Gene: Col20a1

Name
collagen, type XX, alpha 1
MGI ID
MGI:1920618
Synonyms
1700051I12Rik
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (56) Expression & images (0) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

Mouseover the data points for more information. Click and drag to zoom the chart. Click on the legends to disable/enable data.

Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Alanine aminotransferase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.148 Success
Col20a1em1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / RR HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.235 Success
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Creatinine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.815 Success
Col20a1em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.311 Success
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Alkaline phosphatase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.314 Success
Col20a1em1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / PR HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0790 Success
Col20a1em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 0.573 Success
Col20a1em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Total cholesterol HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.521 Success
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Total protein HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.735 Success
Col20a1em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.318 Success
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Albumin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.665 Success
Col20a1em1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / HR HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.252 Success
Col20a1em1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.421 Success
Col20a1em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Bone Area HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.626 Success
Col20a1em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Col20a1em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Body length HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.196 Success
Col20a1em1(IMPC)Mbp UC Davis Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.395 Success
Col20a1em1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.835 Success
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Total bilirubin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.218 Success
Col20a1em1(IMPC)Mbp UC Davis Eye Morphology / Lens Opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Aspartate aminotransferase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.965 Success
Col20a1em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.229 Success
Col20a1em1(IMPC)Mbp UC Davis Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.628 Success
Col20a1em1(IMPC)Mbp UC Davis Eye Morphology / Cornea HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Col20a1em1(IMPC)Mbp UC Davis Eye Morphology / Retina (combined) HOM 8f:7m Not processed Success
Col20a1em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Col20a1em1(IMPC)Mbp UC Davis Eye Morphology / Lens HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Calcium HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.329 Success
Col20a1em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0787 Success
Col20a1em1(IMPC)Mbp UC Davis Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.478 Success
Col20a1em1(IMPC)Mbp UC Davis Eye Morphology / Optic Disc HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Glucose HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.112 Success
Col20a1em1(IMPC)Mbp UC Davis Eye Morphology / Retinal Blood Vessels Structure HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Col20a1em1(IMPC)Mbp UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Col20a1em1(IMPC)Mbp UC Davis Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.684 Success
Col20a1em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.210 Success
Col20a1em1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.677 Success
Col20a1em1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.430 Success
Col20a1em1(IMPC)Mbp UC Davis Eye Morphology / Retinal Blood Vessels HOM 8f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Col20a1em1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / QRS HOM 8f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.149 Success
Col20a1em1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.365 Success
Col20a1em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Fat mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.416 Success
Col20a1em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Phosphorus HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.405 Success
Col20a1em1(IMPC)Mbp UC Davis Insulin Blood Level / Insulin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.837 Success
Col20a1em1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.859 Success
Col20a1em1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.486 Success
Col20a1em1(IMPC)Mbp UC Davis Viability Primary Screen / Outcome HOM 60f:61m Supplied as data Success
Col20a1em1(IMPC)Mbp UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Col20a1em1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Lean mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0544 Success
Col20a1em1(IMPC)Mbp UC Davis Eye Morphology / Corneal opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Col20a1em1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / ST HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000986 Success
Col20a1em1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Triglycerides HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0184 Success
Col20a1em1(IMPC)Mbp UC Davis Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00218 Success

 Expression

Expression data not available

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Col20a1em1(IMPC)Mbp Exon Deletion Mice, Tissue
Col20a1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Col20a1tm115804(L1L2_Bact_P) Targeting vectors

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter