Herc3 | hect domain and RLD 3

GeneMGI:1921248Synonyms: 5730409F18Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Growth/size/body region Behavior/neurological

17 No significant impact

5 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased lean body mass1 supporting datasetHerc3tm1a(EUCOMM)WtsihomozygoteEarly adult7.07x10-5 
abnormal response to new environment1 supporting datasetHerc3tm1a(EUCOMM)WtsihomozygoteEarly adult5.14x10-7 
trunk curl1 supporting datasetHerc3tm1a(EUCOMM)WtsihomozygoteEarly adult2.29x10-11 
tremors1 supporting datasetHerc3tm1a(EUCOMM)WtsihomozygoteEarly adult4.94x10-8 
abnormal tail movements1 supporting datasetHerc3tm1a(EUCOMM)WtsihomozygoteEarly adult8.81x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Herc3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse

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