Gene: Fam49b

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, incomplete penetrance Fam49btm1b(KOMP)Wtsi HOM n/a 0.00
decreased body length Fam49btm1b(KOMP)Wtsi HET postnatal 9.86×10-05
edema Fam49btm1b(KOMP)Wtsi HOM embryonic day 15.5 0.00
male infertility Fam49btm1b(KOMP)Wtsi HOM postpartum stage 0.00
decreased circulating sodium level Fam49btm1b(KOMP)Wtsi HET postnatal 3.21×10-05

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1  (1/51) N/A
Brain 2  (6/485) N/A
Central nervous system ganglion 1  (1/51) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Gut 1  (1/50)  (1/2) N/A
Hand 2  (1/485) N/A
Head 2  (5/485) N/A
Heart 2  (1/485)  (1/3) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 1  (1/51) N/A
Oral cavity 2  (1/485) N/A
1  (7/25)  (1/2) N/A
Skeleton 1  (1/51) N/A
Skin 2  (1/485) N/A
Spinal cord 1  (1/50) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A
Trachea 1  (1/50) N/A
Urinary system 1  (1/50) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
4 Images
X-ray: XRay Images Dorso Ventral
13 Images
X-ray: XRay Images Skull Lateral Orientation
13 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images
X-ray: XRay Images Lateral Orientation
13 Images
Eye Morphology: Images Ophthalmoscopy
30 Images
Histopathology
5 Images
Gross Pathology and Tissue Collection
14 Images
Combined SHIRPA and Dysmorphology
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - developmental and structural abnormality Fam49btm1b(KOMP)Wtsi HOM postnatal
Brain - MPATH diagnostic term hydrocephalus Fam49btm1b(KOMP)Wtsi HET postnatal
Eye with optic nerve - developmental and structural abnormality Fam49btm1b(KOMP)Wtsi HET postnatal
Spleen - hyperplasia Fam49btm1b(KOMP)Wtsi HOM postnatal
Brain - process of degenerative change Fam49btm1b(KOMP)Wtsi HET postnatal
Spleen - hyperplasia Fam49btm1b(KOMP)Wtsi HET postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Fam49btm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Fam49btm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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