Gene: Arhgef6

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Name
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
MGI ID
MGI:1920591
Synonyms
1700038J06Rik 1600028C08Rik 4930592P22Rik alpha-PIX
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
enlarged lymph nodes Arhgef6tm2e.1(EUCOMM)Wtsi HEM Early adult 0.00
increased heart weight Arhgef6tm2e.1(EUCOMM)Wtsi HOM   Early adult 5.92×10-05
decreased basophil cell number Arhgef6tm2e.1(EUCOMM)Wtsi HEM   Early adult 1.46×10-18

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: Images Slit Lamp
1 Images
Immunophenotyping: Panel A FCS file(s)
6 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Combined SHIRPA and Dysmorphology
1 Images
Immunophenotyping: Panel B FCS file(s)
6 Images
Histopathology
4 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Spleen - hyperplasia Arhgef6tm2e.1(EUCOMM)Wtsi HEM Early adult
Spleen - hyperplasia Arhgef6tm2e.1(EUCOMM)Wtsi HOM Early adult

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MGI Allele Allele Type Produced
Arhgef6tm2e.1(EUCOMM)Wtsi Mice, Tissue
Arhgef6tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Arhgef6tm40717(L1L2_gt0) Targeting vectors
Arhgef6tm2e(EUCOMM)Wtsi Targeted, non-conditional allele Mice

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