Gene Summary

inka box actin regulator 2
6530418L21Rik,  Fam212b,  Inka2

IMPC Data Collections

IMPC Phenotype Summary

Not Significant
Not tested


The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.


XRay Images Skull Lateral Orientation

4 Images

DSS Histology


8 Images

Eye Morphology

Images Slit Lamp

5 Images


XRay Images Whole Body Lateral Orientation

4 Images

Anti-nuclear antibody assay


6 Images


XRay Images Whole Body Dorso Ventral

4 Images


XRay Images Forepaw

4 Images


XRay Images Skull Dorso Ventral Orientation

4 Images

Ear epidermis immunophenotyping


12 Images

Human diseases caused by Inka2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.
No human diseases associated to this gene by phenotypic similarity.


Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Inka2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Inka2.

There are 2 publications which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
Inka2 expression in smooth muscle cells and its involvement in cell migration. Biochemical and biophysical research communications (December 2022) Inka2tm1a(KOMP)Wtsi Inka2tm1b(KOMP)Wtsi 36586159
Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development. PLoS genetics (October 2022) Inka2tm1a(KOMP)Wtsi PMC9612522

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Inka2tm1e(KOMP)Wtsi Targeted, non-conditional allele ES Cells
Inka2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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