The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Inka2.
There are 2 publications which use IMPC produced mice or data.
|Title||Journal||IMPC Allele||PubMed ID|
|Inka2 expression in smooth muscle cells and its involvement in cell migration.||Biochemical and biophysical research communications (December 2022)||Inka2tm1a(KOMP)Wtsi Inka2tm1b(KOMP)Wtsi||36586159|
|Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development.||PLoS genetics (October 2022)||Inka2tm1a(KOMP)Wtsi||PMC9612522|
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
|MGI Allele||Allele Type||Produced|
|Inka2tm1e(KOMP)Wtsi||Targeted, non-conditional allele||ES Cells|
|Inka2tm1a(KOMP)Wtsi||KO first allele (reporter-tagged insertion with conditional potential)||Mice, Targeting vectors, ES Cells|