The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
|enhanced cued conditioning behavior
|embryonic lethality prior to tooth bud stage
|abnormal auditory brainstem response
|preweaning lethality, complete penetrance
Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Tasor by phenotypic similarity.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Tasor.
There are 2 publications which use IMPC produced mice or data.
|Dual role of Fam208a during zygotic cleavage and early embryonic development.
|Experimental cell research (July 2021)
|Fam208a orchestrates interaction protein network essential for early embryonic development and cell division.
|Experimental cell research (May 2019)