Rptor | regulatory associated protein of MTOR, complex 1
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Mortality/aging Cardiovascular system
17 No significant impact
5 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Rptortm2b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
abnormal sinus arrhythmia | 1 supporting dataset | Rptortm2b(EUCOMM)Wtsi | heterozygote | Early adult | 5.08x10-5 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Rptortm2b(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Rptor.
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Rptortm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
Rptortm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Rptortm2b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Rptortm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |