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Gene: Pik3cb

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Name
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
MGI ID
MGI:1922019
Synonyms
1110001J02Rik p110beta
Viability
No data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (174) All data table (568)
Expression & images (45) Disease models (0) Histopathology (1) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased mean corpuscular hemoglobin Pik3cbtm1a(EUCOMM)Wtsi HOM   Early adult 3.75×10-06
increased hemoglobin content Pik3cbtm1a(EUCOMM)Wtsi HOM   Early adult 7.66×10-06
increased mean corpuscular hemoglobin Pik3cbtm1a(EUCOMM)Wtsi HET Early adult 6.53×10-10
decreased circulating creatinine level Pik3cbtm1a(EUCOMM)Wtsi HET Early adult 3.13×10-05
increased hemoglobin content Pik3cbtm1a(EUCOMM)Wtsi HET Early adult 1.05×10-08

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Blood vessel 2 No N/A
Bone 2 No  (2/2) N/A
Brain 2 No  (4/583)  (2/2) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583)  (1/2) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (1/2) N/A
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583)  (2/2) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563)  (1/2) N/A
Peripheral nervous system 2 No  (2/583)  (2/2) N/A
Peyer's patch 2 No  (1/176) N/A
Pituitary gland 2 No  (1/583)  (1/2) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No  (1/583)  (1/2) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583)  (2/2) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583)  (1/2) N/A
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2) N/A
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Pik3cbtm1a(EUCOMM)Wtsi
brain, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
bone, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
skin, HET, Male, WTSI

View all 14 images

Pik3cbtm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
heart, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
stomach, oesophagus, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
ovary, oviduct, HET, Female, WTSI

View all 8 images

Pik3cbtm1a(EUCOMM)Wtsi
brain, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
brain, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
pituitary gland, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
spinal cord, HET, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
ovary, oviduct, HET, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
heart, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
stomach, oesophagus, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
thyroid gland, HET, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
spleen, HET, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
skin, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
bone, HET, Male, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

thumbnail
Histopathology
6 Images
Legacy Phenotype Associated Images
Pik3cbtm1a(EUCOMM)Wtsi
body, HET, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
HET, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
body, HOM, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
head, HOM, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
head, HOM, Female, WTSI

View all 180 images

Pik3cbtm1a(EUCOMM)Wtsi
eye, cornea/lens fusion, corneal opacity, HOM, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
eye, cornea/lens fusion, corneal opacity, HOM, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
eye, corneal opacity, HOM, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
back skin, HOM, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
back skin, HOM, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
tail skin, WT, Female, WTSI
Pik3cbtm1a(EUCOMM)Wtsi
tail skin, WT, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Testes - hypoplasia Pik3cbtm1a(EUCOMM)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pik3cbtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Pik3cbtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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