Gene: Ppp1r35

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Name
protein phosphatase 1, regulatory subunit 35
MGI ID
MGI:1922853
Synonyms
2010011D20Rik 2010007H12Rik
Embryo viewer
N/A
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal tail bud morphology Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
abnormal embryo size Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
embryonic growth retardation Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
abnormal embryo turning Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
preweaning lethality, complete penetrance Ppp1r35tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal embryo turning Ppp1r35tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal embryo size Ppp1r35tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal midbrain development Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
decreased circulating glucose level Ppp1r35tm1.1(KOMP)Vlcg HET Early adult 5.01×10-06
abnormal forebrain development Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
abnormal heart morphology Ppp1r35tm1.1(KOMP)Vlcg HOM E9.5 0.00
embryonic growth retardation Ppp1r35tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal lens morphology Ppp1r35tm1.1(KOMP)Vlcg HET Early adult 7.57×10-05
abnormal sleep behavior Ppp1r35tm1.1(KOMP)Vlcg HET Early adult 5.10×10-06
embryonic lethality prior to tooth bud stage Ppp1r35tm1.1(KOMP)Vlcg HOM E12.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (2/2) N/A
Bone marrow 2 No  (2/2)  Section images
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2)  Section images
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (1/2) N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2)  Section images
Peripheral nervous system 2 No  (2/2)  Section images
Peyer's patch 2 No  (2/2)  Section images
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2)  Section images
Spinal cord 2 No  (2/2)  Section images
Spleen 2 No  (2/584)  (2/2)  Section images
Stomach 2 No  (12/584)  (2/2)  Section images
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No  (2/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (2/2) N/A
Dorsal root ganglion 2  (1/57)  (1/2) N/A
Ear 2  (1/504)  (1/2) N/A
Embryo 2  (1/505)  (2/2)  Wholemount images
Eye 2  (1/504)  (2/2) N/A
Foot 2  (1/504)  (2/2) N/A
Forebrain 2  (1/504)  (2/2) N/A
Forelimb 2  (1/504)  (2/2) N/A
Fronto-nasal process 2  (1/58) Image Only N/A
Hand 2  (1/503)  (2/2) N/A
Head 2  (5/504)  (2/2) N/A
Heart 2  (1/504)  (2/2) N/A
Hindbrain 2  (6/504)  (2/2) N/A
Hindlimb 2  (1/503)  (2/2) N/A
Liver 2  (1/504)  (1/2) N/A
Lung 2  (1/500) Image Only N/A
Mandibular process 2  (1/504)  (2/2) N/A
Maxillary process 2  (1/504)  (2/2) N/A
Midbrain 2  (1/504)  (2/2) N/A
Nose 2  (1/70)  (2/2) N/A
Oral cavity 2  (1/504) Image Only N/A
Skin 2  (1/504)  (2/2) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 2  (1/504)  (2/2) N/A
Tail somite 2  (1/504)  (2/2) N/A

 Associated Images

Original Image
Adult LacZ: LacZ Images Section
20 Images
Embryo LacZ: LacZ images wholemount
4 Images
Gross Morphology Embryo E9.5
6 Images
Sleep Wake: Wake state (bmp file)
12 Images
Electroretinography 2: Rod and cone PDF
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
X-ray: XRay Images Forepaw
11 Images
Eye Morphology: Images Ophthalmoscopy
2 Images
X-ray: XRay Images Whole Body Dorso Ventral
11 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ppp1r35tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Ppp1r35tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Ppp1r35tm213349(L1L2_Bact_P) Targeting vectors

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