Gene: Nfatc4

Name
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
MGI ID
MGI:1920431
Synonyms
3110041H08Rik
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Alanine aminotransferase HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.496 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.128 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris/Pupil HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Hematology / Mean cell hemoglobin concentration HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.768 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal deposits HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Open Field / Percentage center time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.938 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Body length HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0730 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Open Field / Periphery distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.273 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Light-Dark Test / Dark side time spent HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0433 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep light phase percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0470 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Tail Suspension / Latency to immobility HOM 8f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.502 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Calcium HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0645 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Hematology / Hematocrit HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0640 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.208 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0951 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Rotarod / Learning slope HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.413 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Dilation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Fat mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00110 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Potassium HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0283 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.541 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 0f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 0.216 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Phosphorus HOM 5f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Viability Primary Screen / Outcome HOM 44f:51m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00186 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0147 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electroretinography 2 / Rod b-wave amplitude HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Open Field / Center distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.566 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 0.273 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in dark HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0117 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Triglycerides HOM 5f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_017_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Nfatc4tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 8f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.818 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electroconvulsive Threshold Testing / mA threshold inducing clonic seizure HOM 0f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Light sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0119 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / PQ HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.476 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Hematology / Platelet count HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.467 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total protein HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.928 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Position HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0257 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile light side HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0465 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.531 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris transilumination HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Aspartate aminotransferase HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.967 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Tail Suspension / Time immobile HOM 8f:5m Mixed Model framework, generalized least squares, equation withoutWeight 0.0212 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.688 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Hematology / Hemoglobin HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0936 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electroretinography 2 / Rod b-wave amplitude-left HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Open Field / Whole arena resting time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.451 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Vitreous HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 0.208 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QTc HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.102 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.124 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Open Field / Center average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.236 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Sodium HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0207 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep dark phase percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0468 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Heart Weight / Heart weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0862 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0402 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / HDL-cholesterol HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.554 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 0.0666 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.671 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 0f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00246 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 0f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Light-Dark Test / Latency to first transition into dark HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.876 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Open Field / Periphery average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.109 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QTc Dispersion HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.665 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.331 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Light-Dark Test / Percent time in light HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0117 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.103 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / rMSSD HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.501 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Open Field / Distance travelled - total HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.295 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.170 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Dark sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.226 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Synechia HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Iron HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.790 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 0.133 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total cholesterol HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.255 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Light-Dark Test / Light side time spent HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0433 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Open Field / Periphery permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.939 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Albumin HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.988 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.119 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.781 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electroretinography 2 / Rod b-wave amplitude-right HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Grip Strength / Forelimb grip strength measurement mean HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.268 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Hematology / Mean cell volume HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0865 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep daily percent HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.927 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Free fatty acids HOM 4f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_026_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Nfatc4tm1.1(KOMP)Vlcg JAX Open Field / Center permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.938 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00121 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Hematology / Red blood cell count HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00818 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0938 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Light-Dark Test / Fecal boli HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.764 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Iris Pigmentation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / HRV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.162 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Breath rate during sleep mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.468 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.724 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 0f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000379 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Electroretinography 2 / Rod a-wave amplitude-right HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 0.659 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Rotarod / Average duration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.314 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 5f:3m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_CBC_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Light-Dark Test / Side changes HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.207 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal Sclerization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Alkaline phosphatase HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0440 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Hole-board Exploration / Total holepokes HOM 5f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.993 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electroretinography 2 / Cone b-wave amplitude HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Open Field / Number of rears - total HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.249 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 3f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_037_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 0f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Bone Area HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.322 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Fusion between cornea and lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Hematology / Mean corpuscular hemoglobin HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0408 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electroretinography 2 / Rod b-wave implicit time HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00232 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Total bilirubin HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.848 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / CV HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.160 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Electroretinography 2 / Cone b-wave amplitude-left HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.203 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Electroretinography 2 / Cone b-wave amplitude-right HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Peak wake with respect to dark onset median HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.129 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Light-Dark Test / Time mobile dark side HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.748 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Glucose HOM 3f:3m Not processed 1.00 FAILED - Not enough mutant measurements (3f/3m)
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Tail Suspension / Climbing HOM 8f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electroretinography 2 / Rod a-wave implicit time HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.985 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Electroretinography 2 / Rod a-wave amplitude HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Clinical Chemistry / Chloride HOM 5f:4m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00142 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Insulin Blood Level / Insulin HOM 8f:5m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.636 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Rotarod / Learning difference HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.317 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 3f:4m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_ACS_036_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Nfatc4tm1.1(KOMP)Vlcg JAX Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 0f:3m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Body Composition (DEXA lean/fat) / Lean mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.103 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Open Field / Whole arena average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.296 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Sleep Wake / Sleep bout lengths standard deviation HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00123 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Nfatc4tm1.1(KOMP)Vlcg JAX Electroretinography 2 / Rod a-wave amplitude-left HOM 2f:1m Not processed 1.00 FAILED - Not enough mutant or control data
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Nfatc4tm1.1(KOMP)Vlcg JAX Hematology / White blood cell count HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.281 Success
Nfatc4tm1.1(KOMP)Vlcg JAX Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No  (1/2) N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (1/3) N/A
Dorsal root ganglion 2  (1/47) Image Only N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485) N/A
Foot 2  (1/485)  (1/3) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485)  (2/3) N/A
Fronto-nasal process 2  (1/48) Image Only N/A
Hand 2  (1/485)  (1/3) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485)  (1/3) N/A
Hindlimb 2  (1/485)  (2/3) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485)  (2/3) N/A
Maxillary process 2  (1/485)  (2/3) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) Image Only N/A
Skin 2  (1/485) Image Only N/A
Spinal cord 2  (1/50)  (1/3) N/A
Tail 2  (1/485)  (2/3) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Forepaw
10 Images
Sleep Wake: Wake state (bmp file)
14 Images
Electroretinography 2: Rod and cone PDF
3 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Nfatc4tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Nfatc4tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice

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