Gene: Trim14

Name
tripartite motif-containing 14
MGI ID
MGI:1921985
Synonyms
5830400N10Rik
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (55) Expression & images (0) Disease models (0) Order (2)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Alanine aminotransferase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.645 Success
Trim14em1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.494 Success
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Creatinine HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0752 Success
Trim14em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.640 Success
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Alkaline phosphatase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.428 Success
Trim14em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 0.307 Success
Trim14em1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.607 Success
Trim14em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Total cholesterol HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.862 Success
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Total protein HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.907 Success
Trim14em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.647 Success
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Albumin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.981 Success
Trim14em1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.467 Success
Trim14em1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.651 Success
Trim14em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Bone Area HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.888 Success
Trim14em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Trim14em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Body length HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.481 Success
Trim14em1(IMPC)Mbp UC Davis Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.518 Success
Trim14em1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.833 Success
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Total bilirubin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.952 Success
Trim14em1(IMPC)Mbp UC Davis Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Aspartate aminotransferase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.649 Success
Trim14em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0404 Success
Trim14em1(IMPC)Mbp UC Davis Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.998 Success
Trim14em1(IMPC)Mbp UC Davis Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trim14em1(IMPC)Mbp UC Davis Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Trim14em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Trim14em1(IMPC)Mbp UC Davis Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Calcium HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.407 Success
Trim14em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.628 Success
Trim14em1(IMPC)Mbp UC Davis Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.742 Success
Trim14em1(IMPC)Mbp UC Davis Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Glucose HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.116 Success
Trim14em1(IMPC)Mbp UC Davis Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trim14em1(IMPC)Mbp UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Trim14em1(IMPC)Mbp UC Davis Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.751 Success
Trim14em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.334 Success
Trim14em1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.514 Success
Trim14em1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.666 Success
Trim14em1(IMPC)Mbp UC Davis Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trim14em1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0841 Success
Trim14em1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.530 Success
Trim14em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Fat mass HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.546 Success
Trim14em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Phosphorus HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.241 Success
Trim14em1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.374 Success
Trim14em1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.919 Success
Trim14em1(IMPC)Mbp UC Davis Viability Primary Screen / Outcome HOM 45f:42m Supplied as data Success
Trim14em1(IMPC)Mbp UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Trim14em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Lean mass HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.134 Success
Trim14em1(IMPC)Mbp UC Davis Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Trim14em1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.860 Success
Trim14em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Triglycerides HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.559 Success
Trim14em1(IMPC)Mbp UC Davis Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0102 Success

 Expression

Expression data not available

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Trim14em1(IMPC)Mbp Inter-exdel deletion Mice, Tissue
Trim14tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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