Usp38 | ubiquitin specific peptidase 38
Physiological systems
20 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Skeleton
12 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
decreased lean body mass | 2 supporting datasets | Usp38tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.95x10-15 | ||
decreased prepulse inhibition | 3 supporting datasets | Usp38tm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.97x10-6 | ||
persistence of hyaloid vascular system | 1 supporting dataset | Usp38tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2x10-5 | ||
increased total body fat amount | 2 supporting datasets | Usp38tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.26x10-14 | ||
thrombocytopenia | 1 supporting dataset | Usp38tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.33x10-7 | ||
decreased exploration in new environment | 1 supporting dataset | Usp38tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2x10-5 | ||
abnormal bone structure | 1 supporting dataset | Usp38tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.55x10-7 | ||
increased mean corpuscular volume | 1 supporting dataset | Usp38tm1b(EUCOMM)Hmgu | homozygote | Early adult | 6.26x10-5 | ||
decreased circulating creatinine level | 1 supporting dataset | Usp38tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.74x10-5 |
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External links
No external links available for Usp38.
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Usp38tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Usp38tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Usp38tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |