Genes Phenotypes

Gene: Cul5

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Name
cullin 5
MGI ID
MGI:1922967
Synonyms
8430423K24Rik C030032G03Rik C330021I08Rik 4921514I20Rik VACM-1
Viability
Homozygous - Lethal
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (13) Measurements chart (191) All data table (706)
Expression & images (73) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating insulin level Cul5tm1.1(KOMP)Vlcg HET postnatal 1.22×10-06
embryonic lethality prior to organogenesis Cul5tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
enlarged heart Cul5tm1.1(KOMP)Vlcg HET postnatal 0.00
pale yolk sac Cul5tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
abnormal spleen morphology Cul5tm1.1(KOMP)Vlcg HET postnatal 0.00
abnormal embryo size Cul5tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
abnormal pericardium morphology Cul5tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
embryonic lethality prior to tooth bud stage Cul5tm1.1(KOMP)Vlcg HOM embryonic day 12.5 0.00
pallor Cul5tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
preweaning lethality, complete penetrance Cul5tm1.1(KOMP)Vlcg HOM n/a 0.00
enlarged spleen Cul5tm1.1(KOMP)Vlcg HET postnatal 0.00
embryonic growth retardation Cul5tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
decreased circulating creatinine level Cul5tm1.1(KOMP)Vlcg HET postnatal 7.13×10-08

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/383)  (1/2) N/A
Cerebellum 2 No  (1/2) N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127)  (1/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (1/2) N/A
Eye 2 No  (2/2) N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No  (1/2) N/A
Harderian gland 2 No  (2/2) N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (1/2) N/A
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No  (1/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (1/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (1/2) N/A
Olfactory lobe 2 No  (1/2) N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (1/2) N/A
Parathyroid gland 2 No  (1/2) N/A
Parotid gland 2 No N/A
Penis 2 No  (1/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Quadriceps 2 No  (1/2) N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (1/2) N/A
Spleen 2 No  (2/584)  (1/2) N/A
Stomach 2 No  (12/584)  (1/2) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No  (1/2) N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (1/2) N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127)  (1/2) N/A
Trachea 2 No  (1/2) N/A
Trigeminal V nerve 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Dorso Ventral
40 Images
X-ray: XRay Images Lateral Orientation
20 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Cul5tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Cul5tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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