Gene: Prpf6

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Name
pre-mRNA splicing factor 6
MGI ID
MGI:1922946
Synonyms
1190003A07Rik 2610031L17Rik ANT-1 U5-102K
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased bone mineral density Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.44×10-06
decreased bone mineral content Prpf6tm1.1(KOMP)Vlcg HET Early adult 9.85×10-06
decreased thigmotaxis Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.88×10-05
increased circulating sodium level Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.87×10-05
decreased circulating glucose level Prpf6tm1.1(KOMP)Vlcg HET Early adult 5.34×10-07
increased mean corpuscular hemoglobin Prpf6tm1.1(KOMP)Vlcg HET Early adult 0.00
decreased body length Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.00×10-11
abnormal behavior Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.89×10-05
hyperactivity Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.50×10-05
preweaning lethality, complete penetrance Prpf6tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal bone structure Prpf6tm1.1(KOMP)Vlcg HET Early adult 1.81×10-07

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (3/590)  (2/2)  Section images
2 No  (1/590)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (3/590)  (2/2)  Section images
2 No  (2/590)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (3/590)  (2/2)  Section images
2 No  (2/590)  (2/2)  Section images
2 No  (18/134)  (1/2)  Section images
2 No  (7/415)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/590)  (2/2)  Section images
2 No  (3/590)  (2/2)  Section images
2 No  (2/590)  (2/2)  Section images
2 No  (20/590)  (2/2)  Section images
2 No  (10/590)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/590) N/A
2 No  (1/590)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/2)  Section images
2 No  (2/590)  (2/2)  Section images
2 No  (1/590)  (1/2)  Section images
2 No  (1/2)  Section images
2 No  (5/590)  (2/2)  Section images
2 No  (1/590)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/590) N/A
2 No  (12/590) N/A
2 No  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (9/590)  (2/2)  Section images
2 No  (2/590)  (2/2)  Section images
2 No  (2/590)  (2/2)  Section images
2 No  (13/590)  (2/2)  Section images
2 No  (3/590)  (2/2)  Section images
2 No  (2/132)  (2/2)  Section images
2 No  (5/590)  (1/2)  Section images
2 No  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (16/590)  (2/2)  Section images
2 No  (2/590)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/2)  Section images
2 No N/A
2 No  (2/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/506)  (2/2) N/A
1  (1/61) Image Only N/A
2  (1/506)  (2/2) N/A
2  (1/507)  (2/2)  Wholemount images
2  (1/506)  (2/2) N/A
2  (1/506)  (2/2) N/A
2  (1/506)  (2/2) N/A
2  (1/506)  (2/2) N/A
1  (1/62) Image Only N/A
2  (1/506)  (2/2) N/A
2  (5/506)  (2/2) N/A
2  (1/506)  (2/2) N/A
2  (6/506)  (2/2) N/A
2  (1/506)  (2/2) N/A
2  (1/504)  (2/2) N/A
2  (1/504)  (1/2) N/A
2  (1/506)  (2/2) N/A
2  (1/506)  (2/2) N/A
2  (1/506)  (2/2) N/A
1  (1/76)  (1/1) N/A
2  (1/504)  (1/2) N/A
2  (1/506)  (2/2) N/A
1  (1/73)  (1/1) N/A
2  (1/506)  (2/2) N/A
2  (1/506)  (2/2) N/A

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Original Image
Adult LacZ: LacZ Images Section
45 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Eye Morphology: Images Slit Lamp
1 Images
X-ray: XRay Images Forepaw
9 Images
Sleep Wake: Wake state (bmp file)
6 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Prpf6tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Prpf6tm354908(L1L2_Bact_P) Targeting vectors
Prpf6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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