Gene: Fam161a

Order

Name family with sequence similarity 161, member A

Synonyms 4930430E16Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1921123    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Fam161a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Fam161a data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
shortened RR interval Fam161atm1b(KOMP)Wtsi HOM Female Male postnatal 3.39E-8
increased heart rate Fam161atm1b(KOMP)Wtsi HOM Female Male postnatal 1.81E-7
decreased exploration in new environment Fam161atm1b(KOMP)Wtsi HOM Female Male postnatal 2.71E-7
decreased coping response Fam161atm1b(KOMP)Wtsi HOM Female Male postnatal 7.92E-7
increased grip strength Fam161atm1b(KOMP)Wtsi HOM Female Male postnatal 2.16E-6
cardiovascular system phenotype Fam161atm1b(KOMP)Wtsi HOM Female Male postnatal 2.38E-5
decreased heart rate variability Fam161atm1b(KOMP)Wtsi HOM Female Male postnatal 8.02E-5
convulsive seizures Fam161atm1b(KOMP)Wtsi HOM Female Male postnatal 9.05E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562) (2/2)
Bone 2 No (1/539)
Bone marrow 2 No
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Epididymis 2 No (4/106)
Esophagus 2 No (2/393)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Main olfactory bulb 2 No
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No (4/393)
Ovary 2 No (1/562)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393) (1/2)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Quadriceps 2 No
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562) (1/2)
Submandibular gland 2 No (1/104)
Testis 2 No (4/562) (1/2)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562) (1/2)
Urinary bladder 2 No
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    digestive system
    cardiovascular system
    nervous system
    sensory organ
    reproductive system
    immune system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/440)
Dorsal root ganglion 1 (1/3)
Ear 2 (1/440)
Embryo 2 (1/440)
Eye 2 (1/440)
Foot 2
Forebrain 2 (1/440)
Forelimb 2 (1/440)
Fronto-nasal process 1 (1/4)
Hand 2
Head 2 (5/440)
Heart 2 (1/440)
Hindbrain 2 (5/440)
Hindlimb 2 (1/440)
Liver 2 (1/440)
Lung 2 (1/440)
Mandibular process 2 (1/440)
Maxillary process 2 (1/440)
Midbrain 2 (1/440)
Nose 1 (1/5)
Oral cavity 2 (1/440)
Skin 2 (1/440)
Spinal cord 1 (1/4)
Tail 2 (1/440)
Tail somite 2 (1/440)


Associated Images

Associated Images
  • X-ray: XRay Images Forepaw
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    11 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    11 Images
  • Electroretinography: Rod waveform (pdf format)
    2 Images
  • Electroretinography: Cone waveform (pdf format)
    2 Images
  • X-ray: XRay Images Dorso Ventral
    11 Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • Sleep Wake: Wake state (bmp file)
    15 Images
  • Electroretinography 2: Rod and cone PDF
    2 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Fam161atm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Fam161atm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene