Gene: Prpf6

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Name
pre-mRNA splicing factor 6
MGI ID
MGI:1922946
Synonyms
1190003A07Rik U5-102K ANT-1 2610031L17Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hyperactivity Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.76×10-05
abnormal bone structure Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.56×10-08
decreased thigmotaxis Prpf6tm1.1(KOMP)Vlcg HET   Early adult 1.14×10-05
decreased bone mineral content Prpf6tm1.1(KOMP)Vlcg HET Early adult 6.67×10-11
decreased bone mineral density Prpf6tm1.1(KOMP)Vlcg HET Early adult 6.28×10-11
decreased circulating glucose level Prpf6tm1.1(KOMP)Vlcg HET Early adult 8.13×10-06
preweaning lethality, complete penetrance Prpf6tm1.1(KOMP)Vlcg HOM   Early adult 0.00
decreased body length Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.78×10-12
increased mean corpuscular hemoglobin Prpf6tm1.1(KOMP)Vlcg HET   Early adult 6.14×10-08
abnormal behavior Prpf6tm1.1(KOMP)Vlcg HET   Early adult 1.14×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Section images
Aorta 2 No  (1/583)  (2/2)  Section images
Bone marrow 2 No  (2/2)  Section images
Brain 2 No  (4/583)  (2/2)  Section images
Brainstem 2 No  (2/583)  (2/2)  Section images
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No  (1/583)  (2/2)  Section images
Cerebellum 2 No  (3/583)  (2/2)  Section images
Cerebral cortex 2 No  (2/583)  (2/2)  Section images
Epididymis 2 No  (18/132)  (1/2)  Section images
Esophagus 2 No  (7/407)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/583)  (2/2)  Section images
Hippocampus 2 No  (3/583)  (2/2)  Section images
Hypothalamus 2 No  (2/583)  (2/2)  Section images
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583)  (2/2)  Section images
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583)  (2/2)  Section images
Lymph node 2 No  (1/583)  (2/2)  Section images
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/583)  (2/2)  Section images
Ovary 2 No  (1/583)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/583)  (2/2)  Section images
Peripheral nervous system 2 No  (2/583)  (2/2)  Section images
Peyer's patch 2 No  (2/2)  Section images
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No  (2/2)  Section images
Skin 2 No  (1/583)  (2/2)  Section images
Small intestine 2 No  (9/583)  (2/2)  Section images
Spinal cord 2 No  (3/583)  (2/2)  Section images
Spleen 2 No  (3/583)  (2/2)  Section images
Stomach 2 No  (13/583)  (2/2)  Section images
Striatum 2 No  (3/583)  (2/2)  Section images
Submandibular gland 2 No  (2/130)  (2/2)  Section images
Testis 2 No  (6/583)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (1/583)  (2/2)  Section images
Thyroid gland 2 No  (17/583)  (2/2)  Section images
Trachea 2 No  (3/583)  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (2/2) N/A
1  (1/60) Image Only N/A
2  (1/505)  (2/2) N/A
2  (1/506)  (2/2)  Wholemount images
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
1  (1/61) Image Only N/A
2  (1/505)  (2/2) N/A
2  (5/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/503)  (2/2) N/A
2  (1/503)  (1/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
1  (1/75)  (1/1) N/A
2  (1/503)  (1/2) N/A
2  (1/505)  (2/2) N/A
1  (1/72)  (1/1) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
Original Image
Adult LacZ: LacZ Images Section
45 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Sleep Wake: Wake state (bmp file)
6 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Forepaw
9 Images
Electroretinography 2: Rod and cone PDF
4 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
5 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Prpf6tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Prpf6tm354908(L1L2_Bact_P) Targeting vectors
Prpf6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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