Gene: Prpf6

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Name
pre-mRNA splicing factor 6
MGI ID
MGI:1922946
Synonyms
1190003A07Rik 2610031L17Rik ANT-1 U5-102K
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal mean corpuscular hemoglobin Prpf6tm1.1(KOMP)Vlcg HET Early adult 0.00
decreased circulating glucose level Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.51×10-05
abnormal behavior Prpf6tm1.1(KOMP)Vlcg HET Early adult 9.87×10-06
abnormal circulating glucose level Prpf6tm1.1(KOMP)Vlcg HET Early adult 2.69×10-09
abnormal bone structure Prpf6tm1.1(KOMP)Vlcg HET Early adult 4.12×10-07
abnormal anxiety-related response Prpf6tm1.1(KOMP)Vlcg HET Early adult 9.86×10-06
hyperactivity Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.32×10-05
decreased thigmotaxis Prpf6tm1.1(KOMP)Vlcg HET Early adult 9.48×10-05
preweaning lethality, complete penetrance Prpf6tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal body length Prpf6tm1.1(KOMP)Vlcg HET Early adult 6.10×10-11
abnormal bone mineral density Prpf6tm1.1(KOMP)Vlcg HET Early adult 2.43×10-06
abnormal bone mineralization Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.88×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589)  (2/2)  Section images
Aorta 2 No  (1/589)  (2/2)  Section images
Bone marrow 2 No  (2/2)  Section images
Brain 2 No  (3/589)  (2/2)  Section images
Brainstem 2 No  (2/589)  (2/2)  Section images
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (3/589)  (2/2)  Section images
Cerebral cortex 2 No  (2/589)  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (1/589)  (2/2)  Section images
Hippocampus 2 No  (3/589)  (2/2)  Section images
Hypothalamus 2 No  (2/589)  (2/2)  Section images
Kidney 2 No  (20/589)  (2/2)  Section images
Large intestine 2 No  (10/589)  (2/2)  Section images
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589)  (2/2)  Section images
Lymph node 2 No  (2/2)  Section images
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/589)  (2/2)  Section images
Ovary 2 No  (1/589)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/589)  (2/2)  Section images
Peripheral nervous system 2 No  (1/589)  (2/2)  Section images
Peyer's patch 2 No  (2/2)  Section images
Pituitary gland 2 No  (1/589) N/A
Prostate gland 2 No  (12/589) N/A
Skeletal muscle 2 No  (2/2)  Section images
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/589)  (2/2)  Section images
Spinal cord 2 No  (2/589)  (2/2)  Section images
Spleen 2 No  (2/589)  (2/2)  Section images
Stomach 2 No  (13/589)  (2/2)  Section images
Striatum 2 No  (3/589)  (2/2)  Section images
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (5/589)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (16/589)  (2/2)  Section images
Trachea 2 No  (2/589)  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (2/2) N/A
Dorsal root ganglion 1  (1/61) Image Only N/A
Ear 2  (1/506)  (2/2) N/A
Embryo 2  (1/507)  (2/2)  Wholemount images
Eye 2  (1/506)  (2/2) N/A
Foot 2  (1/506)  (2/2) N/A
Forebrain 2  (1/506)  (2/2) N/A
Forelimb 2  (1/506)  (2/2) N/A
Fronto-nasal process 1  (1/62) Image Only N/A
Hand 2  (1/505)  (2/2) N/A
Head 2  (5/506)  (2/2) N/A
Heart 2  (1/506)  (2/2) N/A
Hindbrain 2  (6/506)  (2/2) N/A
Hindlimb 2  (1/505)  (2/2) N/A
Liver 2  (1/506)  (2/2) N/A
Lung 2  (1/502)  (1/2) N/A
Mandibular process 2  (1/506)  (2/2) N/A
Maxillary process 2  (1/506)  (2/2) N/A
Midbrain 2  (1/506)  (2/2) N/A
Nose 1  (1/74)  (1/1) N/A
Oral cavity 2  (1/506)  (1/2) N/A
Skin 2  (1/506)  (2/2) N/A
Spinal cord 1  (1/73)  (1/1) N/A
Tail 2  (1/506)  (2/2) N/A
Tail somite 2  (1/506)  (2/2) N/A

 Associated Images

X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Adult LacZ: LacZ Images Section
45 Images
Sleep Wake: Wake state (bmp file)
6 Images
Embryo LacZ: LacZ images wholemount
8 Images
Eye Morphology: Images Slit Lamp
1 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

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MGI Allele Allele Type Produced
Prpf6tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Prpf6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Prpf6tm354908(L1L2_Bact_P) Targeting vectors

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