Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
zinc finger with KRAB and SCAN domains 3
Synonyms:
Zfp306,  Zfp307,  Skz1,  2810435N07Rik

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Zkscan3 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Zkscan3 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Leishmaniasis, Tegumentary, Susceptibility To
Tegumentary leishmaniasis susceptibility OMIM:602068
Ciliary Discoordination Due To Random Ciliary Orientation
Recurrent infections OMIM:215518
Coxsackievirus B3 Susceptibility
Recurrent viral infections OMIM:120050
Human Coronavirus Sensitivity
Susceptibility to coronavirus 229e OMIM:122460
Varicella, Severe Recurrent
Severe recurrent varicella OMIM:600670
Immunodeficiency 30
Recurrent infections, Recurrent mycobacterial infections OMIM:614891
Neutrophil Actin Dysfunction
Recurrent bacterial infections OMIM:257150

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Zkscan3

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Zkscan3.

No publications found that use IMPC mice or data for Zkscan3.

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MGI Allele Allele Type Produced
Zkscan3tm208549(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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