Gene: Tppp

Name
tubulin polymerization promoting protein
MGI ID
MGI:1920198
Synonyms
2900041A09Rik
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased hematocrit Tppptm1.1(KOMP)Vlcg HOM postnatal 2.90×10-07
hyperactivity Tppptm1.1(KOMP)Vlcg HOM postnatal 1.01×10-07
decreased lean body mass Tppptm1.1(KOMP)Vlcg HOM postnatal 5.03×10-06
decreased bone mineral content Tppptm1.1(KOMP)Vlcg HOM postnatal 2.10×10-05
decreased body length Tppptm1.1(KOMP)Vlcg HOM postnatal 2.28×10-07
abnormal sleep behavior Tppptm1.1(KOMP)Vlcg HOM postnatal 3.02×10-09
decreased bone mineral density Tppptm1.1(KOMP)Vlcg HOM postnatal 4.78×10-05
increased circulating chloride level Tppptm1.1(KOMP)Vlcg HOM postnatal 1.86×10-09
decreased anxiety-related response Tppptm1.1(KOMP)Vlcg HOM postnatal 1.27×10-06
increased hemoglobin content Tppptm1.1(KOMP)Vlcg HOM postnatal 4.22×10-12
increased erythrocyte cell number Tppptm1.1(KOMP)Vlcg HOM postnatal 1.94×10-10
abnormal behavioral response to light Tppptm1.1(KOMP)Vlcg HOM postnatal 1.77×10-10
abnormal bone structure Tppptm1.1(KOMP)Vlcg HOM postnatal 3.40×10-06
increased circulating alkaline phosphatase level Tppptm1.1(KOMP)Vlcg HOM postnatal 9.31×10-06
convulsive seizures Tppptm1.1(KOMP)Vlcg HOM postnatal 5.39×10-18

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (1/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (1/2) N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/3) N/A
Dorsal root ganglion 2  (1/47) Image Only N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/3) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485)  (2/3) N/A
Forelimb 2  (1/485)  (2/3) N/A
Fronto-nasal process 2  (1/48) Image Only N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485) Image Only N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485)  (2/3) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485)  (2/3) N/A
Nose 2  (1/51)  (2/3) N/A
Oral cavity 2  (1/485) Image Only N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50)  (2/3) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

Sleep Wake: Wake state (bmp file)
16 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Tppptm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Tppptm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Tppptm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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