Rptor | regulatory associated protein of MTOR, complex 1

GeneMGI:1921620Synonyms: raptor, Rap, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Mortality/aging Cardiovascular system

17 No significant impact

5 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues

Phenotypes

embryonic lethality prior to tooth bud stage1 supporting datasetRptortm2b(EUCOMM)WtsihomozygoteE12.5N/A * 
abnormal sinus arrhythmia1 supporting datasetRptortm2b(EUCOMM)WtsiheterozygoteEarly adult5.08x10-5 
preweaning lethality, complete penetrance1 supporting datasetRptortm2b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rptortm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Rptortm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Rptortm2b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Rptortm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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