Gene Summary

Name:
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Synonyms:
Depdc2,  C030045D06Rik,  6230420N16Rik

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
thin ventricular wall Prex2em1(IMPC)Bay HOM Early adult 4.38×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Eye Morphology

VIP of right fundus

15 Images

X-ray

XRay Images Whole Body Dorso Ventral

9 Images

Eye Morphology

VIP of left eye

15 Images

X-ray

XRay Images Skull Lateral Orientation

10 Images

Eye Morphology

VIP of left fundus

15 Images

X-ray

XRay Images Forepaw

10 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

10 Images

X-ray

XRay Images Whole Body Lateral Orientation

10 Images

Eye Morphology

VIP of right eye

15 Images

Human diseases caused by Prex2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Prex2 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Diabetes Mellitus, Transient Neonatal, 2
Type II diabetes mellitus, Transient neonatal diabetes mellitus OMIM:610374
Type 2 Diabetes Mellitus
Insulin resistance, Type II diabetes mellitus OMIM:125853
Maturity-Onset Diabetes Of The Young, Type 7
Maturity-onset diabetes of the young, Type II diabetes mellitus OMIM:610508
Maturity-Onset Diabetes Of The Young, Type 4
Maturity-onset diabetes of the young, Type II diabetes mellitus OMIM:606392
Type 1 Diabetes Mellitus 15
Type I diabetes mellitus, Diabetes mellitus OMIM:601666
Maturity-Onset Diabetes Of The Young, Type 2
Maturity-onset diabetes of the young OMIM:125851
Type 1 Diabetes Mellitus 2
Type I diabetes mellitus OMIM:125852
Maturity-Onset Diabetes Of The Young, Type 9
Maturity-onset diabetes of the young OMIM:612225
Maturity-Onset Diabetes Of The Young, Type 6
Maturity-onset diabetes of the young OMIM:606394
Type 1 Diabetes Mellitus 20
Type I diabetes mellitus OMIM:612520
Type 1 Diabetes Mellitus 6
Diabetes mellitus OMIM:601941
Type 1 Diabetes Mellitus 10
Diabetes mellitus OMIM:601942
Pancreatic Beta Cell Agenesis With Neonatal Diabetes Mellitus
Neonatal insulin-dependent diabetes mellitus OMIM:600089
Acanthosis Nigricans With Muscle Cramps And Acral Enlargement
Insulin resistance OMIM:200170
Maturity-Onset Diabetes Of The Young, Type 3
Maturity-onset diabetes of the young, Hyperglycemia, Type II diabetes mellitus OMIM:600496
Maturity-Onset Diabetes Of The Young, Type 1
Maturity-onset diabetes of the young OMIM:125850
Maturity-Onset Diabetes Of The Young, Type 10
Diabetic ketoacidosis, Diabetes mellitus, Maturity-onset diabetes of the young, Hyperglycemia OMIM:613370
Diabetes Mellitus, Ketosis-Prone
Insulin resistance, Diabetes mellitus OMIM:612227
Hyperinsulinism Due To Insr Deficiency
Hyperinsulinemic hypoglycemia, Hypoglycemia, Recurrent hypoglycemia, Insulin resistance, Fasting ... ORPHA:263458
Hyperproinsulinemia
Hyperinsulinemia, Hyperglycemia OMIM:616214
Insulin Autoimmune Syndrome
Hyperinsulinemic hypoglycemia, Fasting hypoglycemia, Nonketotic hypoglycemia, Insulin resistance,... ORPHA:411593
Short Stature Due To Primary Acid-Labile Subunit Deficiency
Insulin resistance ORPHA:140941
Glycogen Storage Disease 0, Liver
Neonatal hypoglycemia, Postprandial hyperglycemia, Fasting hypoglycemia OMIM:240600
Hyperinsulinemic Hypoglycemia, Familial, 3
Hypoglycemic seizures, Diabetes mellitus, Hyperinsulinemic hypoglycemia OMIM:602485
Optic Atrophy--Spastic Paraplegia Syndrome
Abnormal oral glucose tolerance OMIM:311100
Diabetes Mellitus, Transient Neonatal, 1
Hyperglycemia, Transient neonatal diabetes mellitus OMIM:601410
Multiple Symmetric Lipomatosis
Insulin resistance ORPHA:2398
3-Hydroxy-3-Methylglutaryl-Coa Synthase Deficiency
Hypoglycemia ORPHA:35701
Hypogonadism, Male, With Mental Retardation And Skeletal Anomalies
Glucose intolerance, Hyperglycemia OMIM:307500
RCAD (renal cysts and diabetes)
Diabetes mellitus DECIPHER:47
Preaxial Hallucal Polydactyly
Diabetes mellitus OMIM:601759
Cortisone Reductase Deficiency 2
Insulin resistance OMIM:614662
Diabetes Mellitus, Transient Neonatal, 3
Hyperglycemia, Maternal diabetes, Transient neonatal diabetes mellitus OMIM:610582
Diabetes Mellitus, Permanent Neonatal, 4
Diabetic ketoacidosis, Type I diabetes mellitus, Hyperglycemia OMIM:618858
Cranial Nerves, Recurrent Paresis Of
Diabetes mellitus OMIM:218200
Maturity-Onset Diabetes Of The Young, Type 13
Diabetes mellitus, Hyperglycemia, Maturity-onset diabetes of the young, Maternal diabetes OMIM:616329
Hyperinsulinemic Hypoglycemia, Familial, 7
Hypoglycemic seizures, Hypoglycemia, Hyperinsulinemia, Hyperinsulinemic hypoglycemia OMIM:610021
Familial Partial Lipodystrophy, Köbberling Type
Insulin resistance, Diabetes mellitus, Hyperinsulinemia ORPHA:79084
Ataxia, Sensory, 1, Autosomal Dominant
Abnormal vestibulo-ocular reflex, Gait instability, worse in the dark, Impaired distal propriocep... OMIM:608984
Diabetes Mellitus, Permanent Neonatal, 1
Type I diabetes mellitus, Diabetes mellitus, Hyperglycemia OMIM:606176
Morbid Obesity And Spermatogenic Failure
Insulin resistance, Type II diabetes mellitus OMIM:615703
Transient Neonatal Diabetes Mellitus
Maturity-onset diabetes of the young, Maternal diabetes, Hypoinsulinemia, Hyperglycemia, Transien... ORPHA:99886
Maturity-Onset Diabetes Of The Young, Type 8, With Exocrine Dysfunction
Maturity-onset diabetes of the young, Hyperglycemia OMIM:609812
Insulinomatosis And Diabetes Mellitus
Hyperinsulinemic hypoglycemia, Type II diabetes mellitus, Impaired glucose tolerance OMIM:147630
Lipodystrophy, Familial Partial, Type 4
Insulin resistance, Insulin-resistant diabetes mellitus OMIM:613877
Acanthosis Nigricans-Insulin Resistance-Muscle Cramps-Acral Enlargement Syndrome
Insulin resistance, Insulin-resistant diabetes mellitus ORPHA:90301
Cone-Rod Synaptic Disorder Syndrome, Congenital Nonprogressive
Hyperglycemia OMIM:618970
Lipodystrophy, Familial Partial, Type 3
Hyperinsulinemia, Maternal diabetes, Hyperglycemia, Type II diabetes mellitus, Insulin resistance... OMIM:604367
Type 1 Diabetes Mellitus
Diabetes mellitus, Hyperglycemia OMIM:222100
Maturity-Onset Diabetes Of The Young, Type 14
Diabetes mellitus, Maturity-onset diabetes of the young OMIM:616511
Coronary Artery Disease, Autosomal Dominant 2
Glucose intolerance, Type II diabetes mellitus, Impaired glucose tolerance OMIM:610947
Acquired Partial Lipodystrophy
Insulin resistance ORPHA:79087
Body Mass Index Quantitative Trait Locus 19
Insulin resistance, Hyperinsulinemia OMIM:617885
Diabetes Mellitus, Permanent Neonatal, 2
Type I diabetes mellitus, Hyperglycemia OMIM:618856
Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities
Hyperinsulinemia, Fasting hypoglycemia, Hyperglycemia, Diabetic ketoacidosis, Hypoglycemia, Postp... OMIM:262190
Lipodystrophy, Congenital Generalized, Type 3
Insulin resistance, Diabetes mellitus OMIM:612526
Osteogenesis Imperfecta, Type Xxiii
Insulin resistance OMIM:620639
Diabetes Mellitus, Permanent Neonatal, 3
Glycosuria, Type I diabetes mellitus, Hyperglycemia OMIM:618857
Diabetes And Deafness, Maternally Inherited
Hyperglycemia, Type II diabetes mellitus OMIM:520000
Lipodystrophy, Familial Partial, Type 6
Insulin resistance, Diabetes mellitus OMIM:615980
Akt2-Related Familial Partial Lipodystrophy
Insulin resistance, Insulin-resistant diabetes mellitus ORPHA:79085
Hypertriglyceridemia 1
Glucose intolerance OMIM:145750
Placental Insufficiency
Insulin resistance ORPHA:439167
Mody
Neonatal hypoglycemia, Hypoinsulinemia, Glycosuria, Hyperglycemia, Transient neonatal diabetes me... ORPHA:552
Lipodystrophy, Familial Partial, Type 1
Hyperglycemia, Insulin-resistant diabetes mellitus OMIM:608600
Microcephalic Primordial Dwarfism-Insulin Resistance Syndrome
Insulin-resistant diabetes mellitus ORPHA:436182
Spastic Tetraplegia And Axial Hypotonia, Progressive
Cerebellar atrophy, Ataxia, Exaggerated startle response OMIM:618598
Severe Neurodegenerative Syndrome With Lipodystrophy
Insulin resistance, Hyperinsulinemia ORPHA:363400
Stiff Person Spectrum Disorder
Difficulty walking, Exaggerated startle response, Falls ORPHA:3198
Insulin-Resistance Syndrome Type B
Hyperinsulinemia, Hyperinsulinemic hypoglycemia, Fasting hypoglycemia, Glycosuria, Hyperglycemia,... ORPHA:2298
Neurodevelopmental Disorder With Cerebellar Atrophy And With Or Without Seizures
Truncal titubation, Tremor, Cerebellar atrophy, Exaggerated startle response, Gait ataxia, Abnorm... OMIM:618056
Mandibular Hypoplasia, Deafness, Progeroid Features, And Lipodystrophy Syndrome
Insulin resistance, Diabetes mellitus OMIM:615381
Spastic Paraplegia-Optic Atrophy-Neuropathy Syndrome
Impaired vibration sensation in the lower limbs, Difficulty walking, Exaggerated startle response ORPHA:320406
Pparg-Related Familial Partial Lipodystrophy
Insulin resistance, Diabetes mellitus, Maternal diabetes, Insulin-resistant diabetes mellitus ORPHA:79083
Glycogen Storage Disease Due To Hepatic Glycogen Synthase Deficiency
Glycosuria, Ketotic hypoglycemia, Postprandial hyperglycemia ORPHA:2089
Lipe-Related Familial Partial Lipodystrophy
Insulin resistance, Insulin-resistant diabetes mellitus ORPHA:435660
Leukodystrophy, Hypomyelinating, 13
Failure to thrive, Ataxia, Exaggerated startle response OMIM:616881
Seckel Syndrome 10
Glucose intolerance, Impaired glucose tolerance, Glycosuria, Insulin resistance, Diabetes mellitus OMIM:617253
Intellectual Developmental Disorder, Autosomal Recessive 54
Exaggerated startle response OMIM:617028
Cerebrooculofacioskeletal Syndrome 1
Insulin resistance OMIM:214150
Mandibuloacral Dysplasia
Insulin resistance, Hyperinsulinemia, Glucose intolerance, Insulin-resistant diabetes mellitus ORPHA:2457
Neuropathy, Hereditary Motor And Sensory, Okinawa Type
Hyperglycemia OMIM:604484
Neurodevelopmental Disorder With Or Without Seizures And Gait Abnormalities
Chorea, Failure to thrive, Inability to walk, Exaggerated startle response OMIM:617864
Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency
Insulin resistance, Hypoglycemia ORPHA:73272
Short Syndrome
Insulin resistance, Glucose intolerance, Hyperglycemia, Insulin-resistant diabetes mellitus OMIM:269880
Congenital Generalized Lipodystrophy
Insulin resistance, Diabetes mellitus, Hyperinsulinemia ORPHA:528
Familial Partial Lipodystrophy, Dunnigan Type
Insulin resistance, Diabetes mellitus ORPHA:2348
Developmental And Epileptic Encephalopathy 68
Failure to thrive, Exaggerated startle response OMIM:618201
Spastic Paraplegia, Optic Atrophy, And Neuropathy
Inability to walk, Exaggerated startle response OMIM:609541
Aromatic L-Amino Acid Decarboxylase Deficiency
Torticollis, Oculogyric crisis, Athetosis, Blepharospasm, Limb dystonia, Exaggerated startle resp... OMIM:608643
Short Syndrome
Insulin resistance, Diabetes mellitus ORPHA:3163
Rabson-Mendenhall Syndrome
Fasting hypoglycemia, Impaired glucose tolerance, Diabetic ketoacidosis, Insulin resistance, Fast... ORPHA:769
Thalidomide Embryopathy
Insulin resistance ORPHA:3312
Neurodevelopmental Disorder With Speech Impairment And With Or Without Seizures
Inability to walk, Exaggerated startle response OMIM:620114
Acquired Generalized Lipodystrophy
Insulin resistance, Hyperinsulinemia, Insulin-resistant diabetes mellitus ORPHA:79086
Familial Multiple Lipomatosis
Insulin resistance ORPHA:199276
Dopamine Beta-Hydroxylase Deficiency
Insulin resistance, Hypoglycemia, Hyperinsulinemia ORPHA:230
Gm2 Gangliosidosis, Ab Variant
Chorea, Dystonia, Exaggerated startle response ORPHA:309246
Hypokalemic Periodic Paralysis
Postprandial hyperglycemia ORPHA:681
Silver-Russell Syndrome
Insulin resistance, Recurrent hypoglycemia ORPHA:813
Abdominal Obesity-Metabolic Syndrome 3
Hyperglycemia, Type II diabetes mellitus OMIM:615812
Hyperekplexia-Epilepsy Syndrome
Exaggerated startle response ORPHA:163985
Marbach-Rustad Progeroid Syndrome
Insulin resistance OMIM:619322
Combined Oxidative Phosphorylation Deficiency 54
Hyperglycemia OMIM:619737
Werner Syndrome
Insulin resistance, Type II diabetes mellitus ORPHA:902
Neurodegeneration With Developmental Delay, Early Respiratory Failure, Myoclonic Seizures, And Brain Abnormalities
Inferior cerebellar vermis hypoplasia, Tremor, Cerebellar atrophy, Exaggerated startle response, ... OMIM:620327
Pura-Related Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome Due To A Point Mutation
Dystonia, Ataxia, Exaggerated startle response, Broad-based gait ORPHA:438216
Cole Disease
Hyperglycemia OMIM:615522
Monosomy 13Q34
Insulin resistance ORPHA:96168
Bardet-Biedl Syndrome 9
Hyperglycemia OMIM:615986
Short Stature, Microcephaly, And Endocrine Dysfunction
Insulin resistance, Diabetes mellitus OMIM:616541
Lipodystrophy, Congenital Generalized, Type 4
Insulin resistance, Hyperinsulinemia OMIM:613327
Acth-Independent Macronodular Adrenal Hyperplasia 2
Hyperglycemia OMIM:615954
Donohue Syndrome
Hyperinsulinemia, Hyperglycemia, Postprandial hyperglycemia, Fasting hypoglycemia OMIM:246200
Whipple Disease
Insulin resistance ORPHA:3452
Combined Oxidative Phosphorylation Deficiency 58
Difficulty walking, Cerebellar atrophy, Exaggerated startle response, Gait ataxia, Ataxia OMIM:620451
Tay-Sachs Disease
Inability to walk, Tremor, Cerebellar atrophy, Gait disturbance, Exaggerated startle response, Dy... ORPHA:845
Mitochondrial Complex Iii Deficiency, Nuclear Type 6
Hypoglycemia, Hyperglycemia OMIM:615453
Greig Cephalopolysyndactyly Syndrome
Hyperglycemia OMIM:175700
Mandibuloacral Dysplasia With Type B Lipodystrophy
Hyperinsulinemia, Hyperglycemia, Glucose intolerance, Insulin-resistant diabetes mellitus OMIM:608612
Autosomal Semi-Dominant Severe Lipodystrophic Laminopathy
Insulin resistance, Diabetes mellitus ORPHA:280365
Mandibuloacral Dysplasia With Type B Lipodystrophy
Insulin resistance ORPHA:90154
Mandibuloacral Dysplasia With Type A Lipodystrophy
Insulin resistance ORPHA:90153
Gm2-Gangliosidosis, Ab Variant
Chorea, Dystonia, Exaggerated startle response OMIM:272750
Developmental And Epileptic Encephalopathy 8
Exaggerated startle response OMIM:300607
Fanconi-Bickel Syndrome
Fasting hypoglycemia, Impaired glucose tolerance, Glycosuria, Diabetes mellitus, Postprandial hyp... ORPHA:2088
Aromatase Deficiency
Insulin resistance, Type II diabetes mellitus ORPHA:91
Silver-Russell Syndrome Due To Maternal Uniparental Disomy Of Chromosome 7
Insulin resistance, Fasting hypoglycemia ORPHA:96182
Sandhoff Disease
Ataxia, Impaired temperature sensation, Exaggerated startle response OMIM:268800
Hyperekplexia 2
Exaggerated startle response OMIM:614619
Bardet-Biedl Syndrome 1
Insulin resistance, Diabetes mellitus OMIM:209900
Hyperekplexia 3
Exaggerated startle response OMIM:614618
Mitchell-Riley Syndrome
Diabetes mellitus, Hyperglycemia OMIM:615710
Dend Syndrome
Hyperglycemia ORPHA:79134
Asparagine Synthetase Deficiency
Cerebellar vermis hypoplasia, Tremor, Exaggerated startle response, Dilated fourth ventricle, Fai... OMIM:615574
Leprechaunism
Hyperinsulinemia, Fasting hypoglycemia, Insulin resistance, Postprandial hyperglycemia, Recurrent... ORPHA:508
Gitelman Syndrome
Maternal diabetes, Type II diabetes mellitus, Diabetic ketoacidosis, Insulin resistance, Type I d... ORPHA:358
Bloom Syndrome
Insulin resistance, Diabetes mellitus ORPHA:125
Stiff-Person Syndrome
Opisthotonus, Exaggerated startle response OMIM:184850
Lipodystrophy, Familial Partial, Type 2
Hyperinsulinemia, Hyperglycemia, Type II diabetes mellitus, Insulin-resistant diabetes mellitus OMIM:151660
Necrotizing Enterocolitis
Hyperglycemia, Abnormal glucose homeostasis ORPHA:391673
Tay-Sachs Disease
Exaggerated startle response OMIM:272800
Hyperekplexia 1
Exaggerated startle response OMIM:149400
Plaa-Associated Neurodevelopmental Disorder
Failure to thrive, Dystonia, Cerebellar cortical atrophy, Exaggerated startle response ORPHA:521426
Pancreatic And Cerebellar Agenesis
Hypoglycemia, Diabetes mellitus, Hyperglycemia OMIM:609069
Symptomatic Form Of Hfe-Related Hemochromatosis
Diabetes mellitus, Hyperglycemia ORPHA:465508
Sudden Infant Death With Dysgenesis Of The Testes Syndrome
Exaggerated startle response OMIM:608800
Lipodystrophy, Familial Partial, Type 7
Insulin resistance, Type I diabetes mellitus, Glucose intolerance, Impaired glucose tolerance OMIM:606721
Developmental And Epileptic Encephalopathy 49
Cerebellar vermis hypoplasia, Dandy-Walker malformation, Exaggerated startle response OMIM:617281
Sandhoff Disease, Infantile Form
Exaggerated startle response ORPHA:309155
Beta-Ketothiolase Deficiency
Hypoglycemia, Hyperglycemia ORPHA:134
Acquired Aneurysmal Subarachnoid Hemorrhage
Hyperglycemia ORPHA:90065
Mandibuloacral Dysplasia With Type A Lipodystrophy
Hyperinsulinemia, Hyperglycemia, Impaired glucose tolerance, Insulin-resistant diabetes mellitus OMIM:248370
Isolated Permanent Neonatal Diabetes Mellitus
Glycosuria, Hyperglycemia, Neonatal insulin-dependent diabetes mellitus ORPHA:99885
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain And Eye Anomalies), Type A, 4
Cerebellar hypoplasia, Cerebellar cyst, Exaggerated startle response OMIM:253800
Steinert Myotonic Dystrophy
Insulin resistance, Diabetes mellitus, Hyperinsulinemia ORPHA:273
Isolated Sedoheptulokinase Deficiency
Postprandial hyperglycemia ORPHA:440713
Neurodevelopmental Disorder With Progressive Microcephaly, Spasticity, And Brain Anomalies
Failure to thrive, Exaggerated startle response OMIM:617527
Multiple Mitochondrial Dysfunctions Syndrome 7
Dystonia, Lethargy, Exaggerated startle response OMIM:620423
Bardet-Biedl Syndrome
Insulin resistance, Impaired fasting glucose, Type II diabetes mellitus ORPHA:110
Glycine Encephalopathy With Normal Serum Glycine
Exaggerated startle response OMIM:617301
Fanconi-Bickel Syndrome
Glycosuria, Postprandial hyperglycemia, Fasting hypoglycemia OMIM:227810
Alstrom Syndrome
Hyperinsulinemia, Hyperglycemia, Insulin-resistant diabetes mellitus OMIM:203800
Gm1 Gangliosidosis Type 1
Exaggerated startle response ORPHA:79255
Pyruvate Carboxylase Deficiency
Hypoglycemia, Hyperglycemia ORPHA:3008
Hutchinson-Gilford Progeria Syndrome
Insulin resistance ORPHA:740
Neurodevelopmental Disorder With Microcephaly, Epilepsy, And Hypomyelination
Cerebellar atrophy, Exaggerated startle response OMIM:618367
Atypical Werner Syndrome
Hyperinsulinemia, Glycosuria, Hyperglycemia, Type II diabetes mellitus, Fasting hyperinsulinemia,... ORPHA:79474
Mitochondrial Complex Iii Deficiency, Nuclear Type 1
Hypoglycemia, Hyperglycemia, Recurrent hypoglycemia OMIM:124000
Heart Defects, Congenital, And Other Congenital Anomalies
Glycosuria, Diabetes mellitus, Hyperglycemia OMIM:600001
Scorpion Envenomation
Glycosuria, Hyperglycemia ORPHA:466677
Thyrotoxic Periodic Paralysis
Postprandial hyperglycemia ORPHA:79102
Cognitive Impairment-Coarse Facies-Heart Defects-Obesity-Pulmonary Involvement-Short Stature-Skeletal Dysplasia Syndrome
Hyperglycemia ORPHA:444077
Pura-Related Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome
Dystonia, Inability to walk, Exaggerated startle response, Broad-based gait ORPHA:438213
Rapid-Onset Childhood Obesity-Hypothalamic Dysfunction-Hypoventilation-Autonomic Dysregulation Syndrome
Hyperglycemia ORPHA:293987
Mitochondrial Complex Iv Deficiency, Nuclear Type 5
Hypoglycemia, Hyperglycemia OMIM:220111
Pmm2-Cdg
Insulin resistance, Hyperinsulinemia ORPHA:79318
Alström Syndrome
Insulin resistance, Hyperinsulinemia, Type II diabetes mellitus ORPHA:64
Neurodevelopmental-Craniofacial Syndrome With Variable Renal And Cardiac Abnormalities
Exaggerated startle response OMIM:619522

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Prex2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Prex2.

No publications found that use IMPC mice or data for Prex2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Prex2tm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Prex2em1(IMPC)Bay Exon Deletion Mice
Prex2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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