Gene: Oplah

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Name
5-oxoprolinase (ATP-hydrolysing)
MGI ID
MGI:1922725
Synonyms
N/A
Viability
N/A
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased startle reflex Oplahtm1b(KOMP)Wtsi HOM Early adult 2.79×10-05
abnormal lens morphology Oplahtm1b(KOMP)Wtsi HOM Early adult 2.15×10-09
cataract Oplahtm1b(KOMP)Wtsi HOM Early adult 6.28×10-10
decreased grip strength Oplahtm1b(KOMP)Wtsi HOM Early adult 6.63×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (2/584) N/A
Aorta 1 No N/A
Blood 1 No N/A
Bone 1 No N/A
Bone marrow 1 No N/A
Brain 1 Yes  (2/2)  Wholemount images
Brainstem 1 No N/A
Brown adipose tissue 1 No N/A
Cartilage tissue 1 No N/A
Cecum 1 No  (12/379) N/A
Cerebellum 1 No N/A
Cerebral cortex 1 No N/A
Chest bone 1 Yes  (1/2)  Wholemount images
Colon 1 No  (12/127)  (1/2)  Wholemount images
Cranium 1 No  (1/2)  Wholemount images
Diaphragm 1 No N/A
Epididymis 1 No  (18/134) N/A
Esophagus 1 No  (7/415) N/A
Eye 1 No N/A
Gall bladder 1 No N/A
Harderian gland 1 No N/A
Heart 1 No N/A
Hindlimb 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Kidney 1 Yes  (18/584)  (2/2)  Wholemount images
Large intestine 1 No  (10/584) N/A
Liver 1 No N/A
Lower urinary tract 1 No N/A
Lung 1 Yes  (2/2)  Wholemount images
Lymph node 1 No N/A
Main olfactory bulb 1 No N/A
Mammary gland 1 No N/A
Mesenteric lymph node 1 No N/A
Olfactory lobe 1 No N/A
Oral epithelium 1 No N/A
Ovary 1 No  (1/584) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/584) N/A
Parathyroid gland 1 No N/A
Parotid gland 1 No N/A
Penis 1 No N/A
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No N/A
Prostate gland 1 No  (12/584) N/A
Sciatic nerve 1 No N/A
Skeletal muscle 1 No N/A
Skin 1 No N/A
Small intestine 1 No  (9/584) N/A
Spinal cord 1 No N/A
Spleen 1 No  (2/584) N/A
Stomach 1 No  (12/584)  (1/2)  Wholemount images
Stomach pyloric region 1 No N/A
Striatum 1 No N/A
Sublingual gland 1 No N/A
Submandibular gland 1 No  (2/132)  (1/2)  Wholemount images
Testis 1 No  (2/584)  (1/2)  Wholemount images
Thymus 1 No  (1/2)  Wholemount images
Thyroid gland 1 No  (15/584) N/A
Tongue 1 No  (5/127) N/A
Trachea 1 No N/A
Trigeminal V nerve 1 No N/A
Urinary bladder 1 No N/A
Uterus 1 No N/A
Vagina 1 No N/A
Vas deferens 1 No  (15/388) N/A
Vascular system 1 No N/A
Vesicular gland 1 No N/A
White adipose tissue 1 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Adult LacZ: LacZ Images Wholemount
14 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Oplahtm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Oplahtm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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