Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
golgi associated, gamma adaptin ear containing, ARF binding protein 2
Synonyms:
1200007E24Rik

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Gga2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Gga2 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Granulomas, Congenital Cerebral
Neonatal death OMIM:306300
Genitourinary Tract Anomalies
Neonatal death OMIM:305690
3-Hydroxy-3-Methylglutaryl-Coa Synthase Deficiency
Hypoglycemia ORPHA:35701
Hyperinsulinemic Hypoglycemia, Familial, 7
Hypoglycemic seizures, Hypoglycemia, Hyperinsulinemia, Hyperinsulinemic hypoglycemia OMIM:610021
Hypoinsulinemic Hypoglycemia And Body Hemihypertrophy
Nonketotic hypoglycemia, Hypoglycemic seizures, Neonatal hypoglycemia, Hypoketotic hypoglycemia ORPHA:293964
Glycogen Storage Disease 0, Liver
Neonatal hypoglycemia, Postprandial hyperglycemia, Fasting hypoglycemia OMIM:240600
Hyperinsulinism Due To Insr Deficiency
Hyperinsulinemic hypoglycemia, Hypoglycemia, Recurrent hypoglycemia, Insulin resistance, Fasting ... ORPHA:263458
Dwarfism, Low-Birth-Weight Type, With Unresponsiveness To Growth Hormone
Hypoglycemia OMIM:223500
Fructose And Galactose Intolerance
Hypoglycemia OMIM:229500
Short Stature Due To Partial Ghr Deficiency
Hypoglycemia ORPHA:314802
Congenital Glucokinase-Related Hyperinsulinism
Hypoketotic hypoglycemia, Type II diabetes mellitus, Recurrent hypoglycemia, Hyperinsulinemic hyp... ORPHA:79299
Hyperinsulinemic Hypoglycemia, Familial, 2
Hyperinsulinemic hypoglycemia, Hypoglycemia OMIM:601820
Insulin Autoimmune Syndrome
Hyperinsulinemic hypoglycemia, Fasting hypoglycemia, Nonketotic hypoglycemia, Insulin resistance,... ORPHA:411593
Hypoinsulinemic Hypoglycemia With Hemihypertrophy
Neonatal hypoglycemia, Hypoinsulinemia, Hypoglycemia, Fasting hypoglycemia OMIM:240900
Phosphoenolpyruvate Carboxykinase Deficiency, Mitochondrial
Hypoglycemia, Impaired gluconeogenesis OMIM:261650
Long-Chain 3-Hydroxyacyl-Coa Dehydrogenase Deficiency
Hypoglycemia OMIM:609016
Glycogen Storage Disease Due To Glycogen Debranching Enzyme Deficiency
Hypoglycemia ORPHA:366
Hypoglycemia, Leucine-Induced
Hyperinsulinemic hypoglycemia, Hypoglycemia OMIM:240800
Short Stature Due To Ghsr Deficiency
Hypoglycemia ORPHA:314811
Pulmonary Hypoplasia, Primary
Neonatal death OMIM:265430
Pituitary Hormone Deficiency, Combined, 4
Hypoglycemia OMIM:262700
Isolated Growth Hormone Deficiency, Type Ia
Hypoglycemia OMIM:262400
Epidermolysis Bullosa With Diaphragmatic Hernia
Neonatal death OMIM:226735
Maturity-Onset Diabetes Of The Young, Type 3
Maturity-onset diabetes of the young, Hyperglycemia, Type II diabetes mellitus OMIM:600496
Hyperinsulinism Due To Hnf1A Deficiency
Hypoglycemic seizures, Neonatal hypoglycemia, Hyperinsulinemia, Maturity-onset diabetes of the yo... ORPHA:324575
Diaphragmatic Hernia 5, X-Linked
Neonatal death OMIM:306950
3-Methylglutaconic Aciduria Type 1
Hypoglycemia ORPHA:67046
Mitochondrial Complex Iii Deficiency, Nuclear Type 3
Hypoglycemia OMIM:615158
Homozygous 11P15-P14 Deletion Syndrome
Hypoglycemia, Hyperinsulinemia OMIM:606528
Glycogen Storage Disease Vi
Hypoglycemia OMIM:232700
Hyperinsulinism-Hyperammonemia Syndrome
Hyperinsulinemic hypoglycemia, Fasting hyperinsulinemia, Reactive hypoglycemia ORPHA:35878
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome
Hyperinsulinemia, Fasting hypoglycemia, Hypoketotic hypoglycemia, Hyperinsulinemic hypoglycemia, ... ORPHA:276608
Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities
Hyperinsulinemia, Fasting hypoglycemia, Hyperglycemia, Diabetic ketoacidosis, Hypoglycemia, Postp... OMIM:262190
Neonatal Hemochromatosis
Hypoglycemia ORPHA:446
Short Stature-Delayed Bone Age Due To Thyroid Hormone Metabolism Deficiency
Fasting hypoglycemia ORPHA:171706
Pyridoxamine 5-Prime-Phosphate Oxidase Deficiency
Hypoglycemia OMIM:610090
Autosomal Dominant Hyperinsulinism Due To Kir6.2 Deficiency
Hypoglycemic seizures, Hyperinsulinemia, Maternal diabetes, Hypoketotic hypoglycemia, Fasting hyp... ORPHA:276580
Neutropenia, Lethal Congenital, With Eosinophilia
Neonatal death OMIM:257100
Hyperinsulinemic Hypoglycemia, Familial, 8
Hypoglycemic seizures, Hypoglycemia, Hyperinsulinemia OMIM:620211
Dicarboxylic Aminoaciduria
Fasting hypoglycemia OMIM:222730
Endocardial Fibroelastosis
Hypoglycemia ORPHA:2022
Dihydrolipoamide Dehydrogenase Deficiency
Hypoglycemia, Death in childhood OMIM:246900
Hyperinsulinism Due To Ucp2 Deficiency
Hypoglycemic seizures, Hypoketotic hypoglycemia, Recurrent hypoglycemia, Hyperinsulinemic hypogly... ORPHA:276556
Combined Oxidative Phosphorylation Deficiency 40
Hypoglycemia, Neonatal death, Death in infancy OMIM:618835
Combined Oxidative Phosphorylation Deficiency 42
Hypoglycemia, Neonatal death, Death in infancy OMIM:618839
Mitochondrial Complex Iii Deficiency, Nuclear Type 9
Hypoglycemia OMIM:616111
Autosomal Dominant Hyperinsulinism Due To Sur1 Deficiency
Hypoglycemic seizures, Hyperinsulinemia, Hypoketotic hypoglycemia, Fasting hypoglycemia, Hyperins... ORPHA:276575
Orthostatic Hypotension 2
Hypoglycemia OMIM:618182
Diarrhea 13
Recurrent hypoglycemia OMIM:620357
Mitochondrial Dna Depletion Syndrome 9 (Encephalomyopathic Type With Methylmalonic Aciduria)
Hypoglycemia, Neonatal death, Death in childhood, Death in infancy OMIM:245400
3-Methylcrotonyl-Coa Carboxylase Deficiency
Hypoglycemia ORPHA:6
Propionic Acidemia
Hypoglycemia ORPHA:35
Silver-Russell Syndrome Due To An Imprinting Defect Of 11P15
Neonatal hypoglycemia, Hypoglycemia ORPHA:231140
Intellectual Developmental Disorder With Macrocephaly, Seizures, And Speech Delay
Recurrent hypoglycemia OMIM:618158
Silver-Russell Syndrome Due To Maternal Uniparental Disomy Of Chromosome 11
Hypoglycemia ORPHA:231147
Isobutyryl-Coa Dehydrogenase Deficiency
Ketotic hypoglycemia ORPHA:79159
Mehmo Syndrome
Hypoglycemia OMIM:300148
Mitochondrial Pyruvate Carrier Deficiency
Hypoglycemia OMIM:614741
3-Methylglutaconic Aciduria Type 4
Hypoglycemia ORPHA:67048
Riboflavin Deficiency
Hypoglycemia OMIM:615026
Monocarboxylate Transporter 1 Deficiency
Ketotic hypoglycemia OMIM:616095
Ornithine Transcarbamylase Deficiency
Hypoglycemia ORPHA:664
Combined Oxidative Phosphorylation Deficiency 52
Hypoglycemia, Death in infancy OMIM:619386
2-Methylbutyryl-Coa Dehydrogenase Deficiency
Hypoglycemia OMIM:610006
Short Chain Acyl-Coa Dehydrogenase Deficiency
Ketotic hypoglycemia ORPHA:26792
Hsd10 Mitochondrial Disease
Hypoglycemia OMIM:300438
Mitochondrial Complex Iv Deficiency, Nuclear Type 4
Hypoglycemia OMIM:619048
Glycogen Storage Disease Iii
Hypoglycemia OMIM:232400
Mitochondrial Complex I Deficiency, Nuclear Type 19
Hypoglycemia OMIM:618241
Mitochondrial Complex Iii Deficiency, Nuclear Type 11
Hypoglycemia OMIM:620137
Mitochondrial Trifunctional Protein Deficiency 2
Hypoglycemia, Neonatal death, Death in infancy OMIM:620300
Combined Oxidative Phosphorylation Deficiency 34
Hypoglycemia OMIM:617872
2P21 Microdeletion Syndrome
Hypoglycemia ORPHA:163693
Combined Malonic And Methylmalonic Acidemia
Hypoglycemia ORPHA:289504
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency
Hypoglycemia ORPHA:364
Pyridoxine-Dependent Epilepsy
Hypoglycemia ORPHA:3006
Congenital Cataracts-Facial Dysmorphism-Neuropathy Syndrome
Hypoglycemia ORPHA:48431
Insulinoma
Hyperinsulinemia, Nonketotic hypoglycemia, Recurrent hypoglycemia, Hyperinsulinemic hypoglycemia,... ORPHA:97279
Mitochondrial Complex Iv Deficiency, Nuclear Type 12
Neonatal hypoglycemia, Death in childhood, Death in adolescence, Death in infancy, Neonatal death... OMIM:619055
Combined Oxidative Phosphorylation Deficiency 47
Hypoglycemia OMIM:618958
Glycogen Storage Disease Due To Hepatic Glycogen Synthase Deficiency
Glycosuria, Ketotic hypoglycemia, Postprandial hyperglycemia ORPHA:2089
Combined Oxidative Phosphorylation Deficiency 36
Hypoglycemia OMIM:617950
Glycogen Storage Disease Ixb
Hypoglycemia OMIM:261750
Mody
Neonatal hypoglycemia, Hypoinsulinemia, Glycosuria, Hyperglycemia, Transient neonatal diabetes me... ORPHA:552
Hemochromatosis, Neonatal
Hypoglycemia OMIM:231100
Mitochondrial Complex Iii Deficiency, Nuclear Type 5
Hypoglycemia OMIM:615160
Mitochondrial Complex V (Atp Synthase) Deficiency, Nuclear Type 5
Hypoglycemia OMIM:618120
Glycogen Storage Disease Due To Liver Glycogen Phosphorylase Deficiency
Hypoglycemia ORPHA:369
Pyruvate Carboxylase Deficiency
Hypoglycemia OMIM:266150
Mitochondrial Complex I Deficiency, Nuclear Type 20
Hypoglycemia, Death in childhood, Death in infancy OMIM:611126
Silver-Russell Syndrome Due To 7P11.2P13 Microduplication
Hypoglycemia ORPHA:231137
Histidinuria-Renal Tubular Defect Syndrome
Hypoglycemia ORPHA:2158
Glycogen Storage Disease Ixa1
Hypoglycemia OMIM:306000
Glucocorticoid Deficiency 3
Recurrent hypoglycemia OMIM:609197
Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic
Hypoglycemia, Fasting hypoglycemia, Impaired gluconeogenesis OMIM:261680
Congenital Hyperinsulinism Due To Hnf4A Deficiency
Neonatal hypoglycemia, Hyperinsulinemia, Hypoketotic hypoglycemia, Fasting hypoglycemia, Glycosur... ORPHA:263455
Malonyl-Coa Decarboxylase Deficiency
Hypoglycemia OMIM:248360
Silver-Russell Syndrome 2
Neonatal hypoglycemia OMIM:618905
Long Chain 3-Hydroxyacyl-Coa Dehydrogenase Deficiency
Hypoglycemia, Hypoketotic hypoglycemia ORPHA:5
Non-Acquired Isolated Growth Hormone Deficiency
Neonatal hypoglycemia ORPHA:631
Mitochondrial Complex Iv Deficiency, Nuclear Type 3
Neonatal hypoglycemia, Death in infancy OMIM:619046
Glycogen Storage Disease Ixc
Hypoglycemia, Fasting hypoglycemia OMIM:613027
Hypoadrenocorticism, Familial
Hypoglycemia OMIM:240200
Adrenal Hyperplasia, Congenital, Due To 21-Hydroxylase Deficiency
Hypoglycemia OMIM:201910
3-Methylglutaconic Aciduria With Deafness, Encephalopathy, And Leigh-Like Syndrome
Hypoglycemia OMIM:614739
Pyruvate Dehydrogenase E3 Deficiency
Hypoglycemia ORPHA:2394
Combined Oxidative Phosphorylation Deficiency 10
Hypoglycemia OMIM:614702
Temple Syndrome
Type II diabetes mellitus, Recurrent hypoglycemia ORPHA:254516
Glycogen Storage Disease Ixd
Hypoglycemia OMIM:300559
Infantile Liver Failure Syndrome 2
Hypoglycemia OMIM:616483
Blue Diaper Syndrome
Increased proinsulin:insulin ratio, Recurrent hypoglycemia ORPHA:94086
Multiple Acyl-Coa Dehydrogenase Deficiency
Glycosuria, Hypoglycemia, Neonatal death OMIM:231680
Autosomal Recessive Hyperinsulinism Due To Kir6.2 Deficiency
Hyperinsulinemic hypoglycemia, Neonatal hypoglycemia, Recurrent hypoglycemia ORPHA:79644
Laron Syndrome
Hypoglycemia ORPHA:633
Congenital Isolated Acth Deficiency
Hypoglycemic seizures, Neonatal hypoglycemia ORPHA:199296
Long-Olsen-Distelmaier Syndrome
Hypoglycemia, Death in childhood OMIM:620609
Combined Oxidative Phosphorylation Deficiency 41
Hypoglycemia OMIM:618838
Cholestasis, Progressive Familial Intrahepatic, 5
Hypoglycemia, Death in infancy OMIM:617049
Proprotein Convertase 1/3 Deficiency
Hypoinsulinemia, Reactive hypoglycemia OMIM:600955
Aromatic L-Amino Acid Decarboxylase Deficiency
Hypoglycemia ORPHA:35708
Pyridoxal Phosphate-Responsive Seizures
Hypoglycemia ORPHA:79096
Primary Microcephaly-Mild Intellectual Disability-Young-Onset Diabetes Syndrome
Hypoglycemia, Diabetes mellitus ORPHA:391408
Polyendocrine-Polyneuropathy Syndrome
Hypoglycemia, Hypoinsulinemia, Type II diabetes mellitus ORPHA:453533
Acth Deficiency, Isolated
Fasting hypoglycemia OMIM:201400
Pituitary Stalk Interruption Syndrome
Hypoglycemia, Death in infancy ORPHA:95496
Mitochondrial Complex Iv Deficiency, Nuclear Type 23
Hypoglycemia, Death in infancy OMIM:620275
Classic Galactosemia
Hypoglycemia ORPHA:79239
Medium Chain Acyl-Coa Dehydrogenase Deficiency
Hypoglycemia ORPHA:42
Mitochondrial Complex I Deficiency, Nuclear Type 33
Hypoglycemia OMIM:618253
Carnitine Palmitoyl Transferase 1A Deficiency
Hypoglycemia ORPHA:156
Glucocorticoid Resistance, Generalized
Hypoglycemia OMIM:615962
Galactokinase Deficiency
Hypoglycemia, Hyperinsulinemia ORPHA:79237
Glucocorticoid Deficiency 2
Hypoglycemia, Recurrent hypoglycemia OMIM:607398
Neurodevelopmental Disorder, Mitochondrial, With Abnormal Movements And Lactic Acidosis, With Or Without Seizures
Hypoglycemia OMIM:617710
Cataract-Growth Hormone Deficiency-Sensory Neuropathy-Sensorineural Hearing Loss-Skeletal Dysplasia Syndrome
Fasting hypoglycemia ORPHA:436174
Houge-Janssens Syndrome 1
Hypoglycemia OMIM:616355
Growth Delay Due To Insulin-Like Growth Factor Type 1 Deficiency
Insulin resistance, Hypoglycemia ORPHA:73272
3-Hydroxyacyl-Coa Dehydrogenase Deficiency
Hypoglycemic seizures, Hypoketotic hypoglycemia OMIM:231530
Fanconi Renotubular Syndrome 4 With Maturity-Onset Diabetes Of The Young
Glycosuria, Hypoglycemia, Diabetes mellitus OMIM:616026
Hsd10 Disease, Infantile Type
Hypoglycemia ORPHA:391428
Carnitine Palmitoyltransferase Ii Deficiency, Infantile
Hypoketotic hypoglycemia OMIM:600649
Mitochondrial Complex Iii Deficiency, Nuclear Type 6
Hypoglycemia, Hyperglycemia OMIM:615453
Pituitary Hormone Deficiency, Combined, 2
Hypoglycemic seizures, Neonatal hypoglycemia OMIM:262600
Post-Traumatic Pituitary Deficiency
Hypoglycemia ORPHA:95619
Fructose-1,6-Bisphosphatase Deficiency
Neonatal hypoglycemia, Hypoglycemia, Fasting hypoglycemia ORPHA:348
Solitary Fibrous Tumor
Hypoglycemia, Hypoinsulinemia, Recurrent hypoglycemia ORPHA:2126
Pituitary Hormone Deficiency, Combined, 6
Neonatal hypoglycemia, Hypoglycemia OMIM:613986
Aica-Ribosiduria Due To Atic Deficiency
Hypoglycemia OMIM:608688
Carnitine Deficiency, Systemic Primary
Recurrent hypoglycemia, Impaired gluconeogenesis OMIM:212140
Insulin-Resistance Syndrome Type B
Hyperinsulinemia, Hyperinsulinemic hypoglycemia, Fasting hypoglycemia, Glycosuria, Hyperglycemia,... ORPHA:2298
Propionic Acidemia
Hypoglycemia OMIM:606054
Donohue Syndrome
Hyperinsulinemia, Hyperglycemia, Postprandial hyperglycemia, Fasting hypoglycemia OMIM:246200
Cog8-Cdg
Hypoglycemia ORPHA:95428
Smith-Kingsmore Syndrome
Hypoglycemia OMIM:616638
Carnitine-Acylcarnitine Translocase Deficiency
Neonatal hypoglycemia, Hypoglycemia OMIM:212138
Timothy Syndrome
Hypoglycemia OMIM:601005
Acyl-Coa Dehydrogenase, Medium-Chain, Deficiency Of
Hypoglycemia OMIM:201450
Microcephaly, Short Stature, And Impaired Glucose Metabolism 2
Recurrent hypoglycemia OMIM:616817
Maple Syrup Urine Disease, Type Ia
Hypoglycemia OMIM:248600
Glucocorticoid Deficiency 4 With Or Without Mineralocorticoid Deficiency
Hypoglycemia OMIM:614736
Polyendocrine-Polyneuropathy Syndrome
Type I diabetes mellitus, Hypoglycemia OMIM:616113
Bachmann-Bupp Syndrome
Hypoglycemia OMIM:619075
Hypotonia-Cystinuria Syndrome
Neonatal hypoglycemia OMIM:606407
Mitochondrial Complex Iv Deficiency, Nuclear Type 22
Hypoglycemia, Death in infancy OMIM:619355
Hyperinsulinism Due To Short Chain 3-Hydroxylacyl-Coa Dehydrogenase Deficiency
Hypoglycemic seizures, Neonatal hypoglycemia, Hypoketotic hypoglycemia, Hyperinsulinemic hypoglyc... ORPHA:71212
Fanconi-Bickel Syndrome
Fasting hypoglycemia, Impaired glucose tolerance, Glycosuria, Diabetes mellitus, Postprandial hyp... ORPHA:2088
3-Methylcrotonyl-Coa Carboxylase 1 Deficiency
Hypoglycemia OMIM:210200
Acyl-Coa Dehydrogenase, Very Long-Chain, Deficiency Of
Nonketotic hypoglycemia, Death in infancy OMIM:201475
Immunodeficiency, Common Variable, 10
Hypoglycemia OMIM:615577
Carnitine Palmitoyltransferase Ii Deficiency, Lethal Neonatal
Nonketotic hypoglycemia, Hypoglycemia, Death in infancy OMIM:608836
Basilicata-Akhtar Syndrome
Neonatal hypoglycemia OMIM:301032
Glucocorticoid Deficiency 1
Recurrent hypoglycemia OMIM:202200
Shashi-Pena Syndrome
Hypoglycemia OMIM:617190
Reni Syndrome
Hypoglycemia OMIM:617575
Silver-Russell Syndrome Due To A Point Mutation
Hypoglycemia ORPHA:397590
Pancreatic And Cerebellar Agenesis
Hypoglycemia, Diabetes mellitus, Hyperglycemia, Death in infancy OMIM:609069
Fructose-1,6-Bisphosphatase Deficiency
Hypoglycemia OMIM:229700
Silver-Russell Syndrome 1
Fasting hypoglycemia OMIM:180860
Tenorio Syndrome
Hypoglycemia, Hypoinsulinemia OMIM:616260
Methylmalonic Aciduria Due To Methylmalonyl-Coa Mutase Deficiency
Hypoglycemia OMIM:251000
3-Hydroxy-3-Methylglutaryl-Coa Synthase-2 Deficiency
Hypoglycemia OMIM:605911
Immunodeficiency 10
Hypoglycemia OMIM:612783
D-Glyceric Aciduria
Hypoglycemia OMIM:220120
Intellectual Developmental Disorder, Autosomal Dominant 45
Neonatal hypoglycemia OMIM:617600
3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency
Hypoglycemia, Death in childhood OMIM:246450
Glutaric Acidemia I
Hypoglycemia OMIM:231670
Congenital Disorder Of Glycosylation, Type Ig
Hypoglycemia OMIM:607143
Beta-Ketothiolase Deficiency
Hypoglycemia, Hyperglycemia ORPHA:134
Congenital Disorder Of Glycosylation, Type Im
Hypoketotic hypoglycemia, Death in infancy OMIM:610768
Congenital Disorder Of Glycosylation, Type Iie
Hypoglycemia, Death in infancy OMIM:608779
Multiple Acyl-Coa Dehydrogenase Deficiency
Hypoglycemia ORPHA:26791
Dopamine Beta-Hydroxylase Deficiency
Insulin resistance, Hypoglycemia, Hyperinsulinemia ORPHA:230
Cholera
Hypoglycemia, Miscarriage ORPHA:173
Recurrent Metabolic Encephalomyopathic Crises-Rhabdomyolysis-Cardiac Arrhythmia-Intellectual Disability Syndrome
Hypoglycemic seizures, Hypoglycemia ORPHA:480864
Intellectual Disability-Macrocephaly-Hypotonia-Behavioral Abnormalities Syndrome
Hypoglycemia ORPHA:457279
Glycogen Storage Disease Due To Liver Phosphorylase Kinase Deficiency
Hypoglycemia, Fasting hypoglycemia ORPHA:264580
Carnitine-Acylcarnitine Translocase Deficiency
Fasting hypoglycemia, Hypoketotic hypoglycemia ORPHA:159
Macrocephaly-Intellectual Disability-Neurodevelopmental Disorder-Small Thorax Syndrome
Neonatal hypoglycemia ORPHA:457485
Glycogen Storage Disease Due To Liver And Muscle Phosphorylase Kinase Deficiency
Ketotic hypoglycemia, Fasting hypoglycemia, Recurrent hypoglycemia ORPHA:79240
Rabson-Mendenhall Syndrome
Fasting hypoglycemia, Impaired glucose tolerance, Diabetic ketoacidosis, Insulin resistance, Fast... ORPHA:769
Combined Oxidative Phosphorylation Deficiency 59
Ketotic hypoglycemia OMIM:620646
Mirage Syndrome
Hypoglycemia OMIM:617053
Mitochondrial Complex Iii Deficiency, Nuclear Type 1
Hypoglycemia, Neonatal death, Hyperglycemia, Recurrent hypoglycemia OMIM:124000
Neurodevelopmental Disorder With Hypotonia, Dysmorphic Facies, And Skeletal Anomalies, With Or Without Seizures
Hypoglycemia OMIM:620224
Glycogen Storage Disease Ia
Hypoglycemia, Fasting hypoglycemia OMIM:232200
Midface Hypoplasia, Obesity, Developmental Delay, And Neonatal Hypotonia
Neonatal hypoglycemia OMIM:608624
Methylmalonic Aciduria, Cblb Type
Hypoglycemia OMIM:251110
Combined Oxidative Phosphorylation Defect Type 39
Neonatal hypoglycemia ORPHA:565624
Sotos Syndrome
Neonatal hypoglycemia, Glucose intolerance OMIM:117550
Combined Oxidative Phosphorylation Deficiency 58
Hypoglycemia OMIM:620451
Leigh Syndrome
Hypoglycemia ORPHA:506
Carnitine Palmitoyl Transferase Ii Deficiency, Severe Infantile Form
Hypoketotic hypoglycemia ORPHA:228305
Combined Oxidative Phosphorylation Deficiency 37
Hypoglycemia OMIM:618329
Late-Onset Isolated Acth Deficiency
Type I diabetes mellitus, Hypoglycemia ORPHA:199299
Carnitine Palmitoyltransferase I Deficiency
Hypoketotic hypoglycemia OMIM:255120
Metabolic Crises, Recurrent, With Rhabdomyolysis, Cardiac Arrhythmias, And Neurodegeneration
Hypoglycemia OMIM:616878
Cataracts, Growth Hormone Deficiency, Sensory Neuropathy, Sensorineural Hearing Loss, And Skeletal Dysplasia
Hypoglycemia OMIM:616007
Silver-Russell Syndrome
Insulin resistance, Recurrent hypoglycemia ORPHA:813
Isolated Complex I Deficiency
Hypoglycemia, Diabetes mellitus ORPHA:2609
Growth Retardation, Impaired Intellectual Development, Hypotonia, And Hepatopathy
Hypoglycemia OMIM:617093
3-Methylcrotonyl-Coa Carboxylase 2 Deficiency
Hypoglycemia OMIM:210210
Multiple Mitochondrial Dysfunctions Syndrome 7
Hypoglycemia, Hyperglycemia OMIM:620423
Congenital Disorder Of Glycosylation With Defective Fucosylation 1
Hypoglycemia OMIM:618005
3-Methylglutaconic Aciduria Type 7
Neonatal hypoglycemia ORPHA:445038
Congenital Disorder Of Glycosylation, Type Iiaa
Hypoglycemia OMIM:620454
Congenital Disorder Of Glycosylation, Type It
Hypoglycemia OMIM:614921
Cerebral Visual Impairment
Neonatal hypoglycemia ORPHA:447788
Mitochondrial Dna Depletion Syndrome 15 (Hepatocerebral Type)
Hypoglycemia, Death in infancy OMIM:617156
Mitochondrial Trifunctional Protein Deficiency 1
Hypoketotic hypoglycemia OMIM:609015
Oculodentodigital Dysplasia
Hypoglycemia ORPHA:2710
Acyl-Coa Dehydrogenase 9 Deficiency
Nonketotic hypoglycemia ORPHA:99901
Carbonic Anhydrase Va Deficiency, Hyperammonemia Due To
Hypoglycemia OMIM:615751
X-Linked Dominant Chondrodysplasia Punctata
Neonatal hypoglycemia ORPHA:35173
Mitochondrial Dna Depletion Syndrome 3 (Hepatocerebral Type)
Hypoglycemia OMIM:251880
Immunodeficiency 59 And Hypoglycemia
Hypoglycemia OMIM:233600
Fanconi-Bickel Syndrome
Glycosuria, Postprandial hyperglycemia, Fasting hypoglycemia OMIM:227810
Familial Glucocorticoid Deficiency
Ketotic hypoglycemia, Hypoglycemic seizures ORPHA:361
Pituitary Apoplexy
Hypoglycemia ORPHA:95613
3-Methylglutaconic Aciduria, Type Viib
Neonatal hypoglycemia OMIM:616271
3-Methylglutaconic Aciduria, Type Viii
Neonatal hypoglycemia, Neonatal death, Death in infancy OMIM:617248
Mitochondrial Dna Depletion Syndrome 6 (Hepatocerebral Type)
Hypoglycemia, Recurrent hypoglycemia OMIM:256810
Bannayan-Riley-Ruvalcaba Syndrome
Hypoglycemia ORPHA:109
Dilated Cardiomyopathy With Ataxia
Neonatal hypoglycemia ORPHA:66634
3-Hydroxy-3-Methylglutaric Aciduria
Nonketotic hypoglycemia, Recurrent hypoglycemia ORPHA:20
Orthostatic Hypotension 1
Neonatal hypoglycemia OMIM:223360
Pyruvate Carboxylase Deficiency
Hypoglycemia, Hyperglycemia ORPHA:3008
Neurodevelopmental Disorder With Hypotonia, Craniofacial Abnormalities, And Seizures
Hypoglycemia OMIM:614501
Mitochondrial Complex I Deficiency, Nuclear Type 1
Hypoglycemia, Death in infancy OMIM:252010
Wars2-Related Combined Oxidative Phosphorylation Defect
Neonatal hypoglycemia ORPHA:572798
Neurologic, Endocrine, And Pancreatic Disease, Multisystem, Infantile-Onset 2
Neonatal hypoglycemia, Hypoglycemia OMIM:619418
Congenital Syphilis
Hypoglycemia ORPHA:499009
Very Long Chain Acyl-Coa Dehydrogenase Deficiency
Hypoketotic hypoglycemia ORPHA:26793
Mitochondrial Trifunctional Protein Deficiency
Hypoketotic hypoglycemia ORPHA:746
Congenital Lipoid Adrenal Hyperplasia Due To Star Deficency
Hypoglycemia ORPHA:90790
Holoprosencephaly
Hypoglycemia, Diabetes mellitus ORPHA:2162
Shigellosis
Hypoglycemia ORPHA:810
Kabuki Syndrome 2
Neonatal hypoglycemia OMIM:300867
Sheehan Syndrome
Hypoglycemia ORPHA:91355
Deeah Syndrome
Neonatal hypoglycemia, Death in childhood, Death in adolescence, Death in infancy OMIM:619004
Fatal Infantile Lactic Acidosis With Methylmalonic Aciduria
Hypoglycemia ORPHA:17
Glutaryl-Coa Dehydrogenase Deficiency
Fasting hypoglycemia ORPHA:25
Alg12-Cdg
Recurrent hypoglycemia ORPHA:79324
Intellectual Developmental Disorder, X-Linked, Syndromic, With Pigmentary Mosaicism And Coarse Facies
Hypoglycemia OMIM:301066
Glycogen Storage Disease Ib
Hypoglycemia OMIM:232220
Multiple Endocrine Neoplasia, Type I
Hypoglycemia OMIM:131100
Methylmalonic Acidemia With Homocystinuria, Type Cblc
Hypoglycemia ORPHA:79282
Congenital Adrenal Hyperplasia Due To 3-Beta-Hydroxysteroid Dehydrogenase Deficiency
Neonatal hypoglycemia ORPHA:90791
Silver-Russell Syndrome Due To Maternal Uniparental Disomy Of Chromosome 7
Insulin resistance, Fasting hypoglycemia ORPHA:96182
Acute Adrenal Insufficiency
Hypoglycemia ORPHA:95409
Carnitine Palmitoyltransferase Ii Deficiency
Hypoketotic hypoglycemia ORPHA:157
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency Type Ib
Hypoglycemic seizures, Hypoglycemia ORPHA:79259
Renal Agenesis, Bilateral
Nonketotic hypoglycemia ORPHA:1848
Perlman Syndrome
Hypoglycemia OMIM:267000
Simpson-Golabi-Behmel Syndrome
Hypoglycemia, Death in infancy ORPHA:373
Histiocytoid Cardiomyopathy
Hypoglycemia ORPHA:137675
Carnitine Palmitoyl Transferase Ii Deficiency, Neonatal Form
Hypoketotic hypoglycemia ORPHA:228308
Menkes Disease
Hypoglycemia ORPHA:565
Leprechaunism
Hyperinsulinemia, Fasting hypoglycemia, Insulin resistance, Postprandial hyperglycemia, Recurrent... ORPHA:508
Addison Disease
Type I diabetes mellitus, Hypoglycemia ORPHA:85138
Hereditary Fructose Intolerance
Reactive hypoglycemia ORPHA:469
Generalized Glucocorticoid Resistance Syndrome
Hypoglycemia ORPHA:786
Glycogen Storage Disease Ic
Hypoglycemia OMIM:232240
Deficiency In Anterior Pituitary Function-Variable Immunodeficiency Syndrome
Recurrent hypoglycemia ORPHA:293978
Tyrosinemia, Type I
Hypoglycemia OMIM:276700
Rajab Interstitial Lung Disease With Brain Calcifications 1
Hypoglycemia OMIM:613658
Glycerol Kinase Deficiency
Hypoglycemia OMIM:307030
Hypothyroidism Due To Deficient Transcription Factors Involved In Pituitary Development Or Function
Hypoglycemia ORPHA:226307
Mitochondrial Complex Iv Deficiency, Nuclear Type 5
Hypoglycemia, Hyperglycemia, Death in infancy OMIM:220111
Fructose Intolerance, Hereditary
Glycosuria, Hypoglycemia OMIM:229600
Primary Fanconi Renotubular Syndrome
Glycosuria, Hypoglycemia ORPHA:3337
Glycogen Storage Disease Of Heart, Lethal Congenital
Neonatal hypoglycemia OMIM:261740
46,Xy Difference Of Sex Development-Adrenal Insufficiency Due To Cyp11A1 Deficiency
Neonatal hypoglycemia ORPHA:168558
Inherited Isolated Adrenal Insufficiency Due To Partial Cyp11A1 Deficiency
Neonatal hypoglycemia ORPHA:289548
Beckwith-Wiedemann Syndrome
Neonatal hypoglycemia, Hypoglycemia ORPHA:116
Costello Syndrome
Hypoglycemia OMIM:218040
Marburg Hemorrhagic Fever
Hypoglycemia ORPHA:99826
Neurooculorenal Syndrome
Recurrent hypoglycemia OMIM:620305
Megalencephaly-Severe Kyphoscoliosis-Overgrowth Syndrome
Neonatal hypoglycemia ORPHA:457359
Acute Liver Failure
Hypoglycemia ORPHA:90062
Non-Acquired Panhypopituitarism
Hypoglycemia ORPHA:90695
Classic Congenital Adrenal Hyperplasia Due To 21-Hydroxylase Deficiency
Neonatal hypoglycemia, Miscarriage ORPHA:90794
Holoprosencephaly 1
Hypoglycemia OMIM:236100
Combined Pituitary Hormone Deficiencies, Genetic Forms
Hypoglycemia ORPHA:95494
Antley-Bixler Syndrome With Genital Anomalies And Disordered Steroidogenesis
Hypoglycemia OMIM:201750
Beckwith-Wiedemann Syndrome
Neonatal hypoglycemia OMIM:130650
Sotos Syndrome
Neonatal hypoglycemia ORPHA:821

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Gga2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Gga2.

No publications found that use IMPC mice or data for Gga2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Gga2tm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Gga2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Gga2em1(IMPC)Ccpcz Exon Deletion Mice

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