The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases associated to Tsen54 by orthology or direct annotation.
The table below shows human diseases predicted to be associated to Tsen54 by phenotypic similarity.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Tsen54.
There are 1 publication which use IMPC produced mice or data.
|Title||Journal||IMPC Allele||PubMed ID|
|Three-dimensional microCT imaging of murine embryonic development from immediate post-implantation to organogenesis: application for phenotyping analysis of early embryonic lethality in mutant animals.||Mammalian genome : official journal of the International Mammalian Genome Society (November 2017)||Tsen54tm1a(EUCOMM)Wtsi||29170794|
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|MGI Allele||Allele Type||Produced|
|Tsen54tm1(KOMP)Vlcg||Reporter-tagged deletion allele (with selection cassette)||Targeting vectors, ES Cells|
|Tsen54tm1a(EUCOMM)Wtsi||KO first allele (reporter-tagged insertion with conditional potential)||Targeting vectors, ES Cells|
|Tsen54tm2a(EUCOMM)Wtsi||KO first allele (reporter-tagged insertion with conditional potential)||Targeting vectors, ES Cells|