Gene: Iars2

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Name
isoleucine-tRNA synthetase 2, mitochondrial
MGI ID
MGI:1919586
Synonyms
2010002H18Rik
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Iars2em1(IMPC)Tcp HOM   E9.5 0.00
abnormal eye morphology Iars2em1(IMPC)Tcp HET Early adult 0.00
preweaning lethality, complete penetrance Iars2em1(IMPC)Tcp HOM   Early adult 0.00
prenatal lethality prior to heart atrial septation Iars2em1(IMPC)Tcp HOM   E15.5 0.00
increased hematocrit Iars2em1(IMPC)Tcp HET Early adult 1.13×10-06
increased hemoglobin content Iars2em1(IMPC)Tcp HET Early adult 8.45×10-05

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Gross Morphology Embryo E14.5-E15.5
11 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Eye Morphology: Images Ophthalmoscopy
8 Images
Immunophenotyping: Panel A FCS file(s)
6 Images
Immunophenotyping: Panel B FCS file(s)
6 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Iars2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Iars2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Iars2em1(IMPC)Tcp Exon Deletion Mice

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