Prmt3 - protein arginine N-methyltransferase 3 | International Mouse Phenotyping Consortium

Genes Phenotypes

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Gene: Prmt3

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Name

protein arginine N-methyltransferase 3

MGI ID

MGI:1919224

Synonyms

2010005E20Rik Hrmt1l3 2410018A17Rik

Viability

N/A

Embryo viewer

N/A

Other links

MGI Ensembl

Significant phenotypes (4) Measurements chart (146) All data table (431)

Expression & images (45) Disease models (0) Order (1)

Significant

Not Significant

Not tested

Phenotype	System	Allele	Zyg	Sex	Life Stage	P Value
abnormal snout morphology		Prmt3^{tm1a(EUCOMM)Wtsi}	HOM		Early adult	7.98×10^-05
abnormal head morphology		Prmt3^{tm1a(EUCOMM)Wtsi}	HOM		Early adult	1.24×10^-05
decreased body weight		Prmt3^{tm1a(EUCOMM)Wtsi}	HOM		Early adult	9.72×10^-07
abnormal eye size		Prmt3^{tm1a(EUCOMM)Wtsi}	HOM		Early adult	3.60×10^-07

Download data as: TSV XLS

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Viewing: all phenotypes

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Viewing: all phenotypes

Expression

IMPC lacZ Expression Data

Adult Expression (45)
Embryo Expression (0)

Table Images

Expression No Expression Ambiguous No Tissue Available

Anatomy	#HET Specimens	HOM Images?	WT Expr	Mutant Expr	Images
Adrenal gland	2	No	(2/584)		N/A
Aorta	2	No			N/A
Blood vessel	2	No			N/A
Bone	2	No			N/A
Brain	2	No		(2/2)	N/A
Brainstem	2	No			N/A
Brown adipose tissue	2	No			N/A
Cartilage tissue	2	No		(2/2)	N/A
Cerebellum	2	No			N/A
Cerebral cortex	2	No			N/A
Eye	2	No			N/A
Gall bladder	2	No			N/A
Heart	2	No			N/A
Hippocampus	2	No			N/A
Hypothalamus	2	No			N/A
Kidney	2	No	(18/584)		N/A
Large intestine	2	No	(10/584)		N/A
Liver	2	No			N/A
Lower urinary tract	2	No			N/A
Lung	2	No			N/A
Lymph node	2	No			N/A
Mammary gland	2	No			N/A
Esophagus	2	No			N/A
Olfactory lobe	2	No			N/A
Ovary	2	No	(1/584)		N/A
Oviduct	2	No			N/A
Pancreas	2	No	(5/584)		N/A
Parathyroid gland	2	No			N/A
Peripheral nervous system	2	No		(2/2)	N/A
Peyer's patch	2	No			N/A
Pituitary gland	2	No			N/A
Prostate gland	2	No	(12/584)		N/A
Skeletal muscle tissue	2	No			N/A
Skin	2	No			N/A
Small intestine	2	No	(9/584)		N/A
Spinal cord	2	No		(2/2)	N/A
Spleen	2	No	(2/584)		N/A
Stomach	2	No	(12/584)		N/A
Striatum	2	No			N/A
Testis	2	No	(2/584)	(1/2)	N/A
Thymus	2	No			N/A
Thyroid gland	2	No	(15/584)		N/A
Trachea	2	No		(2/2)	N/A
Uterus	2	No			N/A
White adipose tissue	2	No			N/A

LacZ Wholemount Images

LacZ Section Images

LacZ Section Images

Prmt3^{tm1a(EUCOMM)Wtsi}
cartilage tissue, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
trachea, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
testis, HET, Male, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
brain, HET, Male, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
brain, HET, Male, WTSI

View all 8 images

Prmt3^{tm1a(EUCOMM)Wtsi}
brain, HET, Male, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
brain, HET, Male, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
peripheral nervous system, HET, Male, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
spinal cord, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
trachea, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
testis, HET, Male, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
spinal cord, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
ovary, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
testis, HET, Male, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
ovary, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
trachea, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
cartilage tissue, HET, Female, WTSI

No Embryo expression data was found for this gene.

Associated Images

Legacy Phenotype Associated Images

Prmt3^{tm1a(EUCOMM)Wtsi}
head, WT, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
body, WT, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
head, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
body, HET, Male, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
forearm, HET, Male, WTSI

View all 163 images

Prmt3^{tm1a(EUCOMM)Wtsi}
back skin, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
back skin, HOM, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
back skin, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
back skin, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
back skin, HOM, Female, WTSI

View all 6 images

Prmt3^{tm1a(EUCOMM)Wtsi}
eye, narrow eye opening, HOM, Male, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
eye, narrow eye opening, corneal opacity, HOM, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
eye, corneal opacity, HET, Female, WTSI

Prmt3^{tm1a(EUCOMM)Wtsi}
abnormal snout morphology, abnormal head shape, HOM, Male, WTSI

Disease Models

By Annotation and Orthology (0)
By phenotypic Similarity (0)

No associations by disease annotation and gene orthology found.

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MGI Allele	Allele Type	Produced
Prmt3^{tm1a(EUCOMM)Wtsi}	KO first allele (reporter-tagged insertion with conditional potential)	Mice, Targeting vectors, ES Cells

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