Gene: Ascc2

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Name
activating signal cointegrator 1 complex subunit 2
MGI ID
MGI:1922702
Synonyms
2610034L15Rik ASC1p100 1700011I11Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased effector memory T-helper cell number Ascc2tm1a(EUCOMM)Wtsi HET   Early adult 1.32×10-06
long tibia Ascc2tm1b(EUCOMM)Wtsi HET Early adult 1.27×10-09
trunk curl Ascc2tm1a(EUCOMM)Wtsi HET   Early adult 1.07×10-06
preweaning lethality, complete penetrance Ascc2tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
decreased heart left ventricle size Ascc2tm1b(EUCOMM)Wtsi HET Early adult 1.05×10-06
enlarged spleen Ascc2tm1a(EUCOMM)Wtsi HET Early adult 0.00
embryonic lethality prior to organogenesis Ascc2tm1b(EUCOMM)Wtsi HOM   E9.5 0.00
preweaning lethality, complete penetrance Ascc2tm1a(EUCOMM)Wtsi HOM   Early adult 0.00
abnormal retinal inner nuclear layer morphology Ascc2tm1b(EUCOMM)Wtsi HET   Early adult 1.36×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Wholemount images
Aorta 2 No  (1/583)  (2/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583)  (2/2)  Wholemount images
Cecum 2 No  (12/371) N/A
Cerebellum 2 No  (3/583)  Wholemount images
Cerebral cortex 2 No  (2/583)  (2/2)  Wholemount images
Esophagus 2 No  (7/407)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583)  (2/2)  Wholemount images
Hippocampus 2 No  (3/583)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/583)  (2/2)  Wholemount images
Kidney 2 No  (21/583)  (2/2)  Wholemount images
Large intestine 2 No  (10/583)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/583)  (2/2)  Wholemount images
Lung 2 No  (2/583)  (2/2) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583)  (2/2)  Wholemount images
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/583)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/583)  (2/2)  Wholemount images
Parathyroid gland 2 No  (1/563)  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/583)  (1/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (2/2)  Wholemount images
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583)  (2/2)  Wholemount images
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583)  (2/2)  Wholemount images
Striatum 2 No  (3/583)  (2/2)  Wholemount images
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583)  Wholemount images
Trachea 2 No  (3/583)  (2/2)  Wholemount images
Trigeminal V nerve 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vas deferens 2 No  (15/382)  (1/2)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/60)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/73)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/506)  (2/2) N/A
2  (1/71)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/61)  (2/2) N/A
2  (1/59)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (5/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/58)  (2/2) N/A
2  (1/503)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/503)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/75)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/503)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/56)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/57)  (2/2) N/A
2  (1/75)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/72)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/59)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/59)  (2/2) N/A
2  (1/71)  (2/2) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
32 Images
X-ray: XRay Images Forepaw
32 Images
X-ray: XRay Images Skull Lateral Orientation
32 Images
X-ray: XRay Images Whole Body Lateral Orientation
32 Images
X-ray: XRay Images Whole Body Dorso Ventral
32 Images
Embryo LacZ: LacZ images wholemount
4 Images
Adult LacZ: LacZ Images Wholemount
15 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ascc2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Ascc2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells, Tissue
Ascc2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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