
Brain 2  (6/506) N/A
Central nervous system ganglion 1  (1/74) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507) N/A
Eye 2  (1/506) N/A
Foot 2  (1/506) N/A
Forebrain 2  (1/506) N/A
Forelimb 2  (1/506) N/A
Gut 1  (1/60)  (1/2) N/A
Hand 2  (1/506) N/A
Head 2  (5/506) N/A
Heart 2  (1/506) N/A
Hindbrain 2  (6/506) N/A
Hindlimb 2  (1/506) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506) N/A
Nose 1  (1/76) N/A
Oral cavity 2  (1/504) N/A
Chorioallantoic placenta 1  (7/39)  (1/2) N/A
Skeleton 1  (1/76) N/A
Skin 2  (1/506) N/A
Spinal cord 1  (1/73) N/A
Tail 2  (1/506) N/A
Tail somite 2  (1/506) N/A
Trachea 1  (1/60) N/A
Urinary system 1  (1/60) N/A

 Associated Images

Eye Morphology: Images Ophthalmoscopy
30 Images
Immunophenotyping: Panel A FCS file(s)
4 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
13 Images
Gross Pathology and Tissue Collection
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images
Immunophenotyping: Panel B FCS file(s)
4 Images
X-ray: XRay Images Skull Lateral Orientation
13 Images
Histopathology
5 Images
X-ray: XRay Images Whole Body Dorso Ventral
13 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Brain - MPATH diagnostic term hydrocephalus Cyribtm1b(KOMP)Wtsi HET Early adult
Spleen - hyperplasia Cyribtm1b(KOMP)Wtsi HOM Early adult
Spleen - hyperplasia Cyribtm1b(KOMP)Wtsi HET Early adult
Eye with optic nerve - developmental and structural abnormality Cyribtm1b(KOMP)Wtsi HOM Early adult
Brain - process of degenerative change Cyribtm1b(KOMP)Wtsi HET Early adult
Eye with optic nerve - developmental and structural abnormality Cyribtm1b(KOMP)Wtsi HET Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cyribtm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Cyribtm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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