Tmem68 | transmembrane protein 68

GeneMGI:1919348Synonyms: Diesl, 2010300G19Rik

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal response to tactile stimuli1 supporting datasetTmem68tm1a(EUCOMM)WtsihomozygoteEarly adult3.68x10-12 
abnormal glucose homeostasis1 supporting datasetTmem68tm1a(EUCOMM)WtsihomozygoteEarly adult4.39x10-6 
increased circulating aspartate transaminase level1 supporting datasetTmem68tm1a(EUCOMM)WtsihomozygoteEarly adult8.06x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tmem68tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Tmem68tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Tmem68tm47153(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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