Genes Phenotypes

Gene: Cul5

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Name
cullin 5
MGI ID
MGI:1922967
Synonyms
C330021I08Rik 4921514I20Rik VACM-1 8430423K24Rik C030032G03Rik
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (11) Measurements chart (190) All data table (443)
Expression & images (73) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal pericardium morphology Cul5tm1.1(KOMP)Vlcg HOM E9.5 0.00
abnormal spleen morphology Cul5tm1.1(KOMP)Vlcg HET Early adult 0.00
preweaning lethality, complete penetrance Cul5tm1.1(KOMP)Vlcg HOM Early adult 0.00
enlarged spleen Cul5tm1.1(KOMP)Vlcg HET Early adult 0.00
embryonic growth retardation Cul5tm1.1(KOMP)Vlcg HOM E9.5 0.00
decreased circulating creatinine level Cul5tm1.1(KOMP)Vlcg HET Early adult 7.23×10-08
enlarged heart Cul5tm1.1(KOMP)Vlcg HET Early adult 0.00
pale yolk sac Cul5tm1.1(KOMP)Vlcg HOM E9.5 0.00
decreased circulating insulin level Cul5tm1.1(KOMP)Vlcg HET Early adult 1.20×10-06
pallor Cul5tm1.1(KOMP)Vlcg HOM E9.5 0.00
abnormal embryo size Cul5tm1.1(KOMP)Vlcg HOM E9.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2)  Section images
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379)  (1/2)  Section images
Cerebellum 2 No  (1/2)  Section images
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Section images
Diaphragm 2 No N/A
Duodenum 2 No  (2/127)  (1/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (1/2)  Section images
Eye 2 No  (2/2)  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No  (1/2)  Section images
Harderian gland 2 No  (2/2)  Section images
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (1/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No  (1/2)  Section images
Lower urinary tract 2 No N/A
Lung 2 No  (1/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (1/2)  Section images
Olfactory lobe 2 No  (1/2)  Section images
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584)  (1/2)  Section images
Parathyroid gland 2 No  (1/2)  Section images
Parotid gland 2 No N/A
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Section images
Prostate gland 2 No  (12/584)  (1/2)  Section images
Quadriceps 2 No  (1/2)  Section images
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (1/2)  Section images
Spleen 2 No  (2/584)  (1/2)  Section images
Stomach 2 No  (12/584)  (1/2)  Section images
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No  (1/2)  Section images
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No  (1/2)  Section images
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127)  (1/2)  Section images
Trachea 2 No  (1/2)  Section images
Trigeminal V nerve 2 No  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2)  Section images
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
Unassigned Top Level MA (9)
adipose tissue (5)
Brown adipose tissue expression
MA:0000057
digestive system (15)
Cecum expression
MA:0000334
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (2)
Prostate gland expression
MA:0000404
immune system (2)
Spleen expression
MA:0000141
integumental system (4)
Skin expression
MA:0000151
musculoskeletal system (1)
Quadriceps expression
MA:0002363
nervous system (11)
Cerebellum expression
MA:0000198
postnatal mouse (70)
Adrenal gland expression
MA:0000116
reproductive system (11)
Epididymis expression
MA:0000397
respiratory system (5)
Lung expression
MA:0000415
sensory organ (6)
Eye expression
MA:0000261
set of connective tissues (5)
Brown adipose tissue expression
MA:0000057
trunk (45)
Adrenal gland expression
MA:0000116
urinary system (10)
Kidney expression
MA:0000368
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
79 Images
X-ray: XRay Images Whole Body Dorso Ventral
32 Images
X-ray: XRay Images Whole Body Lateral Orientation
16 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cul5tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Cul5tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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