Gene: Tomm20l

Name
translocase of outer mitochondrial membrane 20-like
MGI ID
MGI:1922516
Synonyms
4930553D19Rik
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (816) Expression & images (45) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector gd cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw footpad size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw footpad size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Bulging eye HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Bulging eye HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia morphology HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell number HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell number HOM 10f:10m 0.441 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of B220+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Iris/Pupil HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Iris/Pupil HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout morphology HOM 10f:10m Fisher Exact Test framework 0.306 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Hematology / Mean cell hemoglobin concentration HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.101 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Hematology / Mean cell hemoglobin concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.670 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Kyphosis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Kyphosis HOM 9f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Lumbar processes HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Lumbar processes HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors morphology HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Indirect Calorimetry / Total food intake HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.330 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Fibula HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Fibula HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Shape of vertebrae HOM 10f:10m Fisher Exact Test framework 0.217 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Shape of vertebrae HOM 7f:7m Fisher Exact Test framework 0.465 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 5f:2m 0.223 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:3m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Trunk curl HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Body length HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.266 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Body length HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.911 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Cortical Bone Mineral Density HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Cortical Bone Mineral Density HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of DC HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Lens Opacity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Lens Opacity HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of mature NK cells HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / LDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.283 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / LDL-cholesterol HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.594 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte percentage HOM 10f:10m 0.410 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of B2 cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Vertebral Microradiography / Vertebral Height HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Vertebral Microradiography / Vertebral Height HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / CD8+CD44+CD62L- percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.198 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Zygomatic bone HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Zygomatic bone HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin colour HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair length HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Calcium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0602 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Calcium HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0689 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Shape of ribs HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Shape of ribs HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair length HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.150 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.179 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Macrophages - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00284 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00650 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail length HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail length HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Potassium HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0176 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Potassium HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0806 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Myeloid cells - % of CD45+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 5f:2m 0.000753 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:3m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Phosphorus HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00665 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Phosphorus HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.740 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Viability Primary Screen / Outcome HOM 45f:49m Supplied as data Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Viability Primary Screen / Outcome HOM 114f:121m Supplied as data Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of DC HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head bobbing/circling HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head bobbing/circling HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail colour HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.790 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / B1a cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Corneal vascularization HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Corneal vascularization HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Pattern HOM 9f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Triglycerides HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.423 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Triglycerides HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.577 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head size HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Hematology / Platelet count HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.120 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Hematology / Platelet count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.350 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Follicular B cells - % of B2 cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Transfer arousal HOM 10f:10m Fisher Exact Test framework 0.292 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Transfer arousal HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell number HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell number HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Position HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Position HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin colour HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average volume of LC HOM 3f:3m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Scoliosis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Scoliosis HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisor colour HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisor colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil percentage HOM 10f:10m 0.415 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Fusion of vertebrae HOM 7f:7m Fisher Exact Test framework 0.618 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Fusion of vertebrae HOM 10f:10m Fisher Exact Test framework 0.639 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Tibia HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Tibia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0542 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.117 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin appearance HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Lens HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Lens HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.162 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Grip Strength / Forelimb grip strength normalised against body weight HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.331 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail morphology HOM 10f:10m Fisher Exact Test framework 0.200 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Sodium HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.241 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Sodium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.296 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD3+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.948 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Femoral Microradiography / Femur Length HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Femoral Microradiography / Femur Length HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total B cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.216 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.431 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of NKT cells HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Corneal touch reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Corneal touch reflex HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Contact righting reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Contact righting reflex HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / HDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.522 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / HDL-cholesterol HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.722 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Persistence of hyaloid vascular system HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Persistence of hyaloid vascular system HOM 9f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Yield Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Yield Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Granulocytes - % of CD45+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Maxilla/Pre-maxilla HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Maxilla/Pre-maxilla HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of NK cellls HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Gait (inc. ataxia) HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Gait (inc. ataxia) HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Caudal processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Caudal processes HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total B2 cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head morphology HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Number of ribs right HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Number of ribs right HOM 7f:7m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total DC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Alpha-amylase HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.107 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Alpha-amylase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.241 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Iron HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.143 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Iron HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.582 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting Treg cells - % of Treg HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of B2 cells HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Magnesium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00390 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Magnesium HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.107 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Convulsions HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Convulsions HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasmacytoid DC - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte number HOM 10f:10m 0.0935 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Salmonella Challenge / Pre-Day 14 Death HOM 4f:0m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit fusion HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average branch length of LC HOM 3f:3m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of NK cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0667 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Grip Strength / Forelimb grip strength measurement mean HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.370 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of Treg HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance HOM 7f:7m Fisher Exact Test framework 0.0616 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Three-point Bend / Energy Dissipated Prior to Fracture HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Three-point Bend / Energy Dissipated Prior to Fracture HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI DSS Histology / Pre-Day 10 Death HOM 2f:2m - 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Femur HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Femur HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil number HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Free fatty acids HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.363 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Free fatty acids HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.729 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Cornea HOM 7f:7m Fisher Exact Test framework 0.467 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Cornea HOM 10f:10m Fisher Exact Test framework 0.498 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Germinal centre B cells - % of B2 cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ T helper cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ T helper cells - % of CD4+ T helper cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:3m 0.00509 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 5f:2m 0.450 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Eosinophil percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of B220+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0331 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.121 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Follicular B cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna position HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna position HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Hematology / Red blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.557 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Hematology / Red blood cell count HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.825 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit count HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / Mature B cell IgD+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0215 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Iris Pigmentation HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Iris Pigmentation HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Mature NK cells - % of lymphocytes HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin colour HOM 7f:7m Fisher Exact Test framework 0.0482 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin colour HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of cDC HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Granulocytes - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD4+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.894 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Startle response HOM 10f:10m Fisher Exact Test framework 0.0713 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Startle response HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Thoracic processes HOM 7f:7m Fisher Exact Test framework 0.651 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Thoracic processes HOM 10f:10m Fisher Exact Test framework 0.714 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Humerus HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Humerus HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell number HOM 10f:10m 0.419 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Total B cells - % of CD45+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0100 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0317 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of gd T cells HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Number of lumbar vertebrae HOM 7f:7m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Number of lumbar vertebrae HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Lordosis HOM 9f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Lordosis HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Eosinophils - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin colour HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of B2 cells HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Ulna HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Ulna HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Sacral processes HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Sacral processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD4- NKT cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair length HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector Treg cells - % of Treg HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total DC - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit count HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit count HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair presence HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia size HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Number of caudal vertebrae HOM 10f:10m 0.256 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Number of caudal vertebrae HOM 7f:7m 0.790 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NK cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Number of ribs left HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Number of ribs left HOM 7f:7m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail colour HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair length HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Area HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0831 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Area HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.914 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total NK cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of ab T cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of B2 cells HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell number HOM 10f:10m 0.406 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average roundness of LC HOM 3f:3m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit morphology HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ T helper cells - % of CD4+ T helper cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin colour HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of B220+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair presence HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit size HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 2 B cells - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Mature B cells (Hardy fraction F) - % of CD45+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ KLRG1+ alpha beta T cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Glucose HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.305 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Glucose HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.597 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-pro B cells (Hardy fraction A) - % of CD45+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Skull shape HOM 10f:10m Fisher Exact Test framework 0.385 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Skull shape HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Langerhans cell (LC) count HOM 3f:3m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Chloride HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.168 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Chloride HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.800 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Insulin Blood Level / Insulin HOM 10f:9m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.537 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Insulin Blood Level / Insulin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.796 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ mature NK cells - % of lymphocytes HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD25+ alpha beta regulatory T cell number HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean mass HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.418 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean mass HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.751 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Light Response HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Light Response HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Corneal opacity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Corneal opacity HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of cDC HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / Treg cell CD25+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.104 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Number of pelvic vertebrae HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Number of pelvic vertebrae HOM 7f:7m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Monocytes - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Shape of ribcage HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Shape of ribcage HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tremor HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tremor HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Hematology / White blood cell count HOM 10f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0993 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Hematology / White blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.146 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of B2 cells HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Alanine aminotransferase HOM 10f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.630 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Alanine aminotransferase HOM 7f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.902 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Eosinophils - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of NK cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Naive CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Creatinine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00397 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Creatinine HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.593 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Number of thoracic vertebrae HOM 7f:7m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Number of thoracic vertebrae HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD4- NKT cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / B1a cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Thickness (mm) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Thickness (mm) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Memory B cells - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Radius HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Radius HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Hematology / Mean platelet volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.131 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Hematology / Mean platelet volume HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.663 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / NKT cell percentage HOM 10f:10m 0.419 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Brachydactyly HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Brachydactyly HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting gd T cells - % of gd T cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total gd T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4- NKT cells - % of NKT cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Scapulae HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Scapulae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / Monocyte percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.135 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell number HOM 10f:10m 0.406 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD4+ T helper cells - % of CD4+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair presence HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Naive CD8+ T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit fusion HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of B2 cells HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of lymphocytes HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Retina (combined) HOM 7f:7m Not processed Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Retina (combined) HOM 9f:10m Not processed Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Polysyndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Polysyndactylism HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Hematology / Hematocrit HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.342 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Hematology / Hematocrit HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.679 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific total IgG HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.0668 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Memory B cells - % of B2 cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Immature B cells (Hardy fraction E) - % of CD45+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae shape HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Clow monocyte number HOM 10f:10m 0.406 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Creatine kinase HOM 10f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.564 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Creatine kinase HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.883 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ CD44+ CD62L- alpha beta effector T cell number HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Dilation HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Dilation HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of B220+ HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat mass HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0104 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat mass HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.435 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / KLRG1+ mature NK cell number HOM 10f:10m 0.415 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Three-point Bend / Stiffness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Three-point Bend / Stiffness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Thyroxine HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0292 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ Treg cells - % of Treg HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Transitional 1 B cells - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Indirect Calorimetry / Total water intake HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.781 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin colour HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail elevation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail elevation HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector NK cells - % of NK cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD8+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.121 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:3m 0.261 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 5f:2m 0.345 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw morphology HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4- NKT cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD11b-low cDC HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / B cell percentage HOM 10f:10m 0.419 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Clavicle HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Clavicle HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone B cells - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total Treg cells - % of CD4+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Spacing (mm) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Spacing (mm) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / NK cell percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.876 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4- NKT cells - % of CD4- NKT cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of GC cells HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Digit integrity HOM 10f:10m Fisher Exact Test framework 0.398 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Digit integrity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Marginal zone precursor B cells - % of B2 cells HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ NKT cells - % of NKT cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail length HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Total protein HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.199 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Total protein HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.404 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00316 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat/Body weight HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.396 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector gd T cells - % of gd T cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Number of cervical vertebrae HOM 7f:7m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Number of cervical vertebrae HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total B2 cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Eyelid closure HOM 7f:7m Fisher Exact Test framework 0.0909 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Eyelid closure HOM 10f:10m Fisher Exact Test framework 0.127 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Three-point Bend / Fracture Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Three-point Bend / Fracture Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ CD8+ T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte number HOM 10f:10m 0.0150 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / Granulocyte Gr1+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00513 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of CD45+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Gamma delta T cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Aspartate aminotransferase HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.820 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Aspartate aminotransferase HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.883 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of NK cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of lymphocytes HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Hematology / Hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.226 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Hematology / Hemoglobin HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.271 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell number HOM 10f:10m 0.406 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Syndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Syndactylism HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Plasma cells - % of B2 cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ NKT cells - % of lymphocytes HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector gd cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total ab T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD103+ CD11b-low cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Optic Disc HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Optic Disc HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Narrow eye opening HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Narrow eye opening HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-low cDC - % of cDC HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Glycerol HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.185 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Glycerol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.921 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Heart Weight / Heart weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.127 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Heart Weight / Heart weight HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.649 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae size HOM 10f:10m Fisher Exact Test framework 0.364 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pre-B cells (Hardy fraction D) - % of B220+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD4+ NKT cells - % of CD4+ NKT cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin appearance HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae colour HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ KLRG1+ alpha beta T cell number HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / IgD+ mature B cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw footpad size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw footpad size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Shape HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Shape HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Cervical processes HOM 10f:10m Fisher Exact Test framework 0.0194 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Cervical processes HOM 7f:7m Fisher Exact Test framework 0.539 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector NK cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD8+ T cells - % of ab T cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4+ NKT cells - % of CD4+ NKT cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Monocytes - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Three-point Bend / Yield Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Three-point Bend / Yield Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail count HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Cortical Thickness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Cortical Thickness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00208 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean/Body weight HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.426 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / NKT cell percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.563 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ alpha beta T cell number HOM 10f:10m 0.406 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Plasma cells - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:3m 0.211 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / Click-evoked ABR threshold HOM 5f:2m 0.351 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Synechia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Synechia HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting NK cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:3m 0.171 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 5f:2m 0.231 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Total cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.216 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Total cholesterol HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.306 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Monocyte percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Albumin HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.915 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Albumin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.986 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 6f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0164 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.638 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific IgG1 HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.739 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Transitional vertebrae HOM 7f:7m Fisher Exact Test framework 0.423 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Transitional vertebrae HOM 10f:10m Fisher Exact Test framework 0.543 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Pelvis HOM 10f:10m Fisher Exact Test framework 0.394 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Pelvis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Early germinal centre B cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Late germinal centre B cells - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna rotation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna rotation HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total ab T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Eyelid morphology HOM 10f:10m Fisher Exact Test framework 0.0268 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Eyelid morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Shape of spine HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Shape of spine HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Hematology / Mean cell volume HOM 10f:10m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_HEM_005_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Tomm20ltm1a(EUCOMM)Wtsi WTSI Hematology / Mean cell volume HOM 7f:7m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_HEM_005_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction C) - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Max Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Max Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Femoral Microradiography / Femoral Bone Mineral Content HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Femoral Microradiography / Femoral Bone Mineral Content HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-low cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD8+ T cells - % of CD8+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD11b-high cDC - % of cDC HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / B cell CD19+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0718 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total NKT cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin colour HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Positional passivity HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Positional passivity HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail length HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair length HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Macrophages - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels HOM 9f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD4- NKT cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Number (mm-1) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Number (mm-1) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Early germinal centre B cells - % of GC cells HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD8+ T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total gd T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD4+ NKT cells - % of CD4+ NKT cells HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Mandibles HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Mandibles HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna touch reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna touch reflex HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair presence HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Ly6C+ immature NK cells - % of immature NK cells HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector Treg cells - % of Treg HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Mouth morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Mouth morphology HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Granulocytes - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Effector CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Number of digits HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Number of digits HOM 7f:7m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 3f:0m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA score HOM 0f:3m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Total T cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Resting NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ CD8+ T cells - % of CD8+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Ly6Chigh monocyte percentage HOM 10f:10m 0.0958 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI DSS Histology / Average histology score HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair presence HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Plasma cells - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Vertebral Microradiography / Vertebral Bone Mineral Content HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Vertebral Microradiography / Vertebral Bone Mineral Content HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Fructosamine HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0759 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Fructosamine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.817 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 3f:0m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Anti-nuclear antibody assay / ANA classification HOM 0f:3m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Alkaline phosphatase HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00541 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Alkaline phosphatase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.799 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Eye Hemorrhage or Blood Presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Eye Hemorrhage or Blood Presence HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Teeth HOM 10f:10m Fisher Exact Test framework 0.303 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Teeth HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair length HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Immature NK cells - % of NK cells HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Internal Diameter HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Internal Diameter HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD4+ alpha beta T cell number HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD4+ T helper cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / CD4+CD44+CD62L- percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0786 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific IgG2 HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.194 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / DETC coverage HOM 3f:3m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Fusion between cornea and lens HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Fusion between cornea and lens HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Hematology / Mean corpuscular hemoglobin HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00807 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Hematology / Mean corpuscular hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.319 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total CD4+ T cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair presence HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw size HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ NK cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.122 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.554 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Total bilirubin HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0330 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Clinical Chemistry / Total bilirubin HOM 10f:9m Mixed Model framework, linear mixed-effects model, equation withWeight 0.339 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Fusion of ribs HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Fusion of ribs HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Conventional DC (cDC) - % of DC HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb grasping HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb grasping HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / T cells - % of CD45+ HOM 1f:1m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / BMC/Body weight HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.121 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.734 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / KLRG1+ gd T cells - % of gd T cells HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair appearance HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail count HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Neutrophil number HOM 10f:10m 0.0935 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Stiffness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Stiffness HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Structure HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Structure HOM 9f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Germinal centre B cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / CD11b-high cDC - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / CD8+ CD44+ CD62L- alpha beta effector T cell number HOM 10f:10m 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Joints HOM 7f:7m Fisher Exact Test framework 0.114 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Joints HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Resting CD8+ T cells - % of CD8+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / KLRG1+ Treg cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin appearance HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI X-ray / Fusion of processes HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI X-ray / Fusion of processes HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Hematology / Red blood cell distribution width HOM 10f:10m Mixed Model framework, linear mixed-effects model, equation withWeight 0.241 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Hematology / Red blood cell distribution width HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.540 Success
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout size HOM 10f:10m Fisher Exact Test framework 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total CD4+ NKT cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Whole blood peripheral blood leukocyte immunophenotyping / Alpha beta T cell percentage HOM 10f:10m 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Ear epidermis immunophenotyping / Average no of branches on LC HOM 3f:3m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / CD5+ gd T cells - % of CD45+ HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Effector CD4- NKT cells - % of CD45+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Bone marrow immunophenotyping / Pro-B cells (Hardy fraction B) - % of B220+ HOM 0f:0m Manual Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Three-point Bend / Max Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Three-point Bend / Max Load HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1b(EUCOMM)Wtsi WTSI Mesenteric Lymph Node Immunophenotyping / Total T cells - % of CD45+ HOM 4f:4m Manual 1.00 Success
Tomm20ltm1b(EUCOMM)Wtsi WTSI Spleen Immunophenotyping / Total Treg cells - % of CD4+ HOM 2f:2m Manual 1.00 Not processed - Data analysis pending
Tomm20ltm1b(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair length HOM 10f:10m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Tomm20ltm1b(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Bone Volume/Tissue Volume (%) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data
Tomm20ltm1a(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Bone Volume/Tissue Volume (%) HOM 2f:0m Not processed 1.00 FAILED - Not enough mutant or control data

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584) N/A
Aorta 4 No N/A
Blood vessel 4 No N/A
Bone 4 No N/A
Brain 4 No N/A
Brainstem 4 No N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No N/A
Cerebellum 4 No N/A
Cerebral cortex 4 No N/A
Eye 4 No N/A
Gall bladder 4 No N/A
Heart 4 No N/A
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Kidney 4 No  (18/584) N/A
Large intestine 4 No  (10/584) N/A
Liver 4 No N/A
Lower urinary tract 4 No N/A
Lung 4 No N/A
Lymph node 4 No N/A
Mammary gland 4 No N/A
Esophagus 4 No N/A
Olfactory lobe 4 No N/A
Ovary 4 No  (1/584) N/A
Oviduct 4 No N/A
Pancreas 4 No  (5/584) N/A
Parathyroid gland 4 No N/A
Peripheral nervous system 4 No N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No N/A
Prostate gland 4 No  (12/584) N/A
Skeletal muscle tissue 4 No N/A
Skin 4 No N/A
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No N/A
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584) N/A
Striatum 4 No N/A
Testis 4 No  (2/584)