Gene: Ppp1r35

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Name
protein phosphatase 1, regulatory subunit 35
MGI ID
MGI:1922853
Synonyms
2010011D20Rik 2010007H12Rik
Viability
Embryo viewer
N/A
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal sleep behavior Ppp1r35tm1.1(KOMP)Vlcg HET   Early adult 2.04×10-05
preweaning lethality, complete penetrance Ppp1r35tm1.1(KOMP)Vlcg HOM   Early adult 0.00
decreased circulating cholesterol level Ppp1r35tm1.1(KOMP)Vlcg HET Early adult 1.52×10-05
embryonic growth retardation Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
abnormal embryo turning Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
decreased circulating HDL cholesterol level Ppp1r35tm1.1(KOMP)Vlcg HET Early adult 3.36×10-07
abnormal embryo size Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
abnormal lens morphology Ppp1r35tm1.1(KOMP)Vlcg HET   Early adult 3.88×10-05
abnormal midbrain development Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
decreased circulating chloride level Ppp1r35tm1.1(KOMP)Vlcg HET Early adult 1.79×10-07
abnormal forebrain development Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
abnormal heart morphology Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
decreased circulating glucose level Ppp1r35tm1.1(KOMP)Vlcg HET Early adult 5.73×10-05
embryonic lethality prior to tooth bud stage Ppp1r35tm1.1(KOMP)Vlcg HOM   E12.5 0.00
abnormal tail bud morphology Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Section images
Aorta 2 No  (1/583)  (2/2)  Section images
Bone marrow 2 No  (2/2)  Section images
Brain 2 No  (4/583)  (2/2)  Section images
Brainstem 2 No  (2/583)  (2/2)  Section images
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No  (1/583)  (2/2)  Section images
Cerebellum 2 No  (3/583)  (2/2)  Section images
Cerebral cortex 2 No  (2/583)  (2/2)  Section images
Epididymis 2 No  (18/132)  (1/2)  Section images
Esophagus 2 No  (7/407)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/583)  (2/2)  Section images
Hippocampus 2 No  (3/583)  (2/2)  Section images
Hypothalamus 2 No  (2/583)  (2/2)  Section images
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583)  (2/2)  Section images
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583)  (2/2)  Section images
Lymph node 2 No  (1/583)  (2/2)  Section images
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/583)  (2/2)  Section images
Ovary 2 No  (1/583)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/583)  (2/2)  Section images
Peripheral nervous system 2 No  (2/583)  (2/2)  Section images
Peyer's patch 2 No  (2/2)  Section images
Pituitary gland 2 No  (1/583)  (2/2)  Section images
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No  (2/2)  Section images
Skin 2 No  (1/583)  (2/2)  Section images
Small intestine 2 No  (9/583)  (2/2)  Section images
Spinal cord 2 No  (3/583)  (2/2)  Section images
Spleen 2 No  (3/583)  (2/2)  Section images
Stomach 2 No  (13/583)  (2/2)  Section images
Striatum 2 No  (3/583)  (2/2)  Section images
Submandibular gland 2 No  (2/130)  (2/2)  Section images
Testis 2 No  (6/583)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (1/583)  (2/2)  Section images
Thyroid gland 2 No  (17/583)  (2/2)  Section images
Trachea 2 No  (3/583)  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (2/2) N/A
2  (1/60)  (1/2) N/A
2  (1/505)  (1/2) N/A
2  (1/506)  (2/2)  Wholemount images
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/61) Image Only N/A
2  (1/505)  (2/2) N/A
2  (5/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/503)  (1/2) N/A
2  (1/503) Image Only N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/75)  (2/2) N/A
2  (1/503) Image Only N/A
2  (1/505)  (2/2) N/A
2  (1/72)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A

 Associated Images

Original Image
Adult LacZ: LacZ Images Section
46 Images
Sleep Wake: Wake state (bmp file)
12 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
Eye Morphology: Images Ophthalmoscopy
2 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
X-ray: XRay Images Whole Body Lateral Orientation
11 Images
Gross Morphology Embryo E9.5
6 Images
X-ray: XRay Images Forepaw
11 Images
Embryo LacZ: LacZ images wholemount
8 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ppp1r35tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Ppp1r35tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Ppp1r35tm213349(L1L2_Bact_P) Targeting vectors

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