Gene: Mindy1

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Name
MINDY lysine 48 deubiquitinase 1
MGI ID
MGI:1922257
Synonyms
cI-40 4930504E06Rik 1810005H09Rik Fam63a NF-E2 inducible protein
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating glycerol level Fam63atm1a(EUCOMM)Wtsi HOM Early adult 1.88×10-07
abnormal locomotor activation Mindy1tm1a(EUCOMM)Wtsi HOM Early adult 8.25×10-10
increased circulating alkaline phosphatase level Fam63atm1a(EUCOMM)Wtsi HOM Early adult 4.93×10-05
increased bone mineral content Mindy1tm1b(EUCOMM)Wtsi HOM Early adult 7.30×10-05
abnormal spine curvature Mindy1tm1b(EUCOMM)Wtsi HOM Early adult 2.40×10-07
decreased circulating free fatty acid level Fam63atm1a(EUCOMM)Wtsi HOM Early adult 1.92×10-08
decreased total body fat amount Mindy1tm1b(EUCOMM)Wtsi HOM Early adult 2.72×10-06
hyperactivity Mindy1tm1b(EUCOMM)Wtsi HOM Early adult 9.51×10-07
decreased body weight Fam63atm1a(EUCOMM)Wtsi HOM Early adult 1.35×10-05
increased hemoglobin content Mindy1tm1a(EUCOMM)Wtsi HOM Early adult 3.27×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (4/4)  Wholemount images
Aorta 4 No  (2/4) N/A
Blood vessel 2 No  (2/2) N/A
Bone 4 No  (4/4)  Wholemount images
Brain 4 No  (4/4)  Wholemount images
Brainstem 4 No  (2/4)  Wholemount images
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (4/4)  Wholemount images
Cerebellum 4 No  (2/4)  Wholemount images
Cerebral cortex 4 No  (2/4)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 4 No  (4/4)  Wholemount images
Gall bladder 4 No  (4/4) N/A
Heart 4 No  (4/4)  Wholemount images
Hippocampus 4 No  (2/4)  Wholemount images
Hypothalamus 4 No  (2/4)  Wholemount images
Kidney 4 No  (18/584)  (4/4)  Wholemount images
Large intestine 4 No  (10/584)  (2/4)  Wholemount images
Liver 4 No  (4/4)  Wholemount images
Lower urinary tract 4 No  (2/4)  Wholemount images
Lung 4 No  (4/4)  Wholemount images
Lymph node 4 No  (4/4) N/A
Mammary gland 4 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 4 No  (2/4)  Wholemount images
Oral epithelium 2 No N/A
Ovary 4 No  (1/584)  (2/4)  Wholemount images
Oviduct 4 No  (2/4)  Wholemount images
Pancreas 4 No  (5/584)  (4/4)  Wholemount images
Parathyroid gland 4 No  (4/4)  Wholemount images
Peripheral nervous system 4 No  (4/4)  Wholemount images
Peyer's patch 2 No N/A
Peyer's patch 2 No  (1/2)  Wholemount images
Pituitary gland 4 No  (4/4)  Wholemount images
Prostate gland 4 No  (12/584)  (1/4)  Wholemount images
Skeletal muscle 2 No  (2/2)  Wholemount images
Skeletal muscle tissue 2 No  (2/2) N/A
Skin 4 No  (4/4)  Wholemount images
Small intestine 4 No  (9/584)  (2/4)  Wholemount images
Spinal cord 4 No  (4/4)  Wholemount images
Spleen 4 No  (2/584)  (1/4) N/A
Stomach 4 No  (12/584)  (4/4)  Wholemount images
Striatum 4 No  (2/4)  Wholemount images
Testis 4 No  (2/584)  (2/4)  Wholemount images
Thymus 4 No  (2/4)  Wholemount images
Thyroid gland 4 No  (15/584)  (3/4)  Wholemount images
Trachea 4 No  (4/4)  Wholemount images
Uterus 4 No  (2/4) N/A
Vascular system 2 No N/A
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (3/4) N/A
Ear 2  (1/504)  (1/4) N/A
Embryo 2  (1/505)  (4/4) N/A
Eye 2  (1/504)  (3/4) N/A
Foot 2  (1/504)  (1/4) N/A
Forebrain 2  (1/504)  (3/4) N/A
Forelimb 2  (1/504)  (4/4) N/A
Hand 2  (1/503)  (1/4) N/A
Head 2  (5/504)  (4/4) N/A
Heart 2  (1/504)  (2/4) N/A
Hindbrain 2  (6/504)  (3/4) N/A
Hindlimb 2  (1/503)  (4/4) N/A
Liver 2  (1/504)  (1/4) N/A
Lung 2  (1/500)  (1/4) N/A
Mandibular process 2  (1/504)  (1/4) N/A
Maxillary process 2  (1/504)  (1/4) N/A
Midbrain 2  (1/504)  (3/4) N/A
Oral cavity 2  (1/504)  (2/4) N/A
Skin 2  (1/504)  (1/4) N/A
Tail 2  (1/504)  (4/4) N/A
Tail somite 2  (1/504)  (2/4) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
Adult LacZ: LacZ Images Wholemount
24 Images
Echo: M-Mode Images
32 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Mindy1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Mindy1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Mindy1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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