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Genes Phenotypes

Gene: Ddx41

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Name
DEAD box helicase 41
MGI ID
MGI:1920185
Synonyms
2900024F02Rik DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
Viability
Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (217) All data table (532)
Expression & images (70) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Ddx41tm1b(KOMP)Wtsi HOM E12.5 0.00
abnormal embryo size Ddx41tm1b(KOMP)Wtsi HET E9.5 0.00
embryonic lethality prior to organogenesis Ddx41tm1b(KOMP)Wtsi HOM E9.5 0.00
increased bone mineral content Ddx41tm1b(KOMP)Wtsi HET Early adult 1.37×10-05
decreased fasting circulating glucose level Ddx41tm1b(KOMP)Wtsi HET Early adult 4.35×10-05
preweaning lethality, complete penetrance Ddx41tm1b(KOMP)Wtsi HOM Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (1/2) N/A
Aorta 2 No  (1/590) N/A
Brain 2 No  (3/590)  (2/2) N/A
Brainstem 2 No  (2/590) N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590)  (1/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590)  (2/2)  Section images
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590)  (2/2) N/A
Large intestine 2 No  (10/590)  (1/2) N/A
Liver 2 No  (1/2) N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/590) N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590)  (1/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590)  (1/2) N/A
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590) N/A
Testis 2 No  (5/590)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/590)  (1/2) N/A
Trachea 2 No  (2/590) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
nervous system (5)
Hippocampus expression
MA:0000191
postnatal mouse (5)
Hippocampus expression
MA:0000191
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/65) N/A
Brain 5  (6/506) N/A
Central nervous system ganglion 2  (1/74) N/A
Ear 5  (1/506) N/A
Embryo 5  (1/507)  (2/5) N/A
Eye 5  (1/506)  (2/5) N/A
Foot 5  (1/506) N/A
Forebrain 5  (1/506) N/A
Forelimb 5  (1/506) N/A
Gut 2  (1/60) N/A
Hand 5  (1/506) N/A
Head 5  (5/506) N/A
Heart 5  (1/506)  (2/5) N/A
Hindbrain 5  (6/506) N/A
Hindlimb 5  (1/506) N/A
Liver 5  (1/504) N/A
Lung 5  (1/504)  (2/5) N/A
Mandibular process 5  (1/506) N/A
Maxillary process 5  (1/506) N/A
Midbrain 5  (1/506) N/A
Nose 2  (1/76) N/A
Oral cavity 5  (1/504) Image Only N/A
Skeleton 2  (1/76) N/A
Skin 5  (1/506) N/A
Spinal cord 2  (1/73) N/A
Tail 5  (1/506) N/A
Tail somite 5  (1/506) N/A
Trachea 2  (1/60) N/A
Urinary system 2  (1/60)  (2/2) N/A

 Associated Images

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X-ray: XRay Images Whole Body Dorso Ventral
14 Images
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Gross Pathology and Tissue Collection
8 Images
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X-ray: XRay Images Whole Body Lateral Orientation
14 Images
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X-ray: XRay Images Skull Lateral Orientation
14 Images
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Embryo LacZ: LacZ images wholemount
20 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
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Adult LacZ: LacZ Images Section
5 Images
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Eye Morphology: Images Ophthalmoscopy
2 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ddx41tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Ddx41tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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