Adipor1 | adiponectin receptor 1

GeneMGI:1919924Synonyms: 2810031L11Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:19Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lymphocyte cell number	1 supporting dataset	Adipor1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.35x10^-5
decreased circulating calcium level	2 supporting datasets	Adipor1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.47x10^-7
increased circulating HDL cholesterol level	1 supporting dataset	Adipor1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.56x10^-13
abnormal retina morphology	2 supporting datasets	Adipor1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.15x10^-16
decreased cornea thickness	1 supporting dataset	Adipor1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.28x10^-7
decreased total retina thickness	2 supporting datasets	Adipor1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.14x10^-29
increased circulating triglyceride level	1 supporting dataset	Adipor1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.63x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Adipor1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.29x10^-5
abnormal heart left ventricle morphology	1 supporting dataset	Adipor1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.81x10^-5
abnormal auditory brainstem response	1 supporting dataset	Adipor1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.65x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adipor1.

Associated images

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Histopathology

There is no histopathology data found for Adipor1.

IMPC related publications

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External links

No external links available for Adipor1.

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*Adipor1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Adipor1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Adipor1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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