Mindy1 | MINDY lysine 48 deubiquitinase 1

GeneMGI:1922257Synonyms: NF-E2 inducible protein, 1810005H09Rik, +3 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

18 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

decreased circulating free fatty acids level1 supporting datasetMindy1tm1a(EUCOMM)WtsihomozygoteEarly adult6.04x10-9 
decreased circulating amylase level1 supporting datasetMindy1tm1a(EUCOMM)WtsihomozygoteEarly adult7.3x10-5 
abnormal locomotor activation1 supporting datasetMindy1tm1a(EUCOMM)WtsihomozygoteEarly adult1.58x10-9 
decreased circulating glycerol level1 supporting datasetMindy1tm1a(EUCOMM)WtsihomozygoteEarly adult3.59x10-7 
decreased circulating calcium level1 supporting datasetMindy1tm1a(EUCOMM)WtsihomozygoteEarly adult2.6x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mindy1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Mindy1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Mindy1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Mindy1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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