Genes Phenotypes

Gene: Setd5

Name
SET domain containing 5
MGI ID
MGI:1920145
Synonyms
2900045N06Rik
Viability
Homozygous - Lethal
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (12) Measurements chart (434) All data table (541)
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Setd5tm1a(EUCOMM)Wtsi HOM n/a 0.00
decreased circulating glucose level Setd5tm1a(EUCOMM)Wtsi HET postnatal 5.16×10-05
increased Ly6C low monocyte number Setd5tm1a(EUCOMM)Wtsi HET postnatal 0.00
abnormal cranium morphology Setd5tm1a(EUCOMM)Wtsi HET postnatal 8.39×10-10
abnormal maxilla morphology Setd5tm1a(EUCOMM)Wtsi HET postnatal 5.57×10-07
absent pinna reflex Setd5tm1a(EUCOMM)Wtsi HET postnatal 1.61×10-05
abnormal tooth morphology Setd5tm1a(EUCOMM)Wtsi HET postnatal 4.24×10-06
decreased grip strength Setd5tm1a(EUCOMM)Wtsi HET postnatal 1.02×10-05
vertebral fusion Setd5tm1a(EUCOMM)Wtsi HET postnatal 4.94×10-05
abnormal coat/hair pigmentation Setd5tm1a(EUCOMM)Wtsi HET postnatal 1.74×10-09
abnormal snout morphology Setd5tm1a(EUCOMM)Wtsi HET postnatal 1.91×10-05
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Setd5tm1a(EUCOMM)Wtsi HET postnatal 0.00

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Dorso Ventral
42 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Lateral Orientation
28 Images
DSS Histology
6 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Anti-nuclear antibody assay
6 Images
Eye Morphology: Images Slit Lamp
1 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Setd5tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Setd5tm39685(L1L2_st2) Targeting vectors
Setd5tm39685(L1L2_gt1) Targeting vectors

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